CAS: 104-47-2; 4-Methoxyphenylacetonitrile

相似化合物

104-01-8 6343-93-7 6775-77-5

上下游产品

CAS号104-01-8 4-甲氧基苯乙酸 | CAS号31236-71-2 1-甲氧基-4-(2-硝基乙基)苯 | CAS号55-81-2 对甲氧基苯乙胺 | CAS号104-92-7 对溴苯甲醚 | CAS号18293-53-3 (三甲硅基)乙腈 | CAS号10442-39-4 氰化四丁基胺 | CAS号105-13-5 对甲氧基苄醇 | CAS号143-33-9 氰化钠 | CAS号108774-82-9 3,4-bis(4-metho... | CAS号43050-28-8 1-(4-甲氧基苯基)-1-环戊烷甲酸 | CAS号36263-51-1 1-(4-甲氧基苯基)环己烷甲腈 | CAS号491-80-5 鹰嘴豆芽素A | CAS号143504-83-0 3-(4-methoxyphe... | CAS号485-72-3 芒柄花黄素 | CAS号446-72-0 染料木素 | CAS号22102-05-2 4,4,4-TRIFLUORO... | CAS号19781-61-4 cis-4-ethylcycl... | CAS号22102-10-9 1,1,1-trifluoro...

对氨基苯乙腈置于氢氧化钾,Sodium Nitrite体系中,化学反应生成对甲氧基苯乙腈
参考文献:Pschorr; Wolfes; Buckow,Chemische Berichte,1900,Vol. 33,P. 165
标题:Pschorr; Wolfes; Buckow,Chemische Berichte,1900,Vol. 33,P. 165

专利信息

专利号:US-9527800-B2
优先权日:2013-10-29
标 题:Process for total synthesis of venlafaxine
发明人：CHAVAN SUBHASH PRATAPRAO; PAWAR KAILASH PRALHAD
权利人:COUNCIL SCIENT IND RES
摘要:There is a need for short, resolution free asymmetric process for synthesis of one isomer of venlafaxine, (−)-venlafaxine. The invention provides a novel, short process of synthesis of (−)-venlafaxine, with yield greater than 50% and ee>99%. This process can be used for racemic synthesis of venlafaxine with overall yield 65%.

专利号:US-9409855-B2
优先权日:2012-07-25
标 题 :Asymmetric synthesis of (−)-venlafaxine using organocatalyst
发明人：CHAVAN SUBHASH PRATAPRAO; GARAI SUMANTA; PAWAR KAILASH PRALHAD
权利人:COUNCIL SCIENT IND RES
摘要:The patent discloses an asymmetric synthesis of (−)-venlafaxine using an organocatalyst via a unified strategy employing organcatalytic Michael addition, regio-selective dehydration and selective epoxide ring opening.

专利号:US-7605290-B2
优先权日:2006-07-26
标题 :Processes for the synthesis of O-desmethylvenlafaxine
发明人：NIDDAM-HILDESHEIM VALERIE; SHENKAR NATALIA; SHACHAN-TOV SHARONA
权利人:TEVA PHARMA
摘要:The present invention describes processes for the preparation of O-desmethylvenlafaxine and tridesmethylvenlafaxine, which may be used as an intermediate in preparing O-desmethylvenlafaxine.

专利号:US-2009069601-A1
优先权日:2006-07-26
标题:Processes for the synthesis of O-desmethylvenlafaxine
发明人：NIDDAM-HILDESHEIM VALERIE; NIDAM TAMAR; DOLITZKY BEN-ZION
权利人:NIDDAM-HILDESHEIM VALERIE; NIDAM TAMAR; DOLITZKY BEN-ZION
摘要:The present invention describes processes for the preparation of O-desmethylvenlafaxine and tridesmethylvenlafaxine, which may be used as an intermediate in preparing O-desmethylvenlafaxine.

专利号:US-2008221356-A1
优先权日:2006-07-26
标题:Processes for the synthesis of O-desmethylvenlafaxine
发明人：NIDDAM-HILDESHEIM VALERIE; NIDAM TAMAR; DOLITZKY BEN-ZION
权利人:NIDDAM-HILDESHEIM VALERIE; NIDAM TAMAR; DOLITZKY BEN-ZION
摘要:The present invention describes processes for the preparation of O-desmethylvenlafaxine and tridesmethylvenlafaxine, which may be used as an intermediate in preparing O-desmethylvenlafaxine.

专利号:US-2009137846-A1
优先权日:2006-07-26
标题 :Processes for the synthesis of O-Desmethylvenlafaxine
发明人：NIDDAM-HILDESHEIM VALERIE; NIDAM TAMAR; DOLITZKY BEN-ZION; FRENKEL GUSTAVO
权利人:NIDDAM-HILDESHEIM VALERIE; NIDAM TAMAR; DOLITZKY BEN-ZION; FRENKEL GUSTAVO
摘要:The present invention describes processes for the preparation of O-desmethylvenlafaxine and tridesmethylvenlafaxine, which may be used as an intermediate in preparing O-desmethylvenlafaxine.