CAS: 120013-45-8; Donepezil Impurity 3

相似化合物

120014-07-5 923571-20-4 130927-68-3

上下游产品

二氢多奈哌齐 1-Benzyl-4-[(5,6-Dimethoxy-1-Indanol)-2-Yl]Methylpiperidine 120012-04-6
多萘哌齐碱 Donepezil 120014-06-4

二氢多奈哌齐置于盐酸体系中,用 水 用作溶剂,化学反应 1.0H,反应生成1-苄基-4-(5,6-二甲氧基-1H-2-茚基甲基)哌啶
参考文献: Crystalline Form Of Donepezil Hydrochloride[fr] Forme Cristalline D'Hydrochlorure De Donepezil
标题: Crystalline Form Of Donepezil Hydrochloride[fr] Forme Cristalline D'Hydrochlorure De Donepezil

专利信息

专利号:US-2009298879-A1
优先权日:2006-05-18
标 题 :Impurities of Donepezil
发明人：KRIZMANIC IRENA; LERMAN LIDIJA; SAMARDZIC ZRINKA; KACZOROWSKA KATARZYNA; MANIKOWSKI ANDRZEJ; ZIORO BARBARA; GREBENAR IVICA; KORUZNJAK JASNA DOGAN
权利人:PLIVA HRVATSKA D O O
摘要:The present invention relates to impurities of donepezil, or a pharmaceutically acceptable salt thereof, which may be produced during synthesis and storage of donepezil, or a pharmaceutically-acceptable salt thereof, and to methods of identifying such impurities. The invention also relates to the use of these impurities in analytical techniques and to product that contain certain low levels of these impurities in particular the following impurities are disclosed: formula (I) and formula (II).