专利号:US-11851651-B2 优先权日:2017-06-19 标 题 :Automated methods for scalable, parallelized enzymatic biopolymer synthesis and modification using microfluidic devices 发明人:BANAL JAMES; BERLEANT JOSEPH DON; SHEPHERD TYSON; BATHE MARK 权利人:MASSACHUSETTS INST TECHNOLOGY 摘要:Methods for the automated template-free synthesis of user-defined sequence controlled biopolymers using microfluidic devices are described. The methods facilitate simultaneous synthesis of up to thousands of uniquely addressed biopolymers from the controlled movement and combination of regents as fluid droplets using microfluidic and EWOD-based systems. In some forms, biopolymers including nucleic acids, peptides, carbohydrates, and lipids are synthesized from step-wise assembly of building blocks based on a user-defined sequence of droplet movements. In some forms, the methods synthesize uniquely addressed nucleic acids of up to 1,000 nucleotides in length. Methods for adding, removing and changing barcodes on biopolymers are also provided. Biopolymers synthesized according to the methods, and libraries and databases thereof are also described. Modified biopolymers, including chemically modified nucleotides and biopolymers conjugated to other molecules are described.
专利号:US-6251280-B1 优先权日:1999-09-15 标 题 :Imprint-coating synthesis of selective functionalized ordered mesoporous sorbents for separation and sensors 发明人:DAI SHENG; BURLEIGH MARK C; SHIN YONGSOON 权利人:UNIV TENNESSEE RES CORP; U T BATTELLE LLC 摘要:The present invention relates generally to mesoporous sorbent materials having high capacity, high selectivity, fast kinetics, and molecular recognition capability. The invention also relates to a process for preparing these mesoporous substrates through molecular imprinting techniques which differ from convention techniques in that a template molecule is bound to one end of bifunctional ligands to form a complex prior to binding of the bifunctional ligands to the substrate. The present invention also relates to methods of using the mesoporous sorbent materials, for example, in the separation of toxic metals from process effluents, paints, and other samples; detection of target molecules, such as amino acids, drugs, herbicides, fertilizers, and TNT, in samples; separation and/or detection of substances using chromatography; imaging agents; sensors; coatings; and composites.
专利号:US-6733828-B2 优先权日:2002-01-29 标 题 :Method of fabricating nanostructured materials 发明人:CHAO KUEI-JUNG; YANG CHIA-MIN 摘要:A method of confined synthesis of nanostructured material inside a mesoporous material. The method includes the step of providing mesoporous material having uniform and ordered mesopores. Next, a monolayer of charged functional group is attached on the pore surface of mesoporous host material by reacting with functional molecule. A oppositely-charged molecule is incorporated into the confined space of mesoporous material by either ion exchange or incipient wetness impregnation. Finally, the incorporated molecule is reduced or oxidized or further reacted with secondarily-incorporated molecule to form nanostructured material in mesoporous material.
专利号:US-7785563-B2 优先权日:2005-10-14 标 题:Method of the preparation of microporous crystalline molecular sieve possessing mesoporous frameworks 发明人:RYOO RYONG; CHOI MINKEE 权利人:KOREA ADVANCED INST SCI & TECH 摘要:The present invention relates to a method of preparing a microporous crystalline molecular sieve having mesoporous skeleton, comprising following steps: (a) adding a meso-SDA (meso-Structure Directing Agent) into a gel composition of synthesizing molecular sieve, (b) subjecting the mixture obtained in the above step (a) to crystallization by a hydrothermal reaction, a microwave reaction, a dry-gel synthesis, etc., and (c) removing selectively organic materials from the resulted material obtained in the above step (b) by a calcination or a chemical treatment. Molecular sieve having mesoporous skeleton synthesized by the present invention exhibits, as compared with conventional zeolite, a good molecule diffusion ability and a greatly improved catalytic activity.
专利号:AU-2020226216-A1 优先权日:2019-02-21 标题:Direct nanoemulsion process for the synthesis of spheroidal organosiloxane sub-micron/nanoparticles
专利号:CA-3127541-A1 优先权日:2019-02-21 标 题 :Direct nanoemulsion process for the synthesis of spheroidal organosiloxane sub-micron/nanoparticles
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合成参考文献
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