CAS: 766-93-8; N-Cyclohexylformamide

相似化合物

3712-40-1 100-60-7 5817-68-5

上下游产品

sodium formate cyclohexylamine hydr°Chloride cyclohexanone formamideN-methylcyclohexylamine Cyclohexyl is°Cyanide glycyclamide N'-benzoyl-N-cyclohexyl-N-formyl-ureaN'-benzoyl-N-cyclohexyl-N-formyl-urea Amides ( 1-chloro-1-nitr°Cyclohexane cyclohexanone cyclohexylamine 1-nitr°Cyclohexane(Z)-N-benzylidenecyclohexanamine oxide cyclohexyl-ethylidene-amine oxide N-butylidenecyclohexanamine N-oxide cyclohexanone-oxime

环己基异氰酸酯置于二氯二茂锆,Lithium Tri-T-Butoxyaluminum Hydride体系中,用 四氢呋喃,2-甲基四氢呋喃 作为反应溶剂,化学反应 1.0H,以84%的收率获得产物n-环己基甲酰胺
参考文献:化学选择性schwartz试剂介导的异氰酸酯还原为甲酰胺
标题:化学选择性schwartz试剂介导的异氰酸酯还原为甲酰胺
摘要:在广泛可用的异氰酸酯中添加原位产生的schwartz试剂构成了化学选择性,高产且通用的合成各种功能化甲酰胺的方法.立体和电子因素或敏感功能(酯,硝基,腈,烯烃)的存在不会影响该方法的潜力.观测到完全保留了起始材料中所含的立体化学信息.简要研究了甲酰胺在有机金属试剂亲核加成中的应用(chida-Sato烯丙基化,Charette-Huang加到亚氨基三氟甲磺酸酯活化的酰胺中,硼酸酯的matteson同源性).
DOI:10.1021/acs.Orglett.6B01226

专利信息

专利号:US-10364220-B2
优先权日:2012-12-21
标题:Synthesis of succinimides and quaternary ammonium ions for use in making molecular sieves
发明人：SCHMITT KIRK D; ZUSHMA STEPHEN; BURTON ALLEN W
权利人:EXXONMOBIL CHEMICAL PATENTS INC
摘要:The present invention relates to the synthesis of succinimides, in particular to a method for the synthesis of a succinimide compound, comprising the step of reacting an alkyne, with carbon monoxide and ammonia or an amine, in the presence of an iron catalyst, wherein the reaction is carried out in an amine liquid phase and/or in the absence of an ether solvent. The succinimides may be reduced to quaternary ammonium cations which may be used as structure directing agents in the synthesis of molecular sieves.

专利号:US-4111933-A
优先权日:1976-04-30
标题:Protection of functional groups during reaction and their subsequent restoration
发明人：ECKERT HEINER; UGI IVAR; KABBE HANS-JOACHIM
权利人:BAYER AG
摘要:In the process for preparing an organic compound of the formula n n A' -- X n n in which n X is an amino group, a hydroxyl group or a carboxyl group, and n A' is the remainder of the molecule, from an organic compound of the formula n n A -- X n n in which n A is the remainder of the molecule which can undergo reaction to form A', by converting A -- X into a compound of the formula n n A -- Z -- COOR n n in which n Z is --NH--, --O-- or a direct C--C bond, and n R is a radical of the formula ##STR1## IN WHICH Y is a direct C--C single bond, the --CHâ•?CH-- group or an arylene group, n R 1 to R 4 each independently is hydrogen, halogen or an alkyl, aryl, aralkyl, alkoxycarbonyl, alkylaminocarbonyl, arylaminocarbonyl or cycloalkylaminocarbonyl radical, or n R 1 + r 2 and R 3 + R 4 each independently completes a 5- or 6-membered carbocyclic ring, or n R 1 and R 3 conjointly with the grouping --C--Y--C-- forms a carbocyclic ring with 5 or 6 carbon atoms, and Hal is halogen, n Thereby to protect X, then converting A -- Z -- COOR into a compound of the formula n n A' -- Z -- COOR n n and then treating the compound A' -- Z -- COOR to restore the group X, the improvement which comprises effecting the treatment of the compound A' -- Z -- COOR with an alkali metal compound of a complex of monovalent cobalt. The process is applicable particularly to aminocarboxylic acids including intermediates from various stages of the synthesis of penicillins and cephalosporis.

专利号:US-12371398-B2
优先权日:2020-01-24
标题:Method for preparing formamide compounds via hydrogenation of carbon dioxide catalyzed by porous materials
发明人：TU TAO; SHEN YALIANG; ZHENG QINGSHU
权利人:UNIV FUDAN
摘要:A method for preparing formamide compounds via hydrogenation of carbon dioxide catalyzed by porous materials includes the following steps: by taking porous organometallic polymers as catalysts, reacting amine compounds with carbon dioxide and hydrogen under an air atmosphere to prepare formamide compounds. The method has the advantages of high reaction efficiency, good selectivity, mild conditions, economy, environmental protection, and simple operation. The catalysts are solid organometallic polymers with large specific surface area, strong carbon dioxide adsorption, hierarchical pore distribution, and uniformly dispersed metal centers. They are designed and synthesized as the reaction catalysts by changing the proportion of the cross-linked comonomer. The catalysts can be especially used for catalytic synthesis of fine chemical N, N-dimethylformamide (DMF) without addition of any additional solvent, alkali, or other additives, which is convenient for separation and purification of DMF.

专利号:US-3810895-A
优先权日:1971-09-30
标题 :Synthesis of piperazines
发明人：MASSIE S
权利人:UNIVERSAL OIL PROD CO
摘要:PIPERAZINES ARE PREPARED BY REACTING A GLYCOL, AND PARTICULARLY A GLYCOL CONTAINING HYDROXY SUBSTITUENTS ON ADJACENT CARBON ATOMS, WITH AN AMIDE AT ELEVATED TEMPERATURES AND A PRESSURE IN THE RANGE OF FROM ATMOSPHERIC TO ABOUT 300 ATMOSPHERES.

专利号:US-5629394-A
优先权日:1992-12-17
标 题 :Direct synthesis by living cationic polymerization of nitrogen-containing polymers
发明人：CHERADAME HERVE M; CHEN FRANK J; STANAT JON E R; NGUYEN HUNG A; TABAR BEHROOZ R
权利人:EXXON CHEMICAL PATENTS INC
摘要:A method is provided for the direct synthesis by living cationic polymerization of novel polymeric materials functionalized with desirable nitrogen-containing functional groups such as terminal azido, cyano, carbonylamino, cyanato, thiocyanato or thiocarbonylamino groups. Polymerization and functionalization occur in a substantially simultaneous manner. All necessary reactants for the functionalization are present when polymerization is initiated. The nitrogen-containing functional group is provided as a part of a molecule having a release moiety which is preferably resonance stabilized or a tertiary alkyl type and which acts to aid the nitrogen-containing species in functioning as a leaving group.

专利号:US-12187693-B2
优先权日:2018-08-06
标 题:Rapid synthesis method for biomass-based amine
发明人：LI HU; FANG ZHEN; SMITH RICHARD LEE
权利人:UNIV NANJING AGRICULTURAL
摘要:A rapid synthesis method for a biomass-based amine, including: using formamide as an amine source, formic acid as a hydrogen source, and biomass aldehyde or ketone as a raw material, conduct rapid heating promoting direct addition of formamide and aldehyde or ketone compound through microwave-assisted heating and without a solvent and catalyst, and carrying out formic acid reduction preparing and obtaining a corresponding formamide derivative; selectively converting the formamide derivative under the action of a base into a corresponding primary amine through alcoholysis. The microwave-assisted heating reaction system has a significantly higher catalytic efficiency than a corresponding oil bath system, greatly shortens a reaction time, and significantly improves selectivity, where a conversion rate of a biomass aldehyde or ketone compound may reach at least 99%, and a formamide derivative yield may reach 85-99%; the formamide derivative is synthesized to a primary amine through alcoholysis, where a yield may reach 92-99%.