丁酸乙酯置于六甲基磷酰三胺,Lithium Diisopropyl Amide体系中,用 四氢呋喃 用作溶剂,化学反应 3.0H,反应生成2-膦酰丁酸三乙脂 参考文献:Synthesis Of .Alpha.-Phosphono Lactones And Esters Through A Vinyl Phosphate-Phosphonate Rearrangement 标题:Synthesis Of .Alpha.-Phosphono Lactones And Esters Through A Vinyl Phosphate-Phosphonate Rearrangement 摘要: Doi:10.1021/jo00281A012
专利号:US-2025305010-A1 优先权日:2022-05-08 标题:Lipid compositions and methods of producing same 发明人:KEREN TOMER; ELLA EZRA; ARGOV-ARGAMAN NURIT 权利人:WILK TECH INTERNATIONAL LTD; YISSUM RES DEV CO OF HEBREW UNIV JERUSALEM LTD 摘要:Provided is a method of increasing lipid synthesis or accumulation in mammary epithelial cells (MECs) culture and optionally secretion therefrom. The method comprising contacting the MECs with an LXR agonist in the presence of a fatty acid to thereby increase lipid synthesis or accumulation and optionally secretion of lipids. Also provided is a method of producing synthetic fat globules, the method comprising: (a) isolating lipid droplets from cells in culture; (b) encapsulating the droplets with a lipid bilayer, thereby producing synthetic fat globules. Also provided are compositions produced thereby.
专利号:CN-112250692-B 优先权日:2015-05-07 标 题 :Macrocyclization reactions useful for the synthesis of halichondrin macrolides, intermediates and other fragments
专利号:CN-119019391-A 优先权日:2024-08-19 标题 :Synthesis method and application of aza-quinolone compound
参考标题:Efficient Synthesis Of 1-Arylquinoxalin-2(1H)-OnesViaCyclocondensation OfN-Aryl-Substituted 2-Nitrosoanilines With Functionalized Alkyl Acetates 作者:Zbigniew Wróbel,Karolina Stachowska,Andrzej Kwast,Agata Gościk,Magdalena Królikiewicz,Robert Pawłowski,Izabela Turska |发布日期:2013.5 摘要:N‐aryl‐substituted 2‐nitrosoanilines (=2‐nitrosobenzenamines) 1, Readily Available By Nucleophilic Substitution Of The Ortho‐h‐atom In Nitroarenes With Arenamines, React With 2‐substituted Acetic Acid Esters In The Presence Of A Weak Base Giving 1‐arylquinoxalin‐2(1H)‐ones (Scheme 2). This Cyclocondensation Allows For The Synthesis Of Compounds 2-4, Unsubstituted At C(3) Or Substituted By Alkyl, Aryl
合成参考文献
摘要:Collier, S. J., Science of Synthesis, (2007) 20, 673.