CAS: 13532-18-8; Methyl3-(Methylthio)Propionate

相似化合物

505-10-2 646-01-5 13327-56-5

上下游产品

methylthiol Methyl 3-bromopropionate acrylic acid methyl ester methyl 3-chloropropionate3-methanesulfonyl-propionic acid methyl ester (2-methoxycarbonyl-ethyl)-dimethyl sulfonium ; iodide 3-(methylthio)-1-propanol 3O2(1-)CCl3O2(1-)

3-(Methylsulfinyl)Propionic Acid Methyl Ester置于n,N,N',N'-Tetrabromobenzene-1,3-Disulfonamide,三苯基膦体系中,用 二氯甲烷 用作溶剂,化学反应 0.02H,以90%的收率获得3-甲硫基丙酸甲酯
参考文献:A Novel Method For The Reduction Of Sulfoxides With The N,N,N',N'-Tetrabromobenzene-1,3-Disulfonamide (Tbbda)/pph3 System
标题:A Novel Method For The Reduction Of Sulfoxides With The N,N,N',N'-Tetrabromobenzene-1,3-Disulfonamide (Tbbda)/pph3 System
摘要:摘要 描述了一种使用n,N,N',N'-四溴苯-1,3-二磺酰胺[tbbda]与三苯基膦结合的方法,将磺氧化物还原为硫化物.该方法具有非常好至优异的收率,短反应时间,高效性和便捷的产物分离等优点.
Doi:10.1016/j.Crci.2013.11.006

专利信息

专利号:US-9409945-B2
优先权日:1999-10-04
标 题 :Combinatorial synthesis of libraries of macrocyclic compounds useful in drug discovery
发明人：DESLONGCHAMPS PIERRE; DORY YVES; BERTHIAUME GILLES; OUELLET LUC; LAN RUOXI
权利人:OCERA THERAPEUTICS INC
摘要:A library of macrocyclic compounds of the formula (I) n n n n n n n n n n n n where part (A) is a n n n n n n n n n n n n n n n n  bivalent radical, a —(CH 2 ) y — bivalent radical or a covalent bond; n where part (B) is a n n n n n n n n n n n n n n n n  bivalent radical, a —(CH 2 ) z — bivalent radical, or a covalent bond; n where part (C) is a n n n n n n n n n n n n n n n n  bivalent radical, a —(CH 2 ) t — bivalent radical, or a covalent bond; and n where part (T) is a —Y-L-Z— radical wherein Y is CH 2 or CO, Z is NH or O and L is a bivalent radical. These compounds are useful for carrying out screening assays or as intermediates for the synthesis of other compounds of pharmaceutical interest. A process for the preparation of these compounds in a combinatorial manner, is also disclosed.

专利号:US-9617372-B2
优先权日:2012-10-24
标 题 :Sulphur-comprising polyaromatic polyamine that can be used in the synthesis of polyurea
发明人：FEDURCO MILAN; RIBEZZO MARCO
权利人:MICHELIN & CIE; MICHELIN RECH TECH
摘要:A sulphur-comprising polyaromatic polyamine compound can be used as a monomer or prepolymer, when n is different from zero, in the synthesis of polyurea. The compound corresponds to the formula (I):n nH 2 N—Ar 1 —NH—CH 2 —CH(OH)—(CH 2 ) m —O—Z 1 —O—(CH 2 ) m —CH(OH)—CH 2 —[X] n —HN—Ar 2 —NH 2 n nin which X represents the string:n n—HN—Ar 3 —NH—(CH 2 )—CH(OH)—(CH 2 ) m —O—Z 2 —O—(CH 2 ) m —CH(OH)—(CH 2 )—n nand in which n represents an integer equal to zero or different from zero; m, which are identical or different, represent an integer within a range from 1 to 10; Z 1 and Z 2 , which are identical or different, represent a divalent bonding group comprising from 1 to 30 carbon atoms; and Ar 1 , Ar 2 and Ar 3 , which are identical or different, each represent a phenylene group, at least one of these phenylene groups bearing one, two, three or four groups of formula —S x —R in which “x†is an integer from 1 to 8 and R represents hydrogen or a hydrocarbon group which can comprise a heteroatom and which comprises from 1 to 10 carbon atoms.

专利号:US-7812193-B2
优先权日:2003-09-19
标题:Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation
发明人：REBIERE FRANCOIS; DURET GERARD; PRAT LAURENCE
权利人:CEPHALON FRANCE
摘要:The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of:n a) contacting a pro-chiral sulphide of formula (II) with a metal chiral complex, a base and an oxidizing agent in an organic solvent; and optionally b) isolating the obtained sulphoxide of formula (I); nn nwherein n, Y, R 1 , R 1a , R 2 and R 2a are as defined herein.

专利号:US-2010022549-A1
优先权日:2008-07-23
标题 :Alpha-helix mimetic with functionalized pyridazine
发明人：REBEK JR JULIUS; MOISAN LIONEL; CARELLA ALEXANDRE; MANN ENRIQUE
权利人:SCRIPPS RESEARCH INST
摘要:The synthesis of new α-helix scaffolds mimicking i, i+3 or i+4, i+7 residues, was accomplished. The common pyridazine heterocycle originates from the easily available dimethyl pyridazine-3,6-dicarboxylate building block. These scaffolds may be thought of as synthetic counterparts of amphiphilic α-helices having a hydrophilic face along one side and a hydrophobic face along the other side of the helix.

专利号:US-2005222257-A1
优先权日:2003-09-19
标题:Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation

专利号:US-2007117154-A1
优先权日:1999-10-04
标题 :Combinatorial Synthesis of Libraries of Macrocyclic Compounds Useful in Drug Discovery