CAS: 588720-12-1; Ethyl 6-Bromopyrrolo[1,2-C]Pyrimidine-3-Carboxylate

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783302-18-1 107407-80-7 588720-10-9

4-溴-1H-吡咯-2-甲醛,异氰基乙酸乙酯置于1,8-二氮杂双环[5.4.0]十一碳-7-烯体系中,用 二氯甲烷 作为反应溶剂,以53 %的收率获得产物6-溴h-吡咯并[1,2-F]嘧啶-3-甲酸乙酯
参考文献: Compounds For Use In Treating Neurological Disorders[fr] Composés Destinés à être Utilisés Dans Le Traitement De Troubles Neurologiques
标题: Compounds For Use In Treating Neurological Disorders[fr] Composés Destinés à être Utilisés Dans Le Traitement De Troubles Neurologiques
摘要:This Disclosure Provides Compounds Of Formula (I) And Pharmaceutically Acceptable Salts Thereof,That Inhibit Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase 1A (Dyrk1A). These Chemical Entities Are Useful,E.G.,For Treating A Condition,Disease Or Disorder In Which Increased (E.G.,Excessive) Dyrk1A Activation Contributes To The Pathology And/or Symptoms And/or Progression Of The Condition,Disease Or Disorder (E.G.,A Neurological Disorder) In A Subject (E.G.,A Human). This Disclosure Also Provides Compositions Containing The Same As Well As Methods Of Using And Making The Same.