CAS: 86479-06-3; Hexaflumuron

该化合物是作为合成抑制剂的甲状腺类昆虫生长调节器(IGR),它扰乱了目标昆虫的磨合和幼虫发育,使其对白蚁,甲虫和白蚁等害虫有效防治.乙氟烯烃露虫表现出高度选择性,最大限度地减少对非目标生物(包括哺乳动物和有益昆虫)的影响.它的系统性和跨光虫特性加强了在经处理环境中的残留活动.该化合物通常配制成作为农业和结构虫害控制的诱饵或喷雾剂.由于其哺乳动物毒性和环境持久性较低,六氟虫虫是综合虫害管理(IPM)方案中的首选选择.其行动方式降低了虫害群快速抗药性发展的可能性.

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3,5-二氯-4-(1,1,2,2-四氟乙氧基)苯胺 3,5-Dichloro-4-(1,1,2,2-Tetrafluoroethoxy)Benzeneamine 104147-32-2

合成工艺路线路线简述

  • 104147-33-3 + 2008-58-4 = 86479-06-3
    反应条件:1.1 6 H,Reflux
    标题:Synthesis Of Hexaflumuron From Bis(Trichloromethyl) Carbonate
    作者:Guo,Xigang; Et Al
    参考文献:Youjifu Gongye 日期:2009 卷标:(2) 页码:5-6]

    104147-32-2 + 18063-03-1 = 86479-06-3
    反应条件:1.1 Solvents: Xylene1.2 -
    标题:Synthesis Of Hexaflumuron By Phosgene Method
    作者:Zhao,Yonghua; Et Al
    参考文献:Nongyao 日期:2001 卷标:40(11) 页码:16-17]

    104147-32-2 + 18063-03-1 = 86479-06-3
    反应条件:1.1 Solvents: Dichloromethane; 2 H,Reflux1.2 Solvents: Dichloromethane; 1 H,Rt
    标题:Synthesis,Purification And Characterization Of Hexaflumumron As Certified Reference Material
    作者:Zou,Ming-Qiang; Et Al
    参考文献:Fenxi Kexue Xuebao 日期:2005 卷标:21(6) 页码:630-632]

    104147-32-2 = 86479-06-3
    反应条件:1.1 Solvents: Toluene; Rt; Rt -> Reflux2.1 6 H,Reflux
    标题:Synthesis Of Hexaflumuron From Bis(Trichloromethyl) Carbonate
    作者:Guo,Xigang; Et Al
    参考文献:Youjifu Gongye 日期:2009 卷标:(2) 页码:5-6
2,6-二氟苯甲酰异氰酸酯 反应生成 氟铃脲
参考文献:Rigterink,R. H.;Sbragia,R. J.
标题:Rigterink,R. H.;Sbragia,R. J.

海关参考信息

专利信息


专利号:US-6107891-A
优先权日:1999-05-06
标题 :Integrated circuit and method for low noise frequency synthesis
发明人:COY BRUCE H
权利人:APPLIED MICRO CIRCUITS CORP
摘要:An integrated circuit device and method for synthesis of a signal having a desired frequency and low noise. The integrated circuit embodiment of the invention generally includes a phase locked loop (PLL) circuit used in conjunction with a frequency multiplier. Specifically, the integrated circuit embodiment includes a frequency multiplier connected to a first input of a phase detector, a low pass filter connected between the output of the phase detector and the input of a voltage controlled oscillator (VCO), and a frequency divider connected between the output of the VCO and a second input to the phase detector. The frequency multiplier produces a signal having a frequency that is a multiple of the frequency of a reference signal which is connected to the input of the frequency multiplier. For any desired output frequency, use of the multiplier results in a smaller divider ratio 'n' in the PLL, thereby reducing the closed loop noise inside the PLL loop bandwidth. Other embodiments of the invention include a method for low noise frequency synthesis, and a method of low noise frequency synthesis for clocking data onto a SONET OC-48 channel. The invention provides the advantage of frequency synthesis with low noise.

专利号:WO-2025056767-A1
优先权日:2023-09-15
标题 :Process for the preparation of enantiomerically enriched aliphatic amines
发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
权利人:SYNGENTA CROP PROTECTION AG
摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

专利号:US-2016073631-A1
优先权日:2013-03-04
标 题 :Process for the preparation of dihydropyrrole derivatives
发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
权利人:SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) n n n n n n n n n n n n wherein n P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; n R 1 is chlorodifluoromethyl or trifluoromethyl; n R 2 is optionally substituted aryl or optionally substituted heteroaryl; n n is 0 or 1; n including the process comprising n (a-i) reacting a compound of formula II n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; n with nitromethane in the presence a chiral catalyst to give a compound of formula III n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; and n (a-ii) reductively cyclising the compound of formula III to give the compound of formula I. n n n n n The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

专利号:US-9233920-B2
优先权日:2010-06-11
标题 :Process for the preparation of dihydropyrrole derivatives
发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
权利人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS; SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) wherein P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; R 1 is chlorodifluoromethyl or trifluoromethyl; R 2 is optionally substituted aryl or optionally substituted heteroaryl; n is 0 or 1; including the process comprising (a-i) reacting a compound of formula II wherein P, R 1 and R 2 are as defined for the compound of formula I; with nitromethane in the presence a chiral catalyst to give a compound of formula III Wherein P, R 1 and R 2 are as defined for the compound of formula I; and (a-ii) reductively cyclizing the compound of formula III to give the compound of formula I. The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

