CAS: 69555-14-2; Ethyl 2-((Diphenylmethylene)Amino)Acetate

上下游产品

diazoacetic acid ethyl ester Benzophenone imine glycine ethyl ester hydr°Chloride ethyl 2-acetoxy-2-diphenylmethyleneaminoacetate2,2-Diphenyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-dihydro-oxazole-4-carboxylic acid ethyl ester 2-amino-hexanoic acid ethyl N-(diphenylmethylene)-4-(bromomethyl)-D,L-phenylalaninate 2-(Benzhydrylidene-amino)-butyric acid ethyl ester

苯基氯化镁 以 四氢呋喃,二氯甲烷 作为反应溶剂,化学反应生成 二苯亚甲基甘氨酸乙酯
参考文献: Pteridinones As Inhibitors Of Polo-Like Kinase[fr] Ptéridinones En Tant Qu'Inhibiteurs De Polo-Like Kinase
标题: Pteridinones As Inhibitors Of Polo-Like Kinase[fr] Ptéridinones En Tant Qu'Inhibiteurs De Polo-Like Kinase
摘要:本发明提供了具有如下结构式(I)的化合物或其盐或溶剂化物,其中环a,X,R1,R2,R3,R4,R5和r6的定义如本文所述.本发明还提供了包括本发明化合物的药物组合物以及制造和使用本发明化合物和组合物的方法,例如,在治疗和预防各种疾病,如帕金森病.

专利信息

专利号:US-2015080598-A1
优先权日:2012-03-30
标题:Asymmetric synthesis for preparing fluoroleucine alkyl esters
发明人：HUMPHREY GUY; CHUNG CHEOL; RIVERA NELO; BELYK KEVIN
权利人:MERCK SHARP & DOHME
摘要:The instant invention describes a novel asymmetric synthesis of fluoroleucine alkyl esters which utilizes a phase transfer catalyst and a solid additive.

专利号:US-8324417-B2
优先权日:2009-08-19
标题:Process for the preparation of (S)-2-amino-5-cyclopropyl-4,4-difluoropentanoic acid and alkyl esters and acid salts thereof
发明人：HART BARRY; DENER JEFF; GREEN MICHAEL; STANDEN MICHAEL; KOCIAN OLDRICH
权利人:HART BARRY; DENER JEFF; GREEN MICHAEL; STANDEN MICHAEL; KOCIAN OLDRICH; VIROBAY INC
摘要:The present invention relates to a process for the preparation of alkyl esters of (S)-2-amino-5-cyclopropyl-4,4-difluoropentanoic acid, which are intermediates useful in the synthesis of (S)—N-(1-cyanocyclopropyl)-5-cyclopropyl-4,4-difluoro-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)pentanamide and related compounds, which are compounds that are cysteine protease inhibitors.

专利号:US-2021395200-A1
优先权日:2018-11-16
标 题:Synthetic processes for the production of 1-((3s,4r)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl)-3-phenylurea
发明人：ORTIZ ADRIAN; BOROVIKA ALINA; KOLOTUCHIN SERGEI; LUZUNG MICHAEL R; NYE JEFFREY A; TAN YICHEN; ZARETSKY SERGE; ZHU JASON J; EASTGATE MARTIN D
权利人:BRISTOL MYERS SQUIBB CO
摘要:Highly efficient processes are provided for preparing key intermediates in the synthesis of compounds (I). The process are broadly applicable and can provide selected components having a variety of substituents. Some intermediates are claimed.

专利号:US-6245919-B1
优先权日:1996-06-28
标 题:Cyclopropylglycine derivatives and agonists for metabotronic L-glutamate receptors
发明人：SHINOZAKI HARUHIKO; TAGUCHI TAKEO; ISHIDA MICHIKO
权利人:SHINOZAKI HARUHIKO; TAGUSHI TAKEO; NIPPON CHEMIPHAR CO
摘要:A cyclopropylglycine derivative having the following formula:and an intermediate compound for the synthesis of the cyclopropylglycine derivative are novel compounds. The cyclopropylglycine derivative shows a selectivity higher than that of the known agonists to metabotropic L-glutamate receptors, and therefore is a metabotropic type agonist to L-glutamate which has excellent characteristics.

专利号:WO-2009085858-A1
优先权日:2007-12-21
标题 :Process for the synthesis of 3-amino-3-cyclobutylmethyl-2-hydroxypropionamide or salts thereof

专利号:WO-2008138621-A2
优先权日:2007-05-16
标题:Synthesis of aminocyclopentane carboxylic acids