CAS: 3154-51-6; N-Formylglycineethylester

该化合物是一种有机化合物,属于氨酸衍生物类别,具有纯氨酸基脊椎,是最简单的氨基酸,经过添加一个气态组和乙酯组的修改,该化合物一般无色,可粉黄黄色液体或固体,视其纯度和形态而定.在水和酒精等极地溶解剂中是溶解的,这是许多氨基酸衍生物的特征.这种甘油衍生物经常用于生物化学研究和合成,因为它们能够参与各种化学反应,包括的形成.形式和乙酯的功能都允许多种再活动,使其在有机合成和药用化学化学中有用.应参考安全数据,以便处理,如所有化学物质一样,确保采取适当的预防措施.

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CAS号623-33-6 甘氨酸乙酯盐酸盐 | CAS号109-94-4 甲酸乙酯 | CAS号107-31-3 甲酸甲酯 | CAS号64-18-6 甲酸 | CAS号52605-49-9 肌氨酸乙酯盐酸盐 | CAS号149-73-5 原甲酸三甲酯 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号2999-46-4 异氰基乙酸乙酯 | CAS号134965-38-1 formic acid,hex... | CAS号2185-07-1 ethyl 2-[(4-nit... | CAS号72030-87-6 5-(4-硝基苯基)恶唑-4-羧酸乙酯 | CAS号74119-32-7 3-Dimethylamino... | CAS号124-40-3 二甲胺 | CAS号75-65-0 叔丁醇 | CAS号74119-33-8 3-Dimethylamino... | CAS号32755-45-6 ETHYL-(1-IS°CYA... | CAS号177760-04-2 2-氨基-1-甲基-1H-咪唑... | CAS号2999-46-4 异氰基乙酸乙酯 | CAS号23012-14-8 4-噁唑羧酸乙酯

合成工艺路线路线简述

    甘氨酸乙酯盐酸盐置于sodium Formate,乙酸酐体系中,用 甲酸 作为反应溶剂,以85%的收率获得产物n-甲酰基甘氨酸乙酯
    参考文献:Bis(Acyloxmethyl)Imidazole Compounds
    标题:Bis(Acyloxmethyl)Imidazole Compounds
    摘要:这项发明涉及新的双(酰氧甲基)咪唑衍生物;包括这些衍生物的组合物;以及作为杀菌剂,杀菌剂和抑制癌症生长的工具的过程,特别是固体肿瘤癌症,在温血动物中的公式:##str1## 其中m是##str2##或r;每个r,R'和r"独立地选自氢和z取代或未取代的烷基,环烷基,环烯烃基,烯基,芳基和杂环戒指,其中所述环至少包括氧,氮,硫或硅中的一个;前提是##str3##可以形成z取代或未取代的杂环,并且连接到咪唑环的r'和r"可以形成z取代或未取代的杂环;x选自氧,硫,氮和烷基中的至少一个;进一步提供的是硅不直接连接到氧,硫或氮,当x为氧或硫时,R'不是氢;z选自卤素,硝基,腈基,烷基,卤代烷基,烯基,羧酸,羧酸酯,羧酸酰胺,醚,硫醚,羟基,酰化羟基,磺酰胺,磺酰脲,亚砜,砜,取代和未取代胺或其混合物.

    海关参考信息

    专利信息


    专利号:US-7737287-B2
    优先权日:2002-03-28
    标 题 :Anomeric derivatives of monosaccharides
    发明人:MEUTERMANS WIM; WEST MICHAEL LEO; GIANG THANH LE; ADAMSON GEORGE; SCHAFER KARL; ABBENANTE GIOVANNI
    权利人:ALCHEMIA LTD
    摘要:This invention relates to combinatorial libraries of potentially biologically active mainly monosaccharide compounds and to methods of preparing same. These compounds are variously functionalized, with a view to varying lipid solubility, size, function and other properties, with the particular aim of discovering a drug or drug-like compound, or compounds with useful properties. The invention provides intermediates, processes and synthetic strategies for the solution or solid phase synthesis of monosaccharides, variously functionalized about the sugar ring, including the addition of aromaticity and charge, and the placement of amino acid and peptide side chain units of isosteres thereof.

    专利号:US-4416817-A
    优先权日:1979-06-08
    标题:3-Methoxy-2-oxoazetidine derivatives and their production
    发明人:MATSUO TAISUKE; OCHIAI MICHIHIKO
    权利人:TAKEDA CHEMICAL INDUSTRIES LTD
    摘要:Novel 3-methoxy-2-oxoazetidine derivatives, which are shown by the following formula wherein R1 is amino, acylated amino or protected amino, are of value as intermediates for the synthesis of useful compounds represented by the formula wherein R1 has the same meaning as defined above, as drugs in the treatment of bacterial infections.

    专利号:US-6982344-B2
    优先权日:2000-10-18
    标 题:Process for preparation of optically active sulfonamides and intermediates for their synthesis
    发明人:IKEMOTO TOMOMI; NISHIGUCHI ATSUKO; TOMIMATSU KIMINORI
    权利人:TAKEDA PHARMACEUTICAL
    摘要:A method including resolution of a diastereomeric mixture represented by the formula n n nwherein R 1 and R 2 are the same or different and each is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, only one of R 1 and R 2 contains one asymmetric carbon, and R a is an optically active and optionally substituted hydrocarbon group or an optically active and optionally substituted heterocyclic group, or a salt thereof, to produce the diastereomer having a steric configuration of the asymmetric carbon for R 1 or R 2 of an R configuration or an S configuration, or a salt thereof.

    专利号:US-10597353-B2
    优先权日:2015-11-11
    标题:Processes for the preparation of diastereomerically and enantiomerically enriched oxazolines
    发明人:BARRECA GIUSEPPE; RASPARINI MARCELLO; CARCONE LUCA; MORANA FABIO
    权利人:QUIM SINTETICA S A
    摘要:The invention relates to an industrially viable and advantageous process for the preparation of (2S,3 R)-2-amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid, having the following formula (I) generally known as Droxidopa, or of intermediates useful in the synthesis thereof.

    专利号:US-2541924-A
    优先权日:1948-09-17
    标 题 :Synthesis of substituted imidazoles
    发明人:JONES REUBEN G
    权利人:LILLY CO ELI

    专利号:ES-2234908-T3
    优先权日:2000-09-14
    标题 :PROCEDURE OF SYNTHESIS OF CHIRAL COMPOUNDS.
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    主要参考文献

    [参考文献]: Luckose F, Et Al. Effects Of Amino Acid Derivatives On Physical, Mental, And Physiological Activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

    合成参考文献


    摘要:Gnanaprakasam, B.; Chaudhari, M. B., Science of Synthesis Knowledge Updates, (2019) 2, 422.
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