专利号:US-9769003-B2
优先权日:2011-12-12
标题:Direct synthesis of OFDM receiver clock
发明人:BOGDAN JOHN W
权利人:BOGDAN JOHN W
摘要:This application presents a direct data recovery from subspaces or parameters subranges of a received OFDM signal preidentified as corresponding to specific data symbols, by applying adaptive inverse signal transformation (AIST) method for reversing both original data coding and deterministic and random distortions introduced by a transmission channel, wherein both reversals are achieved by the same conversion of the subspaces or parameter subranges into data transmitted originally in order to eliminate an intermediate recovery of signals or parameters transmitted originally within the received OFDM signal. The AIST includes using both amplitudes and gradients of amplitudes of OFDM tone signals.

专利号:US-8293797-B2
优先权日:2004-02-19
标题:Use of molt-accelerating compounds, ecdysteroids, analogs thereof, and chitin synthesis inhibitors for controlling termites
发明人:SU NAN-YAO; KING JAMES EDWARD; NEESE PAUL ALLEN
权利人:SU NAN-YAO; KING JAMES EDWARD; NEESE PAUL ALLEN; UNIV FLORIDA
摘要:The subject invention relates in part to the oral administration of ecdysteroids for controlling subterranean termites. Preferred ecdysteroids for use according to the subject invention are ecdysone, certain ecdysone analogs, and 20-hydroxyecdysone, for example. In some preferred embodiments, one or more of these compounds is used in a termite bait in combination with one or more chitin synthesis inhibitors. Thus, the subject invention also relates in part to controlling termites by the use of a chitin synthesis inhibitor (CSI), such as hexaflumuron and/or noviflumuron, together with an ecdysteroid (and analogs thereof) or molt-accelerating compound (MAC), such as halofenozide. The subject invention also relates to mixtures comprising these two active ingredients. The MAC/ecdysteroid analog induces a preliminary molting event in termite workers (they could not complete the molting), which then allows the CSI to further disrupt the molt and cause mortality. The combination of these active ingredients, causing accelerated molting together with inhibition of chitin synthesis, is surprisingly shown herein to enhance activity against termites, as compared to either group of compounds alone.
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主要参考文献


1: Wang X, Xiang X, Yu H, Liu S, Yin Y, Cui P, Wu Y, Yang J, Jiang C, Yang Q. Monitoring and biochemical characterization of beta-cypermethrin resistance in Spodoptera exigua (Lepidoptera: Noctuidae) in Sichuan Province, China. Pestic Biochem Physiol. 2018 Apr;146:71-79. doi: 10.1016/j.pestbp.2018.02.008. Epub 2018 Mar 2. doi: 10.1002/jssc.201701197. Epub 2018 Jan 31. doi: 10.1002/jssc.201700464. Epub 2017 Aug 1. doi: 10.1016/j.pestbp.2015.12.003. Epub 2015 Dec 8. doi: 10.1016/j.foodchem.2015.11.107. Epub 2015 Nov 27. doi: 10.1016/j.pestbp.2015.05.007. Epub 2015 May 27. doi: 10.1002/jssc.201500970. Epub 2015 Dec 11. doi: 10.1002/jssc.201500714. Epub 2015 Dec 7. doi: 10.1093/jee/tov144. Epub 2015 Jun 6. doi: 10.1093/jee/tou039. Epub 2015 Jan 24. doi: 10.1016/j.exppara.2015.06.011. Epub 2015 Jun 24. doi: 10.1016/j.etap.2014.12.015. Epub 2014 Dec 31. doi: 10.3109/14756366.2014.954107. Epub 2014 Nov 6. doi: 10.1002/ps.3913. Epub 2014 Nov 7. Review. doi: 10.1673/031.014.104.
16: Yang M, Zhang P, Hu L, Lu R, Zhou W, Zhang S, Gao H. Ionic liquid-assisted liquid-phase microextraction based on the solidification of floating organic droplets combined with high performance liquid chromatography for the determination of benzoylurea insecticide in fruit juice. J Chromatogr A. 2014 Sep 19;1360:47-56. doi: 10.1016/j.chroma.2014.07.076. Epub 2014 Aug 1. doi: 10.1111/php.12314. Epub 2014 Aug 12. doi: 10.1016/j.chroma.2014.06.032. Epub 2014 Jun 18. doi: 10.1016/j.pestbp.2014.04.001. Epub 2014 Apr 18. doi: 10.1016/j.foodchem.2013.08.027. Epub 2013 Aug 14.

合成参考文献


摘要:Pesticide Manual., 9(471), 1991
摘要:Franke C et al; Chemosphere 29: 1501-14 (1994)
摘要:U.S. Environmental Protection Agency/Office of Pesticide Program's Chemical Ingredients Database on Hexaflumuron (86479-06-3). Available from, as of June 26, 2002:
摘要:U.S. Environmental Protection Agency/Office of Pesticide Program's Chemical Ingredients Database on Hexaflumuron (86479-06-3). Available from, as of April 23, 2003:
摘要:Tomlin CDS, ed; The Pesticide Manual World Compendium. 11th ed, Surrey, England: British Crop Protection Council, p. 676 (1997)
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