CAS: 588-63-6; (3-Bromopropoxy)Benzene

上下游产品

CAS号109-64-8 1,3-二溴丙烷 | CAS号108-95-2 苯酚 | CAS号6180-61-6 丙二醇苯醚 | CAS号66003-76-7 二苯基三氟甲磺酸碘 | CAS号627-18-9 3-溴-1-丙醇 | CAS号109-70-6 1-溴-3-氯丙烷 | CAS号27983-04-6 1-(3-溴丙氧基)-4-氯苯 | CAS号3229-70-7 phenoxy radical | CAS号7497-87-2 1-溴-4-(3-溴丙氧基)苯 | CAS号139-02-6 苯酚钠 | CAS号41298-49-1 1-(3-苯氧基丙基)哌嗪 | CAS号1746-13-0 烯丙基苯基醚 | CAS号622-85-5 丙氧基苯 | CAS号21278-62-6 Benzenesulfonyl... | CAS号21278-57-9 2-chloro-4-nitr... | CAS号20904-57-8 N,N-dimethyl-3-... | CAS号122-97-4 3-苯丙醇 | CAS号187737-37-7 propene | CAS号75-19-4 环丙烷 | CAS号108-95-2 苯酚

烯丙基苯基醚置于硫酸,Sodium Bromide,过氧化苯甲酰体系中,用 四氯化碳 作为反应溶剂,化学反应 1.0H,以95%的收率获得产物3-苯氧基溴丙烷
参考文献:一种3-苯氧基溴丙烷或其类似物的制备方法
标题:一种3-苯氧基溴丙烷或其类似物的制备方法
摘要:本发明公开了一种3‑苯氧基溴丙烷或其类似物的制备方法,以廉价且易得的苯酚或其芳香酚和烯丙基化合物,经过取代反应和加成反应得到3‑苯氧基溴丙烷及其类似物产品,为避免使用气态溴化氢的不便,本发明采用溴化盐和酸原位反应生成高浓度氢溴酸以实现第二步加成反应,工艺操作简单,条件易控制,原子经济性好,从环境影响方面是低污染,零排放的符合当前绿色化学合成方向,从成本经济方面是由于烯烃的直接利用在很大程度上降低了成本.

专利信息

专利号:US-8975427-B2
优先权日:2010-04-28
标题 :Synthesis of alkyl cyclopentadiene compounds
发明人：HARLAN C JEFF; CAO XIANYI; RIX FRANCIS C
权利人:HARLAN C JEFF; CAO XIANYI; RIX FRANCIS C; UNIVATION TECH LLC
摘要:A method of synthesizing an alkyl cyclopentadiene compound is disclosed. The method includes contacting at least one cyclopentadienyl anion source and at least one alkyl group source to form at least one alkyl cyclopentadiene compound. The method further includes extracting the alkyl cyclopentadiene compound with a hydrocarbon solvent. The alkyl cyclopentadiene compound may be converted to a metallocene catalyst compound.

专利号:US-6774125-B2
优先权日:1998-06-22
标 题:Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：AUDIA JAMES E; THOMPSON RICHARD C; WILKIE STEPHEN C; BRITTON THOMAS C; PORTER WARREN J; HUFFMAN GEORGE W; LATIMER LEE H
权利人:ELAN PHARM INC; LILLY CO ELI
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-6509331-B1
优先权日:1998-06-22
标题:Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：AUDIA JAMES E; THOMPSON RICHARD C; WILKIE STEPHEN C; BRITTON THOMAS C; PORTER WARREN J; HUFFMAN GEORGE W; LATIMER LEE H
权利人:ELAN PHARM INC; LILLY CO ELI
摘要:Disclosed are compounds which inhibit beta-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits beta-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-7390801-B2
优先权日:1996-12-23
标题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THORSETT EUGENE D; PLEISS MICHAEL A; LATIMER LEE H; JOHN VARGHESE; FREEDMAN STEPHEN; BRITTON THOMAS C; AUDIA JAMES A; REEL JON K; DRESSMAN BRUCE A; DROSTE JAMES J; HENRY STEVEN S; STUCKY RUSSELL D; PORTER WARREN J
权利人:ATHENA NEUROSCIENCES INC; LILLY CO ELI
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-11274079-B2
优先权日:2018-04-12
标题:2-(2,2-diarylethyl)-cyclic amine derivative or salt, synthesis method, application and composition thereof
发明人：LIANG XINMIAO; ZHAO YAOPENG; LIU YANFANG; WANG JIXIA; WANG CHANGJIAN; WANG ZHIWEI; DU NANA; ZHANG XIULI; GUO ZHIMOU; WANG CHAORAN
权利人:DALIAN INST CHEM & PHYSICS CAS
摘要:The disclosure relates to a 2-(2,2-diarylethyl)-cyclic amine derivative or salt, a synthesis method, an application and a composition thereof. Biological activity test shows that this kind of 2-(2,2-diarylethyl)-cyclic amine derivative has good M-receptor antagonistic activity; and can be used as an active component of drugs for the treatment of the diseases mediated or regulated by muscarinic receptors, such as asthma, chronic obstructive pulmonary disease (COPD), overactive bladder (OAB), bronchospasm with chronic obstructive pulmonary disease, visceral spasm, irritable bowel syndrome, Parkinson's disease, depression or anxiety, schizophrenia and related mental diseases.

专利号:WO-2018150437-A1
优先权日:2017-02-14
标题 :A process for preparing aclidinium bromide and intermediates thereof
发明人：REDDY G NITHUN; REDDY G SAMHITHA; REDDY G MADAALASA; RAMANI M; REDDY G PRATAP
权利人:GBR LABORATORIES PVT LTD; RACHANA PHARMA TECH
摘要:Provided herein is a process for synthesis of aclidinium bromide and intermediates thereof, wherein the process for the preparation of aclidinium bromide increases the % yield of aclidinium bromide by about 70% to 90%.