合成目标产物 Bisoctrizole 主要起始原料 Formaldehyde And Uv-329
(文献来源)合成步骤主要原料 Formaldehyde 和 Uv-329
2,2'-Methylene-Bis[6-(2-Nitrophenyl)Azo-4-(1,1,3,3-Tetramethylbutyl)-Phenol]置于n-甲基吡咯烷酮,Sodium Azide体系中,化学反应 8.0H,以24%的收率获得紫外光吸收剂 Uv-360 参考文献:Process For The Preparation Of Benzotriazoles 标题:Process For The Preparation Of Benzotriazoles 摘要:一种制备化合物的方法,其化学式为(i):其中一般符号如权利要求书中所定义,包括将化合物的化学式为(v):其中r1,R2,R3,R4,R5,R6,R7,R8,R9和r18如权利要求书中所定义,且r18特别是硝基,氯或溴,与化学式为(ix)的叠氮化合物发生反应:其中m和n如权利要求书中所定义,特别是与叠氮化钠反应.
专利号:US-9757317-B2 优先权日:2014-09-12 标题 :Cosmetic compositions and methods for inhibiting melanin synthesis 发明人:LAUGHLIN II LEO TIMOTHY; HAKOZAKI TOMOHIRO; GUPTA SHIKHAR 权利人:PROCTER & GAMBLE 摘要:A cosmetic composition suitable for topical application, for example, is provided. In some examples, the cosmetic composition may include bisabolol, undecylenoyl phenylalanine and/or hexyldecanol, and a material selected from the group consisting of ethyl palmitate, stearyl alcohol, bis (2-ethylhexyl) adipate, bis (2-ethylhexyl) maleate, 5-pentadecanol, 1-stearoyl-rac-glycerol, bis (2-ethylhexyl) sebacate, and mixtures thereof. A method of reducing the synthesis of melanin by using the cosmetic compositions is also disclosed herein.
专利号:US-9498420-B2 优先权日:2013-05-01 标 题:Cosmetic compositions and methods for inhibiting melanin synthesis 发明人:LAUGHLIN II LEO TIMOTHY; HAKOZAKI TOMOHIRO; TANAKA SHUHEI 权利人:PROCTER & GAMBLE 摘要:A cosmetic composition suitable for topical application, for example, is provided. In some examples, the cosmetic composition may include batyl alcohol, undecylenoyl phenylalanine, hexyldecanol, and bisabolol. A method of reducing the synthesis of melanin by using the cosmetic compositions is also disclosed herein.
专利号:US-2009318592-A1 优先权日:2005-10-11 标 题 :Process for the Synthesis of Amine Ethers 发明人:FREY MARKUS; BROENNIMANN VALERIE 权利人:CIBA GEIGY CORP 摘要:The present invention relates to novel processes for the preparation of a sterically hindered amine ether by reacting a corresponding sterically hindered amine oxide with a ketone or an aldehyde with at least one reactive H in the presence of a peroxydisulphate. Products obtained by this process may be hydrogenated. The compounds made by these processes are particularly effective in the stabilization of polymer compositions against harmful effects of light, oxygen and/or heat and as flame-retardants for polymers.
专利号:US-2007191516-A1 优先权日:2004-03-15 标题 :Process for the synthesis of amine ethers 发明人:FREY MARKUS; RAST VALERIE; BRAIG ADALBERT; KRAMER ANDREAS 权利人:FREY MARKUS; RAST VALERIE; BRAIG ADALBERT; KRAMER ANDREAS 摘要:A process for the preparation of a sterically hindered amine ether which comprises reacting a corresponding sterically hindered aminoxide with a C 5 -C 18 alk-1-ene in the presence of an organic hydroperoxide and optionally hydrogenating the resulting product as well as the product mixtures obtained therewith and their use as stabilizers and flame retardants.
专利号:US-2023047214-A1 优先权日:2020-02-03 标题:Methods for microwave synthesis of degradable polymers for drug delivery 发明人:MURATOGLU ORHUN K; ORAL EBRU; GRINDY SCOTT 权利人:MASSACHUSETTS GEN HOSPITAL 摘要:Provided herein are methods of making degradable, additive-blended polymeric materials using microwave radiation and catalysts. The methods can include incorporation of therapeutic materials into the polymeric materials. There also are provided polymeric materials made by the methods and medical devices comprising the polymeric materials made by the methods.
专利号:US-8546600-B2 优先权日:2008-10-08 标题:Slurry process for synthesis of bisphosphites and situ use thereof for producing bisphosphite 发明人:MILLER GLENN A 权利人:MILLER GLENN A; DOW TECHNOLOGY INVESTMENTS LLC 摘要:The present invention provides a step-wise process for preparation of a bisphosphite. In step (a) the process prepares a phosphoromonochloridite in high yield, by contacting phosphorus trichloride with an aromatic diol in a slurry under reaction conditions and in the presence of a second aromatic diol to produce a mixture comprising the phosphoromonochloridite, the second aromatic diol, and excess PCl3. The slurry comprises less than 5 mole percent of a nitrogen base, and the organic solvent is selected for its low hydrogen chloride solubility. After removing the excess PCl3, a nitrogen base is added to effect condensation of the phosphoromonochloridite with the second aromatic diol to yield the bisphosphite. The invention particularly provides a process for preparing 6,6′-(3,3′,5,5′-tetra-tert-butylbiphenyl-2,2′-diyl)bis(oxy)didibenzo[d,f][1,3,2]dioxaphosphepine by the above route.
1: Apel C, Joerss H, Ebinghaus R. Environmental occurrence and hazard of organic UV stabilizers and UV filters in the sediment of European North and Baltic Seas. Chemosphere. 2018 Dec;212:254-261. doi: 10.1016/j.chemosphere.2018.08.105. Epub 2018 Aug 20. 144:76-84. doi: 10.1016/j.jphotobiol.2015.01.015. Epub 2015 Feb 17. 63(2):103-17. 22(2):106-11. 60(6):587-98.
合成参考文献
摘要:European Commission Scientific Committee on Consumer Safety