6-三氟甲基-3-吡啶甲醇置于戴斯-马丁氧化剂,Sodium Hydroxide体系中,用 二氯甲烷,乙醚,水 作为反应溶剂,化学反应 1.67H,以45%的收率获得产物6-三氟甲基吡啶-3-醛 参考文献:Piperidines And Related Compounds For The Treatment Of Dementia 标题:Piperidines And Related Compounds For The Treatment Of Dementia 摘要:化合物的化学式i:调节γ-分泌酶的作用,因此可用于治疗阿尔茨海默病及相关疾病.
专利号:US-9745298-B2 优先权日:2015-05-06 标题:Synthesis of a compound that modulates kinases 发明人:IBRAHIM PRABHA N; JIN MASAYOSHI; MATSUURA SHINJI 权利人:PLEXXIKON INC; DAIICHI SANKYO CO LTD 摘要:The present disclosure provides processes for the preparation of a compound of formula I: n nor a salt thereof, active on the receptor protein kinases c-Kit and/or c-Fms and/or Flt3. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I.
专利号:US-2024002405-A1 优先权日:2022-06-01 标题 :Antimicrobial compounds, synthesis methods, and uses thereof 发明人:VERMA RAJNI; DONAVALLI KRISHNA MOHAN; ZAID GENE H 权利人:ANKH LIFE SCIENCES LTD 摘要:Fused tricyclic compounds and novel methods of synthesizing, using, and/or administering the same. Methods of inhibiting microbial activity and/or treating a microbial infection with fused tricyclic compounds, bicyclic compounds, and other polycyclic compounds. The treatment of subjects suffering from a microbial infection comprises the step of administering to the subject one or more fused tricyclic compounds, bicyclic compounds, and other polycyclic compounds or a composition comprising one or more fused tricyclic compounds, bicyclic compounds, and other polycyclic compounds.
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