CAS: 66171-50-4; Methyl 6-Hydroxynicotinate

相似化合物

5006-66-6 26218-80-4 66909-31-7

上下游产品

CAS号67-56-1 甲醇 | CAS号5006-66-6 6-羟基烟酸 | CAS号18107-18-1 (三甲硅烷)重氮甲烷 | CAS号26218-80-4 6-甲氧基烟酸甲酯 | CAS号79-37-8 草酰氯 | CAS号10561-91-8 1-甲基-6-氧代-1,6-二... | CAS号104941-01-7 methyl 1-[3-(4-... | CAS号381247-99-0 5-溴-6-羟基烟酸甲酯 | CAS号56055-54-0 5,6-二氯烟酸甲酯 | CAS号73781-91-6 6-氯烟酸甲酯 | CAS号365413-29-2 6-氯-5-碘烟酸甲酯 | CAS号1360952-35-7 6-氯-5-(三氟甲基)烟酸甲酯 | CAS号78686-77-8 5-溴-6-氯烟酸甲酯 | CAS号77837-09-3 6-氧代-1-苯基-1,6-二... | CAS号77837-08-2 6-氧代-1-苯基-1,6-二...

香豆灵酸甲酯置于1,8-二氮杂双环[5.4.0]十一碳-7-烯 六甲基二硅氮烷体系中,用 乙腈 作为反应溶剂,化学反应 48.0H,以66%的收率获得产物6-羟基烟酸甲酯
参考文献:Synthese Von 2(1H)-Pyridonen Aus 2H-Pyran-2-Onen
标题:Synthese Von 2(1H)-Pyridonen Aus 2H-Pyran-2-Onen
摘要:从2H-吡喃-2-酮合成2(1H)-吡啶酮 5-取代和4,5-二取代的2(1H)-吡啶酮(13个例子)通过将相应的2H-吡喃-2-酮与六甲基二硅氨或烷基(Trimethylsilyl)胺进行胺化反应,在16%-97%的收率下制备了具有甲醛基,酰基,烷氧羧基和三氟甲基的5位取代基.
DOI:10.1055/s-1991-26600

专利信息

专利号:US-6258323-B1
优先权日:1998-11-16
标题:Apparatus and method used in multiple, simultaneous synthesis of general compounds
发明人：HORMANN ROBERT EUGENE; GILBERT DARYL EUGENE; SIOMA EDWARD MICHAEL
权利人:ROHM & HAAS
摘要:The apparatus and method of the present invention provides for conducting simultaneous multiple synthesis of general compounds, which often takes place under varied uneven conditions requiring heating, cooling, agitation, reagent/solvent additions to the reactor contents at each reaction vessel location, supply and maintenance of inert atmosphere and means to facilitate the reflux of the reactor contents. Thus, it becomes necessary to monitor and control the reaction conditions during the simultaneous multiple synthesis of general compounds. The apparatus allows the user to connect various independently controlling and conveying means to each reaction vessel through multiple ports provided on a stopper mounted on each reaction vessel. The apparatus of the present invention permits user to readily access the reaction vessels without interrupting the reactions occurring in the adjacent reaction vessels. The unique geometry and shape of the stopper allows positioning of multiple ports, while still providing the stopper with a compact size. As a result, a large array of reaction vessels can be accommodated in the device of the present invention without significantly increasing the overall size of the apparatus. Some of the general compounds that can be readily synthesized by the apparatus and the method of the present invention include inorganic compounds as well as organic compounds, such as oligomers, polymers, agricultural chemicals, drugs, peptides and oligonucleotides.