CAS: 4965-36-0; 7-Bromoquinoline

相似化合物

700871-88-1 4964-71-0 3964-04-3

上下游产品

CAS号333383-82-7 N-(3-bromopheny... | CAS号333383-83-8 N-(3-bromopheny... | CAS号591-19-5 3-溴苯胺 | CAS号7510-48-7 N-(3-溴苯基)-4-甲基苯磺酰胺 | CAS号83922-51-4 N-(3-溴苯基)甲烷磺酰胺 | CAS号56-81-5 甘油 | CAS号4964-76-5 7-甲氧基喹啉 | CAS号851985-81-4 7-(4,4,5,5-四甲基-... | CAS号85656-65-1 7-溴喹啉-8-胺 | CAS号89770-32-1 DIMETHYL-QUINOL... | CAS号443692-93-1 喹啉-7-磺酰氯

N-(3-Bromophenyl)-4-Methyl-Benzenesulfonamide置于三氟甲磺酸,三乙胺体系中,用 甲醇,二氯甲烷 作为反应溶剂,化学反应 0.17H,反应生成 7-溴喹啉
参考文献:Tokuyama,Hidetoshi; Sato,Masashi; Ueda,Toshihiro,Heterocycles,2001,Vol. 54,# 1,P. 105-108
标题:Tokuyama,Hidetoshi; Sato,Masashi; Ueda,Toshihiro,Heterocycles,2001,Vol. 54,# 1,P. 105-108

专利信息

专利号:US-11299484-B2
优先权日:2018-10-10
标 题 :Inhibiting fatty acid synthase (FASN)
发明人：MARTIN MATTHEW W; ZABLOCKI MARY-MARGARET; MENTE SCOT; DINSMORE CHRISTOPHER; WANG ZHONGGUO; ZHENG XIAOZHANG
权利人:FORMA THERAPEUTICS INC
摘要:The present disclosure is directed to inhibitors of FASN. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of FASN. For instance, the disclosure is concerned with compounds and compositions for inhibition of FASN, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of FASN, and methods of synthesis of these compounds.

专利号:CN-118146153-A
优先权日:2024-02-28
标 题 :Synthesis of bicyclo[1.1.1]pentane-1-acid and amine derivatives

专利号:WO-9531458-A1
优先权日:1992-10-13
标 题:3-hydroxyquinuclidin-3-ylphenylquinolines as squalene synthase inhibitors
发明人：NEUENSCHWANDER KENT W; GRONEBERG ROBERT D; MORRIS ROBERT L; SCOTESE ANTHONY C; MAGUIRE MARTIN P
权利人:RHONE POULENC RORER PHARMA; NEUENSCHWANDER KENT W; GRONEBERG ROBERT D; MORRIS ROBERT L; SCOTESE ANTHONY C; MAGUIRE MARTIN P
摘要:This invention relates to a class of novel compounds useful in the treatment of diseases associated with undesirable cholesterol levels in the body, and particularly diseases of the cardiovascular system, such as atherosclerosis. The compounds of this invention are novel quinolinyl phenyl 3-hydroxyquinuclidines which may be linked directly or through a chain linking the quinolinyl to the phenyl and/or the phenyl to the quinuclidine. Compounds of this invention exhibit squalene synthase inhibition properties and reduce levels of serum cholesterol without significantly reducing mevalonic metabolite synthesis and thus provide a therapeutic agent having fewer side effects than agents which act by inhibiting the HMG-CoA reductase enzyme. Compounds of the present invention may also be useful in treating fungal infections. This invention further relates to pharmacological compositions and method of treatment for lowering serum cholesterol levels using the compounds of this invention.

专利号:US-7897774-B2
优先权日:2005-03-03
标题:Cyclic compound having quinolylalkylthio group
发明人：KAWASHIMA KENJI; HONDA TAKAHIRO; TAJIMA HISASHI; OKAMOTO KAZUYOSHI; YAMAMOTO MINORU
权利人:SANTEN PHARMACEUTICAL CO LTD
摘要:The present invention relates to a synthesis study of novel cyclic compounds having a quinolylalkylthio group represented by the formula (1), and pharmacological actions of the compounds. n nIn the formula, the ring X represents:n n nwhich may have halogen and/or alkyl; R 1 and R 2 independently represent hydrogen, alkyl, cycloalkyl, aryl or a (non) aromatic heterocycle; R 3 represents qinolyl; A represents sulfur, sulfinyl or sulfonyl; and B represents alkylene.

专利号:CN-106588926-A
优先权日:2016-12-28
标 题 :A kind of 2,7-diaza[3,2,1]bicyclooctane and its derivatives and their synthesis method and application

专利号:CN-106588926-B
优先权日:2016-12-28
标题:A kind of 2,7-diaza[3,2,1]bicyclooctane and its derivatives and their synthesis method and application