CAS: 583-19-7; 1-Bromo-2-Ethoxybenzene

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CAS号74-96-4 溴乙烷 | CAS号95-56-7 2-溴苯酚 | CAS号75-03-6 碘乙烷 | CAS号103-73-1 苯乙醚 | CAS号597-35-3 二乙砜 | CAS号64-67-5 硫酸二乙酯 | CAS号584-08-7 碳酸钾 | CAS号101251-12-1 3-溴-4-乙氧基苯胺 | CAS号62-44-2 非那西丁 | CAS号22545-14-8 2-(2-ethoxyphen... | CAS号95-56-7 2-溴苯酚 | CAS号6734-91-4 1-ethoxy-2-phen... | CAS号485817-30-9 tris(2-ethoxyph... | CAS号58244-42-1 2-溴-1-乙氧基-4-硝基苯

非那西丁置于盐酸,乙醇体系中,化学反应生成 邻溴苯乙醚
参考文献:Hodurek,Chemische Berichte,1897,Vol. 30,P. 477
标题:Hodurek,Chemische Berichte,1897,Vol. 30,P. 477

专利信息

专利号:EP-1724260-B1
优先权日:2005-05-06
标题:Process for the synthesis of (2S, 3aR, 7aS)octahydroindole-2-carboxylic acid and its conversion to trandolapril
发明人：AKHTAR HAIDER; RAMESH BABU POTLURI; VENKATA SUBHRAMANIAN HARIHARAK; HARI PRASSAD KODALI
权利人:SOCHINAZ SA
摘要:The present invention describes a novel method for the synthesis of (2S,3aR,7aS)-octahydroindole-2-carboxylic acid of formula III nusing a new intermediate of formula II nand conversion of the product of formula-III to trandolapril of formula I

专利号:US-7884125-B2
优先权日:2008-04-30
标 题:Straightforward entry to 7-azabicyclo[2.2.1]heptane-1-carbonitriles and subsequent synthesis of epibatidine analogues
发明人：STEVENS CHRISTIAN; HEUGEBAERT THOMAS
权利人:UNIV GENT
摘要:The present invention relates to a group of substituted-7-azabicyclo-[2.2.1]heptyl derivatives with biological activity. The present invention also relates to synthetic methods for producing said substituted-7-azabicyclo-[2.2.1]heptyl derivatives. The present invention also relates to certain intermediates for producing such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as a synthetic method for producing such intermediates. The present invention also relates to pharmaceutical compositions comprising such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as their use as medicaments for the treatment of diseases mediated by a Nicotinic Acetylcholine Receptor or a receptor being a member of the Neurotransmitter-gated Ion Channel Superfamily, such as pain, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy and nicotine addiction.

专利号:WO-2014170910-A1
优先权日:2013-04-04
标 题:Process for the preparation of lapatinib
发明人：MUDDASANI PULLA REDDY; TALASILA SAMBASIVA RAO; SATTI VENKATA REDDY; NEKKANTI SATISH CHOWDARY; NANNAPANENI VENKAIAH CHOWDARY
权利人:NATCO PHARMA LTD
摘要:Present process relates to an improved and commercial process for the preparation of lapatinib of formula-I or its pharmaceutically acceptable p-toluenesulfonate salt involving novel intermediates of formulae-XVII, XVIII, and XIX. Present process utilizes Meerwein reaction as a key step in the aryl C-C bond formation step avoiding costly boronate coupling chemistry used in the conventional synthesis of lapatinib.

专利号:US-2024175005-A1
优先权日:2021-03-31
标题 :PURIFICATION AND RECYCLING OF mRNA NUCLEOTIDE CAPS
发明人：BEAUDOIN JENNIFER; DIETER LANCE; VIK KAELYN
权利人:MODERNATX INC
摘要:This disclosure relates to purification and recycling nucleotide messenger RNA (mRNA) caps from the preparation of mRNA, which comprises isolating and purifying excess nucleotide mRNA caps from mRNA synthesis.

专利号:US-8026388-B2
优先权日:2008-07-11
标题:Process for making 1-hydroxyalkylidene-1,1-biphosphonic acids
发明人：BARTL JIRI
权利人:SYNTHON BV
摘要:Synthesis of biphosphonate compounds can be advantageously carried out in a solvent/diluent comprising a compound of formula (3) n nwherein R is hydrogen or a C1-C6 alkyl group; each of R1 is a C1-C6 alkyl group or both R1 groups are linked to form a C1-C3 alkylene group; and R2 is hydrogen, a C1-C6 alkyl group, a C1-C6 alkoxy group, or is linked together with R to form a C3-C7 carbon ring.

专利号:US-2009275616-A1
优先权日:2008-04-30
标 题 :Straightforward entry to 7-azabicyclo[2.2.1]heptane-1-carbonitriles and subsequent synthesis of epibatidine analogues