CAS: 654-53-5; 2,3,4,5-Tetrafluorobenzotrifluoride

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CAS号115812-33-4 2,3,4-trifluoro... | CAS号97985-54-1 2,3,4,5-四氯三氟甲苯 | CAS号2751-90-8 四苯基溴化磷 | CAS号715-30-0 Benzene,1-chlor... | CAS号19113-94-1 Perfluorofluorene | CAS号66820-64-2 2-溴-3,4,5,6-四氟三氟甲苯

2,3,4,5-四氯三氟甲苯置于potassium Fluoride,(N,N-Dimethylimidazolidino)-Tetramethylguanidinium Chloride体系中,用 二氯甲烷 作为反应溶剂,化学反应 34.0H,以84%的收率获得产物2,3,4,5-四氟三氟甲苯
参考文献:Halex Reactions Of Aromatic Compounds Catalysed By 2-Azaallenium,Carbophosphazenium,Aminophosphonium And Diphosphazenium Salts: A Comparative Study
标题:Halex Reactions Of Aromatic Compounds Catalysed By 2-Azaallenium,Carbophosphazenium,Aminophosphonium And Diphosphazenium Salts: A Comparative Study
摘要:An Increasing Number Of Biologically Active Compounds In The Pharma And Agro-Chemical Sector Contain Carbon Fluorine Bonds. One Of The Most Common Methods To Introduce Fluorine Into Intermediates Is The Well-Investigated Halogen-Exchange Reaction,In Which Chloro-And Bromoaromatics Activated Towards Nucleophilic Substitution,React With A Fluoride Source To Yield The Corresponding Fluoroarenes. In General,The Reaction Is Supported By Phase-Transfer Catalysts. The Use Of A New Class Of Very Active Phase-Transfer Catalysts Gives The Possibility Of Substituting Even Halogens With Weak Activation Giving A Convenient Access To Interesting Compounds That Are Not Available So Far And Opening Up New Synthetic Routes In Halex Chemistry. Our New Classes Of Catalysts,Cnc+ (1A),Pnc+ (2A) And Several Different Approaches Presented By Other Groups Are Described And Experimental Results Discussed. (C) 2004 Published By Elsevier B.V.
DOI:10.1016/j.Jfluchem.2004.01.030