CAS: 14268-66-7; 3,4-(Methylenedioxy)Aniline

上下游产品

CAS号2620-44-2 3,4-亚甲基二氧化硝基苯 | CAS号1181403-64-4 2-(benzo[d][1,3... | CAS号2635-13-4 1-溴-3,4-(亚甲基二氧基)苯 | CAS号274-09-9 1,2-亚甲二氧基苯 | CAS号7228-38-8 5-氯-1,3-苯并二氧杂环戊 | CAS号1336-21-6 氨水 | CAS号4847-94-3 1,3-苯并间二氧杂环戊烯-5-羧酰胺 | CAS号857829-30-2 2,4-dinitroso-2... | CAS号716-32-5 6-硝基-1,3-苯并二氧代-5-羧酸 | CAS号4421-09-4 洋茉莉腈 | CAS号107583-34-6 5H-[1,3]二氧代lo[4... | CAS号32953-14-3 3,4-亚甲二氧基-N-乙基苯胺 | CAS号571158-97-9 Benzamide, 2-am... | CAS号141991-33-5 N-[4-[(6-chloro... | CAS号94838-82-1 3.4-(亚甲二氧基)苯硼酸频呢醇酯 | CAS号267428-44-4 1-(1,3-苯并二氧-5-基... | CAS号81329-90-0 N-羟乙基-3,4-亚甲二氧基苯胺盐酸盐 | CAS号533-31-3 芝麻酚 | CAS号69922-28-7 3,5-(甲基)苯基异氰酯酯 | CAS号72700-23-3 8-氯-[1,3]二氧戊并[4...

胡椒环置于o-新戊酰羟铵三氟甲磺酸盐,Copper(II) Oxide体系中,用 2,2,2-三氟乙醇 用作溶剂,以66 %的收率获得3,4-亚甲二氧基苯胺
参考文献:铜催化芳烃ch键与羟胺衍生物的伯胺化
标题:铜催化芳烃ch键与羟胺衍生物的伯胺化
摘要:开发了一种利用羟胺衍生物作为氨替代物对芳香族 C(Sp 2 )-H 键进行伯胺化的新方法.利用经济高效且方便的氧化铜,在温和条件下无需外部氧化剂即可合成多种芳香伯胺,且收率中等至非常好.这种胺化表现出优异的官能团耐受性,广泛的底物范围,使用现成的底物以及简便的后处理程序.此外,还允许对结构复杂的类药小分子进行后期修饰.
Doi:10.1016/j.Tetlet.2023.154699

专利信息

专利号:WO-2015198349-A1
优先权日:2014-06-25
标 题 :A one pot synthesis of 3-substituted quinoline carboxylates and its derivatives
发明人：GADAKH SUNITA KHANDERAO; SUDALAI ARUMUGAM
权利人:COUNCIL SCIENT IND RES
摘要:The present invention provides a one pot, simple, cost effective and industrially feasible catalytic synthesis of quinolines or substituted quinolines from anilines with yield >80% yield. The present invention also discloses a process for the synthesis of oxolinic acid using quinolines with yield > 45%.

专利号:US-6262272-B1
优先权日:1997-11-13
标题 :Method of synthesis of pyrrole amides
发明人：RAGAN JOHN ANTHONY; MAKOWSKI TERESA WOODALL; AM ENDE DAVID JON; CLIFFORD PAMELA JANE; YOUNG GREGORY RANDALL; CONRAD ALYSON KAY; EISENBEIS SHANE ALLEN; QUALLICH GEORGE JOSEPH; ALLEN DOUGLAS JOHN MELDRUM
权利人:PFIZER
摘要:A method for preparing pyrrole-carboxyamides which selectively bind to GABAa receptors; which comprises reacting 1,3-cycloakane-diones with bromoethylacetate followed by reaction of the resulting product with an acid halide followed by reaction with an aromatic amine and finally with an amonium source at an elevated temperature.

专利号:US-8778830-B2
优先权日:2010-05-14
标题:Solid supported gold nanoparticles, methods of use thereof, and methods for making same
发明人：CHE CHI-MING; SO MAN-HO
权利人:CHE CHI-MING; SO MAN-HO; UNIV HONG KONG
摘要:Solid-supported gold nanoparticles for use as a catalyst for the synthesis of quinolines from anilines and aldehydes using oxygen as an oxidant are provided. Also provided are a method for the preparation of SiO 2 -supported gold nanoparticles by in situ deposition of gold nanoparticles to silica gel and a method for synthesizing quinolines from anilines and aldehydes using oxygen as an oxidant.

专利号:EP-0332033-A2
优先权日:1988-03-11
标 题:N-cyclopropyl anilines and their use in processes for the synthesis of 1-cyclopropyl-quinolone-carboxylic acids and their derivatives
发明人：SCHRIEWER MICHAEL DR; PETERSEN UWE DR; GROHE KLAUS DR; KREBS ANDREAS DR
权利人:BAYER AG
摘要:N-Cyclopropylanilines of the formula (IV) in which R<1>, X<1>, X<2>, X<3>, A, Z and R<2> have the meaning given in the description, which are suitable for the preparation of 4-quinolone- 3-carboxylic acids, and processes for the preparation of quinolone- carboxylic acid derivatives using N-cyclopropylanilines.

专利号:US-5342947-A
优先权日:1992-10-09
标 题:Preparation of water soluble camptothecin derivatives
发明人：LACKEY Karen; STERNBACH DANIEL D
权利人:GLAXO INC
摘要:The present invention relates to the synthesis of water soluble, camptothecin derivatives of formula (I), (I) wherein: n represents the integer 1 or 2; R1 represents independently, hydrogen, lower alkyl, (C3-7)cycloalkyl, (C3-7)cycloalkyl lower alkyl, lower alkenyl, hydroxy lower alkyl, lower alkoxy lower alkyl; and R2 represents hydrogen and the pharmaceutically acceptable salts thereof.

专利号:US-6849650-B2
优先权日:1998-02-27
标 题:Heterocyclic compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THORSETT EUGENE D; PORTER WARREN J; NISSEN JEFFREY S; LATIMER LEE H; AUDIA JAMES E; DROSTE JAMES
权利人:ATHENA NEUROSCIENCES INC; LILLY CO ELI
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.