CAS: 127-91-3; β-Pinene

该化合物是具有化学配方C10H16的双环单体,其特点是其独特的松状芳香,通常与锥形树有关;在室内温度下,它无色可粉黄色液体,其沸点相对较低,使其挥发性. -五氯苯酚在水中溶解,但在乙醇和乙醇等有机溶剂中可溶解.它因其在香味和口味工业中的作用,以及存在于基本油中,特别是松和迷迭香的油中.除了其芳香特性外,它还具有潜在的生物活动,包括抗微生物和抗炎效应.它还被用于各种化学化合物的合成和工业应用中的溶剂.由于它的自然发生和香味,它经常被用于香水,化妆品和食品调味.然而,应当谨慎处理它,因为它可能是一种对以浓缩形式形成的皮肤和呼吸系统具有刺激性.

结构式图片

欧盟法规

欧盟化妆品法规附录三-限用物质清单ECHA物质ECHA物质C&L通报REACH预注册

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合成工艺路线路线简述

    6,6-二甲基-2-亚甲基二环[3.1.1]-3-庚醇置于lithium Aluminium Tetrahydride,氧气,亚甲兰,四氯化钛体系中,用 四氢呋喃,甲醇 用作溶剂,化学反应 38.0H,反应生成Beta-蒎烯
    参考文献:A New Synthesis Of (-)-β-Pinene From (-)-α-Pinene
    标题:A New Synthesis Of (-)-β-Pinene From (-)-α-Pinene
    摘要:
    Doi:10.1055/s-1982-29984

    海关参考信息

    专利信息


    专利号:WO-2024012791-A1
    优先权日:2022-07-11
    标题 :Electrochemical synthesis of pyrazolines and pyrazoles
    发明人:BÄR ROBIN MAXIMILIAN; FORD MARK JAMES; KALDAS SHERIF JAMES; WALDVOGEL SIEGFRIED; HOFMANN SILJA; LINDEN MARTIN
    权利人:BAYER AG
    摘要:The present invention relates to an electrochemical process for the synthesis of pyrazolines and pyrazoles of formula (I). The process can be especially used for the synthesis of the herbicide safener mefenpyr-diethyl.

    专利号:US-11046978-B2
    优先权日:2016-03-16
    标 题:Synthesis of isoprenoids and derivatives
    发明人:GONZALEZ RAMON; CLOMBURG JAMES M; CHEONG SEOKJUNG
    权利人:UNIV RICE WILLIAM M
    摘要:This disclosure generally relates to the use of enzyme combinations or recombinant microbes comprising same to make isoprenoid precursors, isoprenoids and derivatives thereof including prenylated aromatic compounds. Novel metabolic pathways exploiting Claisen, aldol, and acyioin condensations are used instead of the natural mevalonate (MVA) pathway or 1-deoxy-d-xylulose 5-phosphate (DXP) pathways for generating isoprenoid precursors such as isopentenyl pyrophosphate (IPP), dimethylallyl pyrophosphate (DMAPP), and geranyl pyrophosphate (GPP). These pathways have the potential for better carbon and or energy efficiency than native pathways. Both decarboxylative and non-carboxylative condensations are utilized, enabling product synthesis from a number of different starting compounds. These condensation reactions serve as a platform for the synthesis of isoprenoid precursors when utilized in combination with a variety of metabolic pathways and enzymes for carbon rearrangement and the addition/removal of functional groups. Isoprenoid alcohols are key intermediary products for the production of isoprenoid precursors in these novel synthetic metabolic pathways.

    专利号:US-4140708-A
    优先权日:1975-10-16
    标 题 :Asymmetric synthesis of optically active prostaglandins
    发明人:CHADHA NARESH K; PARTRIDGE JR JOHN J; USKOKOVIC MILAN R
    权利人:HOFFMANN LA ROCHE
    摘要:An asymmetric synthesis of optically active prostaglandin F 2 α from cyclopentadiene including intermediates in this synthesis.

    专利号:US-3933892-A
    优先权日:1973-02-12
    标题 :Asymmetric synthesis of optically active prostaglandins
    发明人:CHADHA NARESH KUMAR; PARTRIDGE JR JOHN JOSEPH; USKOKOVIC MILAN RADOJE
    权利人:HOFFMANN LA ROCHE
    摘要:An asymmetric synthesis of optically active prostaglandin F 2 .sub.α from cyclopentadiene including intermediates in this synthesis.

    专利号:US-7429658-B2
    优先权日:2003-09-11
    标题 :Synthesis of protected pyrrolobenzodiazepines
    发明人:HOWARD PHILIP; MASTERSON LUKE
    权利人:SPIROGEN LTD
    摘要:A method of synthesis of a N-10 protected PBD compound of formula (I): n nvia an intermediate of formula (II) or formula (V):

    专利号:US-4727146-A
    优先权日:1980-07-03
    标题 :Synthesis of chiral 1-benzyl-1,2,3,4-tetra-hydroisoquinolines by asymmetric reduction
    发明人:RICE KENNER C
    权利人:US HEALTH
    摘要:In a short total synthesis of morphinan compounds, derivatives of 1-benzyl-1,2,3,4-tetrahydroisoquinoline are produced. Certain of these compounds, although highly aromatic and functionalized, can be optically resolved. The optically active enantiomers can serve as important intermediates for both natural and unnatural opioids. As a special function of this invention, certain of the derivatives, namely 4'-6' and 7'-9', may be hydrogenated to 1'-3' derivative by asymmetric reduction either of the catalytic or chemical type.
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    合成参考文献


    摘要:Zaidlewicz, M.; Krzemiński, M. P.; Dzieleńdziak, A., Science of Synthesis, (2009) 48, 380.
    摘要:Lam, K.; Leech, M. C.; Lennox, A. J. J., Science of Synthesis: Special Topics, (2021) 1, 462.
    参考文献:10.1006/abbi.1999.1467
    摘要:Phillips MA, Savage TJ, Croteau R. Monoterpene Synthases of Loblolly Pine (Pinus taeda) Produce Pinene Isomers and Enantiomers. Archives of Biochemistry and Biophysics. 1999 Dec;372(1):197–204. doi: 10.1006/abbi.1999.1467.
    参考文献:10.1142/s0192415x0400193x
    摘要:Lai EY, Chyau CC, Mau JL, Chen CC, Lai YJ, Shih CF, Lin LL. Antimicrobial activity and cytotoxicity of the essential oil of Curcuma zedoaria. Am J Chin Med. 2004;32(2):281–90. doi: 10.1142/s0192415x0400193x.
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