CAS: 540-61-4; Aminoacetonitrile

该化合物是一种该化合物是一种纯度高的,无色的淡黄色液体,确保合成应用的一贯性能.需要妥善处理,因为其湿度敏感度和潜在毒性.建议在惰性条件下进行储存以保持稳定.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

formaldehyd hydrogen cyanide methyleneaminoacetonitrile chloroacetonitrile5-isopropylidene-imidazolidine-2,4-dithione N,N'-Di-(cyanomethyl)-melamin 1,4-diazaspiro[4,5]decan-2-one H-thiazol-2-one5-(4-chloro-benzylidenamino)-3H-thiazol-2-one

合成工艺路线路线简述

  • 合成目标产物 Aminoacetonitrile 主要起始原料 Glycinamide
  • (文献来源)合成步骤主要原料 Glycinamide
Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于盐酸体系中,化学反应生成 氨基乙腈
参考文献:Jay; Curtius,Chemische Berichte,1894,Vol. 27,P. 60
标题:Jay; Curtius,Chemische Berichte,1894,Vol. 27,P. 60

海关参考信息

专利信息


专利号:US-11008298-B2
优先权日:2019-05-24
标 题:Synthesis of 5-hydroxymethylfurfural
发明人:MOSIER NATHAN SCOTT; OVERTON JONATHAN CHRISTOPHER
权利人:PURDUE RESEARCH FOUNDATION
摘要:The present disclosure relates to a novel and improved synthesis of 5-hydroxymethylfurfural (HMF) from a glucose source. The synthesis of 5-hydroxymethylfurfural (HMF) is carried out by reacting a mixture comprising a Brønsted acid, a Lewis acid, water, dimethyl sulfoxide (DMSO), acetonitrile, and a glucose source.

专利号:US-10364262-B2
优先权日:2012-07-17
标 题 :Method for the synthesis of N-phosphonomethyliminodiacetic acid
发明人:DEVAUX ALBERT; BURCK SEBASTIAN; NOTTE PATRICK
权利人:MONSANTO TECHNOLOGY LLC
摘要:A method for synthesis of N-phosphonoalkyliminodiacetic acid or derivatives thereof by forming a reaction mixture having an acid catalyst, a compound of the following general formula R1—CH2—NX—CH2—R2 and a compound having one or more P—O—P anhydride moieties to form a compound having a formula R1—CH2—N(—CH2PO3R32)(—CH2—R2) wherein in R1—CH2—NX—CH2—R2: X is —CH2—OH or —CH2—COOH; R1 and R2 are independently selected from the group consisting of nitrile, C1-C4 alkyl carboxylate, and carboxylic acid for when X is —CH2—OH, or R1 and R2 are both carbonyl groups linked by a hydrogen substituted nitrogen atom or a C1-C4-alkyl substituted nitrogen atom; and R3 is H, an alkyl group, or an aryl group; the anhydride moieties in the P—O—P anhydride compound have one P atom at the oxidation state (+III) and one P atom at the oxidation state (+III) or (+V); and 2) hydrolyzing the mixture to form N-phosphonomethyliminodiacetic acid or one of its derivatives.

专利号:US-7728135-B2
优先权日:2005-01-06
标 题:Synthesis of CCR5 receptor antagonists
发明人:SHI XIONGWEI; ZHU MAN; LEONG WILLIAM; DAHANUKAR VILAS; ZAVIALOV ILIA A; PROIETTI CECELIA; ZHAO SHANNON; LEE HONG-CHANG; LIU YI; NGUYEN HOA N; WU WENXUE; D SA BOSCO; LIANG FENG; TRAN LOC THANH
权利人:SCHERING CORP
摘要:The present invention is directed to the synthesis of 4-[4-[(R)-[1-[cyclopropylsulfonyl)-4-piperidinyl](3-fluorophenyl)methyl]-3(S)-methyl-1-piperazinyl]-1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-methylpiperidine], and intermediates therefor from readily available starting materials by a novel route.

专利号:US-7737284-B2
优先权日:2001-01-18
标题 :Synthesis of temozolomide and analogs
发明人:KUO SHEN-CHUN; MAS JANET L; HOU DONALD CHEN-TUNG
权利人:SCHERING PLOUGH CORP
摘要:This invention relates to a novel process for the synthesis of Temozolomide, an antitumor compound, and analogs, and to intermediates useful in this novel process.

专利号:EP-0442576-A1
优先权日:1990-02-13
标 题:Synthesis of cis-beta-lactams with the aid of an alkali metal compound
发明人:VAN KOTEN GERARD; VAN DER STEEN FREDERIK HENDRIK; JASTRZEBSKI JOHANN TONNS BARTH; KLEIJN HENK
权利人:UNIV UTRECHT
摘要:A synthesis of cis -β-lactams in a nearly quantitative yield by a condensation reaction of an alkali metal enolate, a substituted glycine ester and an alkali metal base, with an activated imine, is provided.

专利号:US-6818773-B2
优先权日:2001-10-15
标题:Synthesis of 4-[(Z)-4-bromophenyl)(ethoxyimino) methyl]-1'-[(2,4-dimethyl-1-oxido-3-pyridinyl)carbony)]-4'-methyl-1,4-′bipiperidine
发明人:CHEN MINZHANG; D SA BOSCO ANTHONY; LEONG WILLIAM W; GAN TONG; WONG GEORGE S K; TANG SUHAN; NIELSEN CHRISTOPHER MICHAEL
权利人:SCHERING CORP
摘要:In one embodiment, the present invention describes the synthesis of 4-[(Z)-(4-bromophenyl)(ethoxyimino)methyl]-1'-[(2,4-dimethyl-1-oxido-3-pyridinyl)carbonyl]-4'-methyl-1,4'-bipiperidine, and intermediates therefor from easily available starting materials by a simple route.
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合成参考文献


参考文献:10.1016/j.vetpar.2010.01.012
摘要:Stein PA, Rolfe PF, Hosking BC. The control of inhibited fourth-stage larvae of Haemonchus contortus and Teladorsagia spp. in sheep in Australia with monepantel. Vet Parasitol. 2010 May 11;169(3-4):358–61. doi: 10.1016/j.vetpar.2010.01.012.
参考文献:10.3724/sp.j.1123.2011.00342
摘要:Zhang L, Zhang L, Zhang J, Liu C, Cai C. [Determination of global DNA methylation in tissues by hydrophilic interaction liquid chromatography]. Se Pu. 2011 Apr;29(4):342–5. doi: 10.3724/sp.j.1123.2011.00342.
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