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CAS号50-00-0 甲醛 | CAS号109-86-4 乙二醇甲醚 | CAS号75-11-6 二碘甲烷 | CAS号3970-21-6 2-甲氧基乙氧基甲基氯 | CAS号7664-93-9 硫酸 | CAS号3970-21-6 2-甲氧基乙氧基甲基氯 | CAS号1768-64-5 4-氯四氢-2H-吡喃合成工艺路线路线简述
- 合成目标产物 Bis(2-Methoxyethoxy)Methane 主要起始原料 Formaldehyde And 2-Methoxyethanol
- (文献来源)合成步骤主要原料 Formaldehyde 和 2-Methoxyethanol
乙二醇甲醚 反应生成 双(2-甲氧基乙氧基)甲烷
参考文献:Nikolic,Nikola A.;Gonda,Elizabeth;Longford,C. P. Desmond;Lane,Nancy T+,J. Org. Chem.,54,(1989) N1,C. 2748-2751
标题:Nikolic,Nikola A.;Gonda,Elizabeth;Longford,C. P. Desmond;Lane,Nancy T+,J. Org. Chem.,54,(1989) N1,C. 2748-2751
专利信息
专利号:US-2024308991-A1
优先权日:2021-01-15
标 题:Process for the synthesis of reactive carbohydrates including antigen precursors for conjugation with a carrier material
发明人:SHIAO TZE CHIEH; MIGNANI SERGE; MOFFETT SERGE; VISHWAKARMA RAM
权利人:KORANEX CAPITAL
摘要:Carbohydrate of Formula (A)where R1 is H and n an integer from 1 to 5, is synthesized by reacting, under heating, compound (A0)with HO—(CH2)n—CHâ•?CH2 in the presence of an acid capable of liberating a proton, and cooling the reaction mixture to obtain a cooled mixture comprising compound (A).Carbohydrate of Formula (AAPG)where R2 is a monovalent protecting group, PG is a divalent protecting group and n an integer from 1 to 5, is synthesized by reacting, in the presence of a metal-containing zeolite, compound of Formula (APG)with compound of Formula (A1)where X is —I, —Br, —Cl, —CN, —OTf (Triflate), —OMs (Mesylate), —OTs (Tosylate), methylsulfate, or trichloroacetimidate. Deprotection of compound (AAPG) forms compound (AA)Carbohydrates (A) and (AA) can be coupled with a thiolated linker to form glycoconjugate precursors, which in turn are conjugatable with a carrier material such as a protein, peptide or polypeptide.
专利号:US-5637775-A
优先权日:1994-04-28
标 题 :Process for the preparation of halogenated ethers
发明人:GALLEGRA PASQUALE; DEGISCHER GERHARD
权利人:SCHWEIZERHALL SAEUREFAB
摘要:The invention relates to a process for the preparation of compounds of formula I (I) wherein R is mono- or disubstituted lower alkyl, the substituents being selected from halogen and lower alkoxy, with the proviso that said substituents are not present at the carbon atom of the lower alkyl radical R linking the group R to the remainder of the molecule of formula I; R1 is hydrogen, lower alkyl, phenyl or phenyl-lower alkyl; and X is chloro or bromo; which comprises reacting an acetal of formula II, (II) wherein R and R1 are as defined above, with at least one compound of formula R2-X, wherein R2 is hydrogen or X-SO, in which last mentioned case the reaction mixture must contain a catalytically effective amount of N,N-di-lower alkyl-lower alkanoylamide(s) and wherein X is as defined with respect to the compounds of formula I. The compounds of formula I are useful intermediates, suitably for the synthesis of pharmaceutical or fungicidal compounds.
专利号:CN-116981678-A
优先权日:2021-01-15
标题 :Methods for the synthesis of reactive carbohydrates including antigen precursors for conjugation to carrier materials
专利号:EP-4277914-A1
优先权日:2021-01-15
标题 :Process for the synthesis of reactive carbohydrates including antigen precursors for conjugation with a carrier material
专利号:US-10647822-B2
优先权日:2015-08-31
标题:Process for preparing organosilicon compounds containing organyloxy groups
发明人:PRASSE MARKO; OSTENDORF DETLEV
权利人:WACKER CHEMIE AG
摘要:Synthesis of organyloxyfunctional organosilicon compounds is facilitated by a two-step process using a basic lithium, guanidine or amidine catalyst in the first step, and a phosphorus compound having a Pâ•?O linkage in a second step.
专利号:CA-3167086-A1
优先权日:2021-01-15
标题 :Process for the synthesis of reactive carbohydrates including antigen precursors for conjugation with a carrier material