CAS: 84194-36-5; 2-Chloro-4-Fluorobenzaldehyde

• 英文名称2-Chloro-4-Fluorobenzaldehyde
• 中文名称2-氯-4-氟苯甲醛
• IUPAC名称2-chloro-4-fluorobenzaldehyde
• 其它别名2-Chloro-4-fluorobenzaldehyde
• CAS编号84194-36-5
• MFCD编号:MFCD00042527
• EINECS号:617-548-7
• 分子式:C7H4ClFO
• 分子量:158.56
• 产品CID: 1830218
• 产品分类有机原料 → 有机氟化合物 → 氟苯甲醛系列

• 相似结构搜索
• InChIKey: KMQWNQKESAHDKD-UHFFFAOYSA-N
• InChI=1S/C7H4ClFO/c8-7-3-6(9)2-1-5(7)4-10/h1-4H…
• 计算化学: 氢键受体数2.0氢键供体数0.0可旋转键数1.0

物理性质

• 熔点60-63  °C(文献)
• 沸点204.5±0.0 °C at 760 mmHg
• 闪点80.9±21.8 °C
• 密度1.4±0.1 g/cm3
• PSA:17.07
• LogP:1.76
• 折射率1.560
• 蒸汽压0.3±0.4 mmHg at 25°C
• 敏感性空气敏感
• 外观形态白色至几乎白色粉末至晶体
• 储存条件置于阴暗处,密封, 常温干燥保存
• 产品应用医药,农药,液晶材料的中间体.
• 性质描述白色至微黄色液体.沸点118°C-120°C(50毫米汞柱),熔点60°C-63°C.

MSDS等安全信息

• GHS象形图
• GHS符号GHS07;
  注释: Exclamation mark
• 危险类别皮肤腐蚀/刺激 类别2
  严重眼刺激 类别2
  特定目标器官毒性 - 单次接触 类别3
  严重眼刺激 类别2A
• 警示词Warning(警告)
• 危险描述H315 |造成皮肤刺激.
  H319 |造成严重眼刺激.
  H335 |可能引起呼吸道刺激.
• 防范说明P261-P264-P271-P280-P302+P352-P305+P351+P338
• 危险等级IRRITANT
• UN编号NONH for all modes of transport
• 危险品标志Xi
• 安全声明26-37/39-36
• 危险类别码36/37/38
• WGK Germany3

欧盟法规

上下游产品

合成工艺路线路线简述

• 合成目标产物 2-Chloro-4-Fluorobenzaldehyde 主要起始原料 4-Fluorobenzaldehyde
• 112135-96-3 = 84194-36-5
  反应条件:1.1 Catalysts: Formic Acid
  标题:Preparation Of Aryltriazolinones As Herbicides
  参考文献:South Africa]
  
  2761761-94-6 = 84194-36-5 + 1603-40-3
  反应条件:1.1 Catalysts: Cupric Acetate Solvents: 1,2-Dichloroethane; 6 H,Rt
  标题:From Amides To Urea Derivatives Or Carbamates With Chemospecific C-C Bond Cleavage At Room Temperature
  作者:Lv,Cong; Liu,Dan; Muschin,Tegshi; Bai,Chaolumen; Bao,Agula; Et Al
  参考文献:Organic Chemistry Frontiers 日期:2022 卷标:9(5) 页码:1354-1363]
  
  208186-84-9 = 84194-36-5
  反应条件:1.1 Reagents: Oxygen Catalysts: Biphenyl,Sodium Bicarbonate,Tetrabutylammonium Chloride,Tempo,Iridium(1+),[4,4′-Bis(1,1-Dimethylethyl)-2,2′-Bipyridine-Kn1,Kn1′]Bis[2-(2-Pyri... Solvents: Dichloromethane,Water; 24 H,Rt
  标题:Tempo-Mediated Oxidation Of Primary Alcohols To Aldehydes Under Visible Light And Air
  作者:Liu,Dongwang; Zhou,Hongxia; Gu,Xiangyong; Shen,Xiaoqin; Li,Pixu
  参考文献:Chinese Journal Of Chemistry 日期:2014 卷标:32(2) 页码:117-122]
  
  167758-87-4 = 84194-36-5
  反应条件:1.1 Reagents: Aluminate(1-),Hydro(2-Methyl-2-Propanolato)Bis(2-Methylpropyl)-,Lithium (1:1),... Solvents: Toluene; 0 °C
  标题:Application Of Flow Chemistry To The Selective Reduction Of Esters To Aldehydes
  作者:Munoz,Juan De M.; Alcazar,Jesus; De La Hoz,Antonio; Diaz-Ortiz,Angel
  参考文献:European Journal Of Organic Chemistry 日期:2012 卷标:2012(2) 页码:260-263]
  
  110407-59-5 = 84194-36-5
  反应条件:1.1 Reagents: Samarium Catalysts: Cuprous Iodide Solvents: Dimethylformamide; 4 H,25 °C1.2 Reagents: Hydrochloric Acid Solvents: Water; 25 °C
  标题:Samarium-Based Grignard-Type Addition Of Organohalides To Carbonyl Compounds Under Catalysis Of Cui
  作者:Xiao,Shuhuan; Liu,Chen; Song,Bin; Wang,Liang; Qi,Yan; Et Al
  参考文献:Chemical Communications (Cambridge 日期:2021 卷标:57(50) 页码:6169-6172]
  
  101335-11-9 = 84194-36-5
  反应条件:1.1 Reagents: 1,1′-Carbonyldiimidazole Solvents: Dimethylformamide; 2 H,Rt1.2 Reagents: Triethylamine Catalysts: Tris(Dibenzylideneacetone)Dipalladium; 6 H,70 °C
  标题:Use Of Carbonyldiimidazole As An Activator Of Formic Acid In A Tris(Dibenzylideneacetone)Dipalladium-Catalyzed Formylation Of Aryl Iodides
  作者:Nadhagopal,Sundar; Dolas,Zulelal; Silamkoti,Arundutt; Gupta,Anuradha; Mathur,Arvind; Et Al
  参考文献:Synlett 日期:2023 卷标:34(15) 页码:1809-1813]
  
  208186-84-9 = 84194-36-5
  反应条件:1.1 Reagents: Trichloroacetonitrile Catalysts: 1,8-Diazabicyclo[5.4.0]Undec-7-Ene Solvents: Dichloromethane; 30 Min,Rt1.2 Reagents: Dimethyl Sulfoxide; 10 Min,140 °C
  标题:Metal-Free Oxidation Of Trichloroacetimidates To Aldehydes
  作者:Lou,Ji-Cong; Li,Jian-Ye; Sun,Wen-Wu; Wu,Bin
  参考文献:Asian Journal Of Organic Chemistry 日期:2019 卷标:8(2) 页码:265-268]
  
  452-73-3 = 84194-36-5
  反应条件:1.1 Reagents: Bromine,Water Solvents: Water
  标题:Tetrahydrophthalimides
  参考文献:Japan]
  
  874-42-0 = 84194-36-5 + 61072-56-8 + 1550-35-2
  反应条件:1.1 Reagents: Potassium Fluoride,Calcium Fluoride Solvents: Sulfolane
  标题:"Halex" [potassium Fluoride] Fluorination Of Chlorinated Benzaldehydes And Benzoyl Chlorides
  作者:Banks,R. Eric; Mothersdale,Kevin N.; Tipping,Anthony E.; Tsiliopoulos,Efthimios; Cozens,Barry J.; Et Al
  参考文献:Journal Of Fluorine Chemistry 日期:1990 卷标:46(3) 页码:529-37

海关参考信息

• 2903919090-氯苯
  2912110000-甲醛
  2912210000-苯甲醛
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

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