CAS: 356068-86-5; N-(2-(Diethylamino)Ethyl)-5-Formyl-2,4-Dimethyl-1H-Pyrrole-3-Carboxamide

上下游产品

N-(2-(二乙基氨基)乙基)-2,4-二甲基-1H-吡咯-3-甲酰胺 N-[2-(Diethylamino)Ethyl]-2,4-Dimethyl-1H-Pyrrole-3-Carboxamide 590424-05-8
N-(2-(二乙基氨基)乙基)-5-甲酰基-2,4-二甲基-1H-吡咯-3-甲酰胺 Tert-Butyl 4-[[[2-(Diethylamino)Ethyl]Amino]Carbonyl]-3,5-Dimethyl-1H-Pyrrole-2-Carboxylate 590424-04-7

在 水体系中,用100%的收率获得产物n-(2-(二乙基氨基)乙基)-5-甲酰基-2,4-二甲基-1H-吡咯-3-甲酰胺
参考文献:Amidations Using N,N '-Carbonyldiimidazole: Remarkable Rate Enhancement By Carbon Dioxide
标题:Amidations Using N,N '-Carbonyldiimidazole: Remarkable Rate Enhancement By Carbon Dioxide
摘要:Carbon Dioxide Catalyzes The Reaction Of Imidazolides With Amines To Form Amides. A Substantial Rate Enhancement Is Observed In The Presence Of Co2 Compared To The Co2-Free Case. The Scope And Limitations Of This Reaction Are Discussed.
DOI:10.1021/jo049949K

专利信息

专利号:US-2022356139-A1
优先权日:2019-09-03
标 题:Synthesis of deuterated aldehydes
发明人：WANG WEI
权利人:ARIZONA BOARD OF REGENTS ON BEHALF OF ATHE UNIV OF ARIZONA
摘要:Described are methods for preparing a deuterated aldehyde using N-heterocyclic carbene catalysts in a solvent comprising D 2 O. The methods may be used to convert a wide variety of aldehydes (e.g., aryl, alkyl, or alkenyl aldehydes) to C-1 deuterated aldehydes under mild reaction conditions without functionality manipulation.

专利号:US-11225655-B2
优先权日:2010-04-16
标题:Bi-functional complexes and methods for making and using such complexes
发明人：GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK
权利人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK; NUEVOLUTION AS
摘要:The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.

专利号:US-2011124634-A1
优先权日:2008-05-13
标 题:Bioactive compounds for treatment of cancer and neurodegenerative diseases
发明人：SUN CONNIE L; LI XIAOYUAN
权利人:PONIARD PHARMACEUTICALS INC
摘要:The invention provides bioactive compounds for the treatment of various malconditions such as cancer and neurodegenerative diseases including Alzheimer's disease. The chemical compounds as disclosed herein are found to show bioactivity in bioassays related to these conditions. Pharmaceutical compositions, combinations and methods of synthesis are provided, as are methods of using the compound, compositions and combinations in the treatment of the diseases.

专利号:WO-2021045879-A1
优先权日:2019-09-03
标 题 :Synthesis of deuterated aldehydes