CAS: 168833-80-5; 3-(3-(Trifluoromethoxy)Phenyl)Acrylic Acid

该化合物是一种有机化合物,其独特的结构特征包括一个含有三氟甲基苯氧基的三氟甲基苯氧基的肉酸脊柱,与芳香环相连,该化合物通常具有芳香和盒状酸功能的特性,如潜在的酸性和各种化学反应中的再活性;三氟氧基的出现会增加其亲脂性,并可能影响其生物活动,使其对医药化学和材料科学感兴趣;该化合物在室温下很固,可能具有中度溶解性;其氟化性质可产生独特的电子特性,有可能影响其与生物目标或材料的相互作用;此外,3-(三氟氧基苯氧基)丙酸可能会表现出紫外体吸收特性,使其在光化应用中有用;与许多氟化化合物一样,它也可能对环境持久性和毒性产生影响,需要在研究和工业环境中仔细处理和评估.

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175675-63-5 783-13-1 199679-35-1

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ECHA物质C&L通报

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CAS号168833-77-0 3-(三氟甲氧基)-苯丙酸

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    专利信息


    专利号:US-6531470-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-6562844-B2
    优先权日:1998-01-23
    标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-7002020-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.
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    参考DOI号:10.1039/c9cc04795f
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