间甲基苯甲醚置于alkaline Aqueous Potassium Permanganate,溴,溶剂黄146体系中,化学反应生成2-溴-5-甲氧基苯甲酸 参考文献:Shah; Bhatt; Kanga,Journal Of The University Of Bombay,Science: Physical Sciences,Mathematics,Biological Sciences And Medicine,1934,Vol. 3/2,P. 155,157 标题:Shah; Bhatt; Kanga,Journal Of The University Of Bombay,Science: Physical Sciences,Mathematics,Biological Sciences And Medicine,1934,Vol. 3/2,P. 155,157
专利号:US-7943723-B2 优先权日:2006-12-21 标 题:Process for the synthesis of ethers of aromatic acids 发明人:RITTER JOACHIM C 权利人:DU PONT 摘要:The inventions disclosed herein include processes for the preparation of an ether of an aromatic acid, processes for the preparation of products into which such an ether can be converted, the use of such processes, and the products obtained and obtainable by such processes. A key feature of the processes described is the use of a solvent comprising an alcohol ROH and an alcoholate RO − M + .
专利号:US-8106031-B2 优先权日:2006-05-02 标题:Hydrolytically-resistant boron-containing therapeutics and methods of use 发明人:LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A 权利人:LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A; ANACOR PHARMACEUTICALS INC 摘要:Compositions and methods of use of boron derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by fungi, yeast, bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.
专利号:US-8207374-B2 优先权日:2006-12-21 标 题:Process for the synthesis of ethers of aromatic acids 发明人:RITTER JOACHIM C 权利人:RITTER JOACHIM C; DU PONT 摘要:Ethers of aromatic acids are produced from halogenated aromatic acids in a reaction mixture containing a copper (I) or copper (II) source and a diketone ligand that coordinates to copper.
专利号:US-2011060118-A1 优先权日:2009-09-02 标 题:Process for the synthesis of fluorinated ethers of aromatic acids 发明人:RITTER JOACHIM C; MOLOY KENNETH GENE; POLLINO JOEL M; MAHAJAN DU SURBHI 权利人:DU PONT 摘要:Fluorinated ethers of aromatic acids are produced from halogenated aromatic acids in a reaction mixture containing a copper (I) or copper (II) source and a Schiff base ligand that coordinates to copper. The fluorinated ethers of aromatic acids made using the process described herein can be applied to, e.g., fibers, yarns, carpets, garments, films, molded parts, paper and cardboard, stone, and tile to impart soil, water and oil resistance. By incorporating the fluorinated ethers of aromatic acids, or diesters thereof, into polymer backbones, more lasting soil, water and oil resistance, as well as improved flame retardance, can be achieved.
专利号:US-7985825-B2 优先权日:2006-12-21 标 题 :Process for the synthesis of ethers of aromatic acids 发明人:RITTER JOACHIM C 权利人:DU PONT 摘要:Ethers of aromatic acids are produced from halogenated aromatic acids in a reaction mixture containing a halogenated aromatic acid such as is described by the structure of Formula II n nwherein each X is independently Cl, Br or I; the reaction mixture further comprising;n (i) a polar protic solvent, a polar aprotic solvent or an alcoholic solvent containing the alcoholate RO-M+ (wherein M is Na or K), wherein the polar protic solvent, polar aprotic solvent or alcoholic solvent is either ROH or is a solvent that is less acidic than ROH; (ii) a copper (I) or copper (II) source; and (iii) an amino acid ligand that coordinates to copper, wherein the ligand comprises an amino acid in which the amine nitrogen and the carboxyl carbon are separated by no more than two carbon atoms.
专利号:US-2011060117-A1 优先权日:2009-09-02 标题:Process for the synthesis of fluorinated ethers of aromatic acids 发明人:RITTER JOACHIM C; MOLOY KENNETH GENE; POLLINO JOEL M; MAHAJAN DU SURBHI 权利人:DU PONT 摘要:Fluorinated ethers of aromatic acids are produced from halogenated aromatic acids in a reaction mixture containing a copper (I) or copper (II) source and a diamine ligand that coordinates to copper. The fluorinated ethers of aromatic acids made using the process described herein can be applied to, e.g., fibers, yarns, carpets, garments, films, molded parts, paper and cardboard, stone, and tile to impart soil, water and oil resistance. By incorporating the fluorinated ethers of aromatic acids, or diesters thereof, into polymer backbones, more lasting soil, water and oil resistance, as well as improved flame retardance, can be achieved.
[参考文献]: Lynn S Adams, Et Al. Pomegranate Ellagitannin-Derived Compounds Exhibit Antiproliferative And Antiaromatase Activity In Breast Cancer Cells In Vitro. Cancer Prev Res (Phila). 2010 Jan;3(1):108-13.
合成参考文献
摘要:Gao, W.-C.; Tian, J., Science of Synthesis Knowledge Updates, (2020) 3, 265. 摘要:Mondal, M.; Bora, U., Science of Synthesis: Metal-Catalyzed Cyclization Reactions, (2016) 2, 527.