相似化合物
55362-80-6 41059-02-3 29823-18-5欧盟法规
ECHA物质C&L通报上下游产品
ethanol 9-bromononanoic acid monoethyl sebacate 1,7-dibromoheptane-dodecansaeure-(1)-methylester12-2-Carbomethoxy-phenyl-dodecansaeure-(1)-methylester 9-[3-(2,4-diamino-pyrimidin-5-ylmethyl)-4-methoxy-phenoxy]-nonanoic acid ethyl ester triphenylphosphonium bromide8-(ethoxycarbonyl)°Ctyltriphenylphosphonium bromide 9-(6-Oxo-3,4-diphenyl-6H-pyridazin-1-yl)-nonanoic acid 癸二酸氢乙酯 反应生成9-溴壬酸乙酯
参考文献:抗生素及相关物质研究.十二. 10-Oxo-11-Dodecenoic Acid 和 11-Oxo-12-Tridecenoic Acid 抗肿瘤物质的合成
标题:抗生素及相关物质研究.十二. 10-Oxo-11-Dodecenoic Acid 和 11-Oxo-12-Tridecenoic Acid 抗肿瘤物质的合成
摘要:1) 11-Oxo-12-Tridecenoic Acid (Ixa) 由 9-Bromononanoate (II) 通过 11-Oxododecanoic Acid (Iva) 和相应的曼尼希碱 Va. 2) 10-Oxo-11-Dodecenoic Acid ( Ixb) 由 10-氧代十一烷酸 (Ivb) 通过相应的曼尼希碱 Vb 制备.3)已经发现ixa和ixb具有抗肿瘤和抗真菌活性.
Doi:10.1246/bcsj.34.308
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专利信息
专利号:US-9963476-B2
优先权日:2015-02-19
标题 :Antioxidant compound having anti atherosclerotic effect and preparation thereof
发明人:SRIGIRIDHAR KOTAMRAJU; SANTOSH KARNEWAR; BABU VASAMSETTI SATHISH; KUMAR TOGAPUR PAVAN; Reddy Basi Venkata Subba; Kumar Jerald Mahesh
权利人:COUNCIL SCIENT IND RES
摘要:The present invention relates to an antioxidant compound having anti atherosclerotic effect and preparation thereof. The present invention more particularly relates to the synthesis of TPP+ coupled esculetin (mitochondria-targeted esculetin [Mito-Esc]) followed by the biological evaluation of Mito-Esc for its ability to attenuate Angiotensin-II-induced atherosclerosis in apolipoproteinE knockout (ApoE −/− mice along with the endothelial cell age-delaying effects of Mito-Esc.