CAS: 59255-95-7; 2-Bromo-6-Nitroaniline

该化合物是一种有机化合物,其特征是附在苯环上的溴和硝功能组,该化合物的特征是:在芳香环第二位置有溴原子,在芳香环第六位置有硝基组,在各种合成应用中也有氨基(NH2),这些替代组的存在会影响其化学反应和物理特性.典型的情况是,2-溴-6-硝基苯胺等化合物在极地溶剂中表现出中等溶性,而硝基质组可增强电动力替代反应的再活性.溴原子可作为一个遗留组,在各种合成应用中有用.此外,硝基子组可产生重大的电镀特性,影响化合物的总体再活性和稳定性.在处理该化合物时,应注意采取安全防范措施,因为这可能对健康构成典型的卤化和硝基化合物构成典型的健康风险.

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CAS号88-74-4 2-硝基苯胺 | CAS号245115-83-7 N-(2-溴-6-硝基-苯基)-乙酰胺 | CAS号615-36-1 2-溴苯胺 | CAS号26429-41-4 1,2-二溴-3-硝基苯 | CAS号98775-19-0 1-溴-2-甲氧基-3-硝基苯 | CAS号614-76-6 2'-溴乙酰苯胺 | CAS号583-53-9 1,2-二溴苯 | CAS号7664-41-7 氨 | CAS号3970-37-4 1-溴-2-氯-3-硝基苯 | CAS号26429-41-4 1,2-二溴-3-硝基苯 | CAS号83741-35-9 4-溴-1H-苯并咪唑 | CAS号20358-05-8 2-氨基-7-溴苯并噻唑 | CAS号52488-36-5 4-溴吲哚 | CAS号32337-96-5 3-溴-2-碘硝基苯 | CAS号1575-36-6 3-溴-1,2-二氨基苯

合