专利号:US-8354524-B2 优先权日:2001-03-22 标 题:Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids 发明人:HUANG ZHEN 权利人:UNIV GEORGIA STATE RES FOUND; HUANG ZHEN 摘要:The present invention provides selenium derivatives of nucleosides, nucleoside phosphoramidites, nucleotides, nucleotide triphosphates, oligonucleotides, polynucleotides, and larger nucleic acids and methods for their synthesis. Selenium derivatives of both ribonucleic acids and deoxyribonucleic acids, as well as methods for their synthesis, crystallization and uses in structural determinations, particularly by X-ray crystallographic techniques are disclosed. The selenium derivatives of the present invention are also useful as food supplements.
专利号:US-11560357-B2 优先权日:2018-09-22 标题 :Methods of producing pyrazole compounds 发明人:GUPTA RAMESH CHANDRA; SINGARAVEL MOHAN; CHHIPA LAXMIKANT; KASUNDRA ASHOK 权利人:TORRENT PHARMACEUTICALS LTD 摘要:The present invention is directed to methods of producing substituted pyrazole based compounds through novel intermediates and unique processes for preparing such intermediates which enables synthesis of final product through commercially viable route of synthesis. The present invention is also directed to novel methods of producing substituted pyrazole based thyroid like compounds, and solid forms of 3-{4-[(7-hydroxy-6-methyl-indan-4-yl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-propanoic acid, its pharmaceutical compositions, and methods of preparation thereof.
专利号:US-2003055016-A1 优先权日:2001-03-22 标 题:Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids
专利号:EP-3567040-B1 优先权日:2013-06-24 标 题 :Method for the preparation of intermediates useful for the synthesis of [1,2,4]-triazolo[4,3-a]pyridines
专利号:EP-3567040-A1 优先权日:2013-06-24 标题 :Method for the preparation of intermediates useful for the synthesis of [1,2,4]-triazolo[4,3-a]pyridines
专利号:US-2012065387-A1 优先权日:2001-03-22 标题:Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids
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合成参考文献
摘要:Evano, G., Science of Synthesis, (2007) 20, 147.