CAS: 21938-47-6; (2,3-Dichlorophenyl)Hydrazine Hydrochloride

上下游产品

2,3-dichloroaniline N-(2,3-Dichloro-phenyl)-N'-[2,2,2-trifluoro-1-phenyl-eth-(Z)-ylidene]-hydrazine N-[Bis-(4-methoxy-phenyl)-methylene]-N'-(2,3-dichloro-phenyl)-hydrazine 4-{1-[(2,3-Dichloro-phenyl)-hydrazono]-ethyl}-benzonitrile 5-Butyl-4-(2'-cyano-biphenyl-4-ylmethyl)-2-(2,3-dichloro-phenyl)-2H-pyrazole-3-carboxylic acid ethyl ester

2,3-二氯苯胺置于盐酸,Sodium Nitrite体系中,用 甲苯 用作溶剂,化学反应 1.0H,反应生成2,3-二氯苯肼盐酸盐
参考文献:一类取代的吲哚脲衍生物,合成方法及其用途
标题:一类取代的吲哚脲衍生物,合成方法及其用途
摘要:本发明公开了一类取代的吲哚脲衍生物,合成方法及其用途,结构如式i所示,式中,各取代基的定义如说明书中所述.本发明的化合物,能够用作cgas‑sting通路靶向抑制剂,用于炎症性疾病和自身免疫性疾病的治疗.

专利信息

专利号:US-11040938-B2
优先权日:2016-07-27
标 题 :Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts
发明人：MA BING; PAN SHUAI
权利人:SHANGHAI HYBRID—CHEM TECH; SHANGHAI HYBRID CHEM TECH
摘要:The present invention provided a continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts. Diazotization, reduction, acidic hydrolysis and salifying with acids are innovatively integrated together. Using acidic liquids of aniline or substituted aniline, diazotization reagents, reductants and acids as raw materials, phenylhydrazine derivative salts is obtained through the synthesis process, which is a three-step continuous tandem reaction including diazotization, reduction, acidic hydrolysis and salifying. The described synthesis process is a kind of integrated solutions, which is carried out in an integrated reactor. The feed inlets of the integrated reactor are continuously filled with raw materials. In the integrated reactor, diazotization, reduction, acidic hydrolysis and salifying are carried out continuously and orderly, and phenylhydrazine salts or substituted phenylhydrazine salts is obtained in the outlet of the integrated reactor without interruption. The total reaction time is no more than 20 min.

专利号:US-2019152896-A1
优先权日:2016-07-27
标题 :Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts

专利号:CN-107663161-B
优先权日:2016-07-27
标题:A kind of continuous flow synthesis process of phenylhydrazine salt and substituted phenylhydrazine salt

专利号:CN-107793362-B
优先权日:2016-08-30
标 题:Synthesis and application of phenyl pyridazinone derivative