1,2-二溴-3-硝基苯置于乙醇,氨体系中,化学反应生成 2-溴-6-硝基苯胺 参考文献:Koerner; Contardi,Atti Della Accademia Nazionale Dei Lincei,Classe Di Scienze Fisiche,Matematiche E Naturali,Rendiconti,1906,Vol. <5> 15 I,P. 526 标题:Koerner; Contardi,Atti Della Accademia Nazionale Dei Lincei,Classe Di Scienze Fisiche,Matematiche E Naturali,Rendiconti,1906,Vol. <5> 15 I,P. 526
专利信息
专利号:US-7332505-B2 优先权日:1999-02-26 标 题 :Nitrosated and nitrosylated proton pump inhibitors, compositions and methods of use 发明人:GARVEY DAVID S; LETTS L GORDON; RICHARDSON STEWART K; TAM SANG WILLIAM; WANG TIANSHENG 权利人:NITROMED INC 摘要:The present invention describes novel nitrosated and/or nitrosylated proton pump inhibitor compounds, and novel compositions comprising at least one proton pump inhibitor compound that is optionally substituted with at least one NO and/or NO 2 group, and, optionally, at least one compound that donates, transfers, or releases nitric oxide, induces the production of endogenous nitric oxide or endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase, and/or at least one nonsteroidal antiinflammatory drug, selective COX-2 inhibitor, antacid, bismuth-containing reagent, acid-degradable antibacterial compound, and mixtures thereof. The present invention also provides methods for treating and/or preventing gastrointestinal disorders; facilitating ulcer healing; decreasing the recurrence of ulcers; improving gastroprotective properties, anti- Helicobacter pylon properties or antacid properties of proton pump inhibitors; decreasing or reducing the gastrointestinal toxicity associated with the use of nonsteroidal antiinflammatory compounds; treating Helicobacter pylori and viral infections. The compounds and/or compositions of the present invention can also be provided in the form of a pharmaceutical kit.
专利号:RU-2186055-C2 优先权日:1995-05-24 标 题 :Method of synthesis of derivatives 3-carboxy-4-hydroxybenzaldehyde, method of synthesis of 4-hydroxybenzaldehyde, methods of synthesis of vanillin and ethylvanillin
专利号:US-5639987-A 优先权日:1994-11-29 标题:Compositions modifying ballistic properties and propellants containing such compositions 发明人:BERTELEAU GERARD; FONBLANC GILLES; LONGEVIALLE YVES; RAT MAURICETTE 权利人:POUDRES & EXPLOSIFS STE NALE 摘要:The present invention lies in the field of compositions which modify the ballistic properties of solid propellants and in that of the double-base solid propellants containing these compositions. Various lead compounds are known to be effective in this function, but these compounds are toxic; the problem which is solved by the present invention is to replace these lead compounds with nontoxic compounds which furthermore do not impair other properties and the performance values of the propellants. The modifying compounds are chosen from the group consisting of beta -resorcylates and gamma -resorcylates. The invention also relates to processes for the synthesis of some of these products. Finally, it relates to double-base solid propellants containing these compounds.
专利号:RU-2164911-C2 优先权日:1995-02-20 标 题:Method of synthesis of substituted 4-hydroxybenzaldehyde
专利号:TW-201215582-A 优先权日:2010-10-07 标 题 :The synthesis of single-phase BiFeO3 ceramics and the method to enhance ferroelectric and ferromagnetic properties
专利号:CN-103073598-A 优先权日:2012-10-12 标题 :Synthesis of Mono(Multi)nuclear Complexes of Wallenschiff Base and Bismuth
参考文献:10.1055/s-0031-1289620 摘要:Narender N, Kandepi V. Ecofriendly Oxidative Nuclear Halogenation of Aromatic Compounds Using Potassium and Ammonium Halides. Synthesis. 2011 Nov 24;44(01):15–26. doi: 10.1055/s-0031-1289620. 参考文献:10.1107/s2053229618013608 摘要:Marek PH, Urban M, Madura ID. The study of interactions with a halogen atom: influence of NH2 group insertion on the crystal structures of meta-bromonitrobenzene derivatives. Acta Crystallogr C Struct Chem. 2018 Nov 01;74(Pt 11):1509–17. doi: 10.1107/s2053229618013608.