专利号:US-11583842-B2 优先权日:2019-07-24 标题 :Zwitterionic catalysts for (trans)esterification: application in fluoroindole-derivatives and biodiesel synthesis 发明人:YEUNG YING-YEUNG; LAM YING-PONG; KE ZHIHAI; WANG XINYAN; TAN FEI; NG WING-HIN; TSE YING-LUNG STEVE 权利人:UNIV HONG KONG CHINESE 摘要:An amide/iminium zwitterion catalyst has a catalyst pocket size that promotes transesterification and dehydrative esterification. The amide/iminium zwitterions are easily prepared by reacting aziridines with aminopyridines. The reaction can be applied a wide variety of esterification processes including the large-scale synthesis of biodiesel. The amide/iminium zwitterions allow the avoidance of strongly basic or acidic condition and avoidance of metal contamination in the products. Reactions are carried out at ambient or only modestly elevated temperatures. The amide/iminium zwitterion catalyst is easily recycled and reactions proceed in high to quantitative yields.
专利号:WO-9630393-A1 优先权日:1995-03-27 标 题:A method for the synthesis of mixtures of compounds 发明人:BECKER KATHERINE; DEWITT SHEILA HOBBS 权利人:WARNER LAMBERT CO 摘要:Described is a method of synthesizing a plurality of compounds in a plurality of wells comprising the steps of: (a) providing a plurality of test wells in a plurality of arrays of the wells; (b) reacting in at least a one step reaction a first reagent with a plurality of reagents called building blocks in the test well to obtain a unique product designed to be the same in each array; and (c) continuing to react reagents such that there are multiple reagents resulting in mixtures of multiple different products in each well.
专利号:US-5663432-A 优先权日:1995-05-18 标 题:Process for the preparation of 5-amino-2,4,6-Triiodoisophthalic acid dichloride by chlorination with thionyl chloride in the presence of a catalyst 发明人:VILLA MARCO; POZZOLI CLAUDIO; RUSSO LAURA; CASTALDI GRAZIANO 权利人:ZAMBON SPA 摘要:A process for the preparation of 5-amino-2,4,6-triiodoisophthalic acid dichloride by chlorination of 5-amino-2,4,6-triiodoisophthalic acid with thionyl chloride in the presence of a suitable solvent characterized in that the reaction is carried out in the presence of catalytic amounts of a tetraalkylammonium salt of formula R1R2R3R4NX (I) wherein X is halogen, mesylate or tosylate; R1, R2, R3 and R4, the same or different, are C1-C20 alkyl groups so that the total number of carbon atoms of the groups R1, R2, R3 and R4 is higher than 16. The 5-amino-2,4,6-triiodoisophthalic acid dichloride obtained according to the process of the present invention is useful as intermediate in the synthesis of iodinated contrast media.
专利号:IT-MI951004-A1 优先权日:1995-05-18 标 题:PROCESS FOR THE PREPARATION OF A USEFUL INTERMEDIATE IN THE SYNTHESIS OF ORGANIC COMPOUNDS
参考标题:Zwitterionic Catalysts For (Trans)Esterification: Application In Fluoroindole-Derivatives And Biodiesel Synthesis 摘要:An Amide/iminium Zwitterion Catalyst Has A Catalyst Pocket Size That Promotes Transesterification And Dehydrative Esterification. The Amide/iminium Zwitterions Are Easily Prepared By Reacting Aziridines With Aminopyridines. The Reaction Can Be Applied A Wide Variety Of Esterification Processes Including The Large-Scale Synthesis Of Biodiesel. The Amide/iminium Zwitterions Allow The Avoidance Of Strongly Basic Or Acidic Condition And Avoidance Of Metal Contamination In The Products. Reactions Are Carried Out At Ambient Or Only Modestly Elevated Temperatures. The Amide/iminium Zwitterion Catalyst Is Easily Recycled And Reactions Proceed In High To Quantitative Yields.
合成参考文献
参考文献:10.1007/s00216-006-0530-2 摘要:Cortina M, Duran A, Alegret S, del Valle M. A sequential injection electronic tongue employing the transient response from potentiometric sensors for anion multidetermination. Analytical and Bioanalytical Chemistry. 2006 Jun 24;385(7):1186–94. doi: 10.1007/s00216-006-0530-2. 参考文献:10.2116/analsci.33.159 摘要:Yamamoto K, Mitsuda S, Ohtake N, Murashige N, Ohmuro S, Yuchi A. Perchlorate Selectivity of Anion Exchange Resins as Evaluated Using Ion-Selective Electrodes. Analytical Sciences. 2017 Feb 10;33(2):159–63. doi: 10.2116/analsci.33.159.