专利号:US-7026511-B2 优先权日:2002-08-30 标 题 :Synthesis of N-vinylformamide 发明人:BECKMAN ERIC J; CHAPMAN TOBY M; FAVERO CEDRICK; CAPELLI CHRISTOPHER C; SWIFT HAROLD E; CARROLL WILLIAM EAMON 权利人:SNF SA 摘要:A process to produce N-vinylformamide includes the steps of: reacting hydroxyethyl formamide with a reactant comprising at least one cyclic anhydride group to form an ester, and dissociating the ester via heat in a thin film evaporation to synthesize N-vinylformamide and a compound comprising at least one diacid group, the N-vinylformamide separating from the diacid during the thin film evaporation. The reactant including at least one cyclic anhydride group can, for example, be succinic anhydride, maleic anhydride, phthalic anhydride, (2-docecen-1-yl)succinic anhydride, exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride or a polymer including at least one cyclic anhydride group. A process to produce N-vinylformamide comprises the steps of: mixing acetaldehyde, formamide and a source of anhydride in a single reaction vessel, reacting the acetaldehyde, formamide and the source of anhydride in the reaction vessel under pressure, dissociating an ester formed by a reaction between the source of anhydride and hydroxyethyl formamide formed in the reaction vessel to synthesize N-vinylformamide and a compound comprising at least one diacid group.
专利号:US-2005033089-A1 优先权日:2002-08-30 标题 :Synthesis of N-vinyl formamide
专利号:US-4379928-A 优先权日:1981-03-04 标 题 :Synthesis of amides 发明人:THEODOROPULOS SPYROS 权利人:UNION CARBIDE CORP 摘要:Alkyl amides have been synthesized from cyclic anhydrides, carboxyl acids and their esters by contacting them with an amine carbamic acid salt.
专利号:EP-0062161-B1 优先权日:1981-03-04 标 题:Synthesis of amides using carbamic-acid salts
专利号:WO-2005087712-A1 优先权日:2004-02-27 标题 :Synthesis of n-vinyl formamide
专利号:EP-0062161-A1 优先权日:1981-03-04 标 题 :Synthesis of amides using carbamic-acid salts
[参考文献]: Vinod Vellora Thekkae Padil, Et Al. Dodecenylsuccinic Anhydride Derivatives Of Gum Karaya (Sterculia Urens): Preparation, Characterization, And Their Antibacterial Properties. J Agric Food Chem. 2015 Apr 15;63(14):3757-65. [参考文献]: Y Nakamura, Et Al. A Quantitative Comparison Of Induction And Challenge Concentrations Inducing A 50% Positive Response In Three Skin Sensitization Tests; The Guinea Pig Maximization Test, Adjuvant And Patch Test And Buehler Test. J Toxicol Sci. 1999 May;24(2):123-31.
合成参考文献
摘要:National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.