β-环糊精置于iron(Iii) Chloride,乙酸酐,Sodium Methylate体系中,用 甲醇 作为反应溶剂,化学反应生成 麦芽七糖
参考文献:Sweet Block Copolymer Nanoparticles: Preparation And Self-Assembly Of Fully Oligosaccharide-Based Amphiphile
标题:Sweet Block Copolymer Nanoparticles: Preparation And Self-Assembly Of Fully Oligosaccharide-Based Amphiphile
摘要:The Preparation Of Biocompatible Nanocarriers That Have Potential Applications In The Cosmetic And Health Industries Is Highly Desired. The Self-Assembly Of Amphiphilic Block Copolymers Displaying Biosourced Polysaccharides At The Surface Is One Of The Most Promising Approaches. In The Continuity Of Our Works Related To The Preparation Of "Hybrid" Amphiphilic Oligosaccharide-Based Block Copolymers,We Present Here The Design Of A New Generation Of Self-Assembled Nanoparticles Composed Entirely Of Oligosaccharide-Based Amphiphilic Block Co-Oligomers (Bco). These Systems Are Defined By A Covalent Linkage Of The Two Saccharidic Blocks Through Their Reducing End Units,Resulting In A Sweet "Head-To-Head" Connection. As An Example,We Have Prepared And Studied A Bco In Which The Hydrophilic Part Is Composed Of A Free Maltoheptaosyl Derivative Clicked To A Hydrophobic Part Composed Of A Peracetylated Maltoheptaosyl Derivative. This Amphiphilic Bco Self-Assembles To Form Spherical Micelles In Water With An Average Diameter Of 30 Nm. The Efficient Enzymatic Hydrolysis Of The Maltoheptaose That Constitutes The Shell Of The Micelles Was Followed By Light Scattering And Colorimetric Methods.
DOI:10.1021/bm3000138