CAS: 6995-79-5; Trans-Cyclohexane-1,4-Diol

该化合物是一种具有僵硬,对称结构,具有独特性能和电子特性的环己二醇,其反形配置可增强热和化学稳定性,使其适合高性能聚合物应用,如聚酯和聚氨酯,其僵化性和抗降解性至关重要.该化合物的两个氢氧化物组为交叉或功能化提供了反应场所,使适应性物质特性成为可能.它与极地溶剂的低挥发性和兼容性进一步扩大了它在涂层,粘合剂和特殊化学品的用途. 环己烷主骨有助于提高机械强度和衍生材料的水力稳定性,使其成为先进的工业配方中有价值的中间体.

英文名称Trans-Cyclohexane-1,4-Diol
中文名称反-1,4-环己二醇
IUPAC名称(1r,4r)-cyclohexane-1,4-diol
其它别名反-1,4-二羟基环己烷; 14环己二醇反式; Trans-1,4-Dihydroxycyclohexane; Cyclohexane-1,4-Diol
CAS编号6995-79-5
MFCD编号:MFCD00063612
分子式:C6H12O2
分子量:116.16
产品CID: 1693960
产品分类有机原料→分子砌块→脂肪环类化合物→环己烷类化合物

相似结构搜索
产品信息参考;;;;
InChIKey: VKONPUDBRVKQLM-IZLXSQMJNA-N
InChI=1S/C6H12O2/c7-5-1-2-6(8)4-3-5/h5-8H,1-4H2/t5-,6-…
计算化学: 氢键受体数2.0氢键供体数2.0可旋转键数0.0

相似化合物

931-71-5 556-48-9 18068-06-9

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H302-H315-H319-H335
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
危险品标志Xn

上下游产品

合成工艺路线路线简述

合成目标产物 Trans-1,4-Cyclohexanediol 主要起始原料 Cyclohexanol
13482-22-9 = 6995-79-5 + 931-71-5
反应条件:1.1 Catalysts: Di-μ-Chlorobis[(1,2,5,6-η)-1,5-Cyclooctadiene]Diiridium,Ferrocene,1-[(1S)-2-[[[(1R)-2,2′-Dihydroxy[1,1′-Binaphthalen]-3-Yl]Methyl]Amino...,Ferrocene,1-[(1R)-2-[[[(1R)-2,2′-Dihydroxy[1,1′-Binaphthalen]-3-Yl]Methyl]Amino...,Ferrocene,1-[(1S)-2-[[[(1R)-2,2′-Dihydroxy[1,1′-Binaphthalen]-3-Yl]Methyl]Amino...,Ferrocene,1-[(1R)-2-[[[(1R)-2,2′-Dihydroxy[1,1′-Binaphthalen]-3-Yl]Methyl]Amino... Solvents: Isopropanol; 2 H,Rt1.2 Reagents: Hydrogen,Lithium Tert-Butoxide Solvents: Ethanol; 12 H,5 Bar,Rt
标题:Pno Ligand Containing Planar Chiral Ferrocene And Axial Chiral Biphenol,And Its Application To Catalyst For Synthesizing Biologically Active Molecular Compound
参考文献:China]

22428-87-1 = 6995-79-5 + 931-71-5
反应条件:1.1 Reagents: Hydrochloric Acid Solvents: Tetrahydrofuran,Water
标题:Synthesis And Biological Evaluation Of Picolinamides As Potent Inhibitors Of 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-Hsd1)
作者:Ryu,Je Ho; Kim,Shinae; Han,Hye Young; Son,Hyun Joo; Lee,Hyun Jung; Et Al
参考文献:Bioorganic & Medicinal Chemistry Letters 日期:2015 卷标:25(3) 页码:695-700]

= 6995-79-5 + 931-71-5
反应条件:1.1 Reagents: Hydrogen Catalysts: Alumina,Platinum,Rhodium,Poly(Dimethylsilylene) (Immobilized Bimetallic Nanocatalyst Support) Solvents: Isopropanol; 49 H,50 °C
标题:Polysilane-Immobilized Rh-Pt Bimetallic Nanoparticles As Powerful Arene Hydrogenation Catalysts: Synthesis,Reactions Under Batch And Flow Conditions And Reaction Mechanism
作者:Miyamura,Hiroyuki; Suzuki,Aya; Yasukawa,Tomohiro; Kobayashi,Shu
参考文献:Journal Of The American Chemical Society 日期:2018 卷标:140(36) 页码:11325-11334]

2641-89-6 = 6995-79-5 + 931-71-5
反应条件:1.1 Reagents: Sodium Hydroxide,Nickel Aluminide Solvents: Water
标题:Reductive Dehalogenation And Ring Saturation Of Halogenated Hydroquinones,Catechol,And Resorcinol With Raney Alloys In Aqueous Sodium Hydroxide
作者:Tsuzuki,Hirohisa; Iyama,Hironobu; Mashimo,Takuya; Mukumoto,Mamoru; Tsukinoki,Takehito; Et Al
参考文献:Chemistry Express 日期:1993 卷标:8(7) 页码:495-8]

637-88-7 = 6995-79-5 + 931-71-5
反应条件:1.1 Reagents: Hydrogen Catalysts: Ruthenium (Supported On Carbon Or Alumina) Solvents: Methanol; 6 H,80 °C
标题:Method For Producing Diols Having Cyclohexane Skeleton Such As Cyclohexanediol Or 1,1'-Bicyclohexyl-4,4'-Diol Having High Trans/cis-Isomer Ratio
参考文献:Japan

1,4-环己二酮在 2,4-二氯苯氧乙酸,Caragana Chamlagu,蔗糖体系中,用水作为反应溶剂,反应 336.0H,以53%的收率获得trans-Cyclohexane-1,4-Diol
参考文献:Biotransformation Of Cycloalkanediones Bycaragana Chamlagu
标题:Biotransformation Of Cycloalkanediones Bycaragana Chamlagu
摘要:使用刀豆(Caragana Chamlagu)悬浮培养细胞对烷基环烷底物进行生物转化,通过氧化断裂生成了氧羧酸.高产率(95%)且在短时间(7小时)内从2-甲基-1,3-环己烷二酮获得了5,6-二氧代庚酸.然而,1,2-和1,4-环烷二酮则被选择性还原,分别获得了顺式-1,2-环己烷二醇和顺式-1,4-环己烷二醇.还讨论了烷基环烷底物氧化断裂的机制.
Doi:10.1246/Bcsj.76.177