CAS: 510-20-3; 2,2-Diethylmalonic Acid

上下游产品

二甲基丙二酸 2,2-Dimethylmalonic Acid 595-46-0
二乙基丙二酸二乙酯 Diethyl Diethylmalonate 77-25-8
2-乙基-2-(羟基甲基)丁醛 2-Ethyl-2-(Hydroxymethyl)Butanal 1634-72-6

1-Benzoyl-5,5-Diethyl-Pyrimidine-2,4,6-Trione 反应生成 二乙基丙二酸
参考文献:Melzacka,M.; Kahl,W.,Roczniki Chemii,1971,Vol. 45,P. 1091-1096
标题:Melzacka,M.; Kahl,W.,Roczniki Chemii,1971,Vol. 45,P. 1091-1096

专利信息

专利号:US-2007259917-A1
优先权日:2006-04-24
标题 :Processes for the synthesis of 3-isobutylglutaric acid
发明人：KANSAL VINOD K; CHAURASIA BRIJNATH P; PATEL HITESH K; SHELKE SHIVAJI H; MORE YOGESH P
权利人:KANSAL VINOD K; CHAURASIA BRIJNATH P; PATEL HITESH K; SHELKE SHIVAJI H; MORE YOGESH P
摘要:Provided are processes for the synthesis of 3-isobutylglutaric acid, an intermediate in the synthesis of (S)-Pregabalin.

专利号:US-4288608-A
优先权日:1978-06-01
标题:Synthesis of anthracyclines
发明人：JOHNSON FRANCIS; KIM KYOUNG S
权利人:RESEARCH CORP
摘要:There is provided a novel method of synthesizing certain heterocyclic quinones. In particular there is provided a novel and regiospecific synthesis of 9-acetyl-6,11-dihydroxy-4-methoxy-7,8,9,10-tetrahydronaphthacene-5,12-quinone (7,9-dideoxydaunomycinone) which is known intermediate in the synthesis of daunomycinone. There is also provided a method of preparing analogs of 7,9-dideoxydaunomycinone which thus provide for the preparation of known and desired analogs of daunomycinone. Daunomycinone is a known compound which is an intermediate in the preparation of the clinically accepted naturally-occurring antitumor antibiotics daunomycin and its derivitive adriamycin.

专利号:US-2004266827-A1
优先权日:2003-06-25
标 题 :Convergent asymmetric route to produce a key intermediate towards the synthesis of a garft inhibitor
发明人：NOTZ WOLFGANG REINHARD LUDWIG; MARTINEZ CARLOS ALBERTO
权利人:AGOURON PHARMA
摘要:The invention relates to processes for the preparation of a key intermediate in the synthesis of a GARFT inhibitor of formula (Ia) containing a 4-methyl-substituted thiophene core: n n n wherein said key intermediate has the following formula (I): n n n wherein each of R 1 and R 2 are independently a moiety that together with the attached CO 2 forms a readily hydrolyzable ester group; n from a compound of the formula (VI): n n n wherein R 1 is as described above, Pg 1 is an amino protecting group, and Pg 2 is an ether protecting group; wherein said processes are as described in the specification.

专利号:US-5302520-A
优先权日:1990-09-25
标 题:Enzymatic synthesis of isotopically labeled carbohydrates
发明人：GOUX WARREN J
权利人:UNIV TEXAS
摘要:The present invention relates to a general method of enzymatic synthesis of isotopically labeled carbohydrates, sugars and nucleosides. Labeled citric acid cycle intermediates, amino acids and ribose mononucleotides may be rapidly and conveniently synthesized from labeled pyruvate, lactate or L-alanine. The method employs a novel nicotinamide dinucleotide regeneration system which permits use of low NADH levels. The method may be manipulated to allow labeling at a variety of carbon/hydrogen sites.

专利号:US-4866175-A
优先权日:1966-11-08
标 题 :Novel process for the synthesis of quinoxaline and benzimidazole-N-oxides
发明人：ISSIDORIDES COSTAS H; HADDADIN MAKHLUF J
权利人:RESEARCH CORP
摘要:The synthesis of quinoxaline and benzimidazole-N-oxides and of ester amd amide derivatives of 3-hydroxy-2-quinoxalinecarboxylic acid by a movel process consisting of the reaction between a benzofuroxan and an activated methylene-containing compound under basic conditions.

专利号:US-4014895-A
优先权日:1972-06-22
标 题:Method for synthesis of optically active thiolactones
发明人：AOKI YASUHIKO; SUZUKI HIROYUKI; AKIYAMA HISAO; OKANO SHIGERU
权利人:SUMITOMO CHEMICAL CO
摘要:A new method for the production of intermediates in the synthesis of an optically active biotin, which comprises reacting a dicarboxylic acid of the formula: ##SPC1## n Or its reactive derivative with an optically active primary amine, reducing the resulting trione with a metal hydride, hydrolyzing the resultant amide-alcohol and treating the thus produced lactone with a thiolactonating agent to give a thiolactone of the formula: ##SPC2## n , the said trione and amide-alcohol being respectively novel and representable by the formulae: ##SPC3##