CAS: 134-83-8; 1-Chloro-4-(Chloro(Phenyl)Methyl)Benzene

上下游产品

(4-chlorophenyl)phenylmethanol hydrogenchloride benzene 4-chlorobenzophenone 4-((4-chlorophenyl)(phenyl)methyl)morpholine 1,4-bis-(4-chloro-benzhydryl)-piperazine chlorcyclizine 1-ethyl-4-(4-chloro-benzhydryl)-piperazine

4-氯二苯基甲烷置于n-氯代丁二酰亚胺,10-甲基-9-均三甲苯基吖啶高氯酸盐体系中,用 二氯甲烷 用作溶剂,化学反应 1.0H,反应生成4-氯二苯氯甲烷
参考文献:通过有机染料(acr +-Mes)和n-氯代琥珀酰亚胺的组合进行可见光催化的苯甲酰ch键氯化反应.
标题:通过有机染料(acr +-Mes)和n-氯代琥珀酰亚胺的组合进行可见光催化的苯甲酰ch键氯化反应.
摘要:通过将作为安全氯源的" N-氯琥珀酰亚胺(ncs)"与作为光催化剂的" Acr +-Mes"相结合,我们在可见光照射下成功实现了苄基c-h键氯化.此外,通过加入甲醇钠可以一锅法将苄基氯平稳地转化为苄基醚.这种温和且可扩展的氯化方法可有效地用于多种甲苯衍生物,尤其是对于缺电子的底物.仔细的机理研究表明,Ncs提供了一个氢抽象剂" N-中心的琥珀酰亚胺基",该基团依赖于acr •-Mes的还原能力来裂解苄基的c-h键.
Doi:10.1021/acs.Joc.0C01000

专利信息

专利号:RU-2196126-C1
优先权日:2001-05-08
标 题 :Method of synthesis of benzhydryl chlorides

专利号:US-8916705-B2
优先权日:2011-10-14
标 题:Procaspase-activating compounds and compositions
发明人：HERGENROTHER PAUL J
权利人:UNIV ILLINOIS; TRUSTEES OF THE UNIVERSITY OF ILLILNOIS BOARD OF
摘要:The invention provides compounds and compositions useful for the modulation of certain enzymes. The compounds and compositions can induce of cell death, particularly cancer cell death. The invention also provides methods for the synthesis and use of the compounds and compositions, including the use of compounds and compositions in therapy for the treatment of cancer and selective induction of apoptosis in cells.

专利号:US-9663482-B2
优先权日:2012-08-03
标 题:Substituted piperazinyl acetohydrazide procaspase-activating compounds
发明人：HERGENROTHER PAUL J; ROTH HOWARD S
权利人:UNIV ILLINOIS
摘要:The invention provides compounds and compositions useful for the modulation of certain enzymes. The compounds are of Formula I n nThe compounds and compositions can induce of cell death, particularly cancer cell death. The invention also provides methods for the synthesis and use of the compounds and compositions, including the use of compounds and compositions in therapy for the treatment of cancer and selective induction of apoptosis in cells.