专利号:US-2020148541-A1 优先权日:2017-06-01 标题 :An approach to a bottom-up synthesis of nanocarbons 发明人:GIDRON ORI; PHATANGARE SUNITA; DISHI OR; BEDI ANJAN 权利人:YISSUM RES DEV CO OF HEBREW UNIV JERUSALEM LTD 摘要:Provided is a method for the synthesis of a Ï€-conjugated system from oligofurans, under conditions involving cycloaddition.
专利号:US-9422321-B2 优先权日:2010-09-07 标题 :Pyrimidine nucleoside derivatives, synthesis methods and uses thereof for preparing anti-tumor and anti-virus medicaments 发明人:CHANG JUNBIAO; AN HAOYUN; YU XUEJUN; GUO XIAOHE 权利人:CHANG JUNBIAO; AN HAOYUN; YU XUEJUN; GUO XIAOHE; HIGH & NEW TECH RES CENTER HENAN ACAD OF SCIENCES; ZHENGZHOU GRANLEN PHARMATECH LTD; UNIV ZHENGZHOU 摘要:The present invention relates to the field of pharmacochemistry. Disclosed are fluorinated and azido-substituted pyrimidine nucleoside derivatives, particularly compounds of the formula shown below: n nAlso disclosed are methods of preparation and uses for these compounds. The compounds can be used for preparing medicaments for treating diseases such as tumors and viral infections, and can be used separately or in combination with other medicaments. The compounds also have effective activity against diseases such as tumors and viral infections, while having few side effects, and thus have potential application value.
专利号:WO-2018220634-A1 优先权日:2017-06-01 标 题 :An approach to a bottom-up synthesis of nanocarbons
专利号:WO-03061385-A1 优先权日:2002-01-17 标题:Tricyclic nucleoside library compounds, synthesis, and use as antiviral agents 发明人:AN HAOYUN; HONG ZHI; SMITH KENNETH; DING YILI; GIRARDET JEAN-LUC 权利人:RIBAPHARM INC; AN HAOYUN; HONG ZHI; SMITH KENNETH; DING YILI; GIRARDET JEAN-LUC 摘要:Tricyclic nucleoside libraries and library compounds are prepared using combinatorial chemistry and non-combinatorial chemistry methods. Contemplated library compounds are particularly useful in inhibition of viral propagation, and particularly of viral propagation of the HCV virus.
专利号:EP-1658282-B1 优先权日:2003-08-29 标题:Novel chelating agents and chelates and their use 发明人:HOVINEN JARI; MUKKALA VELI-MATTI; HAKALA HARRI; PEURALAHTI JARI 权利人:WALLAC OY 摘要:This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relates to novel chelating agents useful in solid phase synthesis of oligonucleotides or oligopeptides and the oligonucleotides and oligopeptides so obtained.
专利号:US-7157604-B2 优先权日:2001-08-13 标题:Selective estrogen receptor modulators 发明人:MENG DONGFANG; PARKER JR DANN LEROY; WILKENING ROBERT R; RATCLIFFE RONALD W 权利人:MERCK & CO INC 摘要:The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a variety of conditions related to estrogen functioning including: bone loss, bone fractures, osteoporosis, cartilage degeneration, endometriosis, uterine fibroid disease, hot flashes, increased levels of LDL cholesterol, cardiovascular disease, impairment of cognitive functioning, cerebral degenerative disorders, restenosis, gynecomastia, vascular smooth muscle cell proliferation, obesity, incontinence, and cancer, in particular of the breast, uterus and prostate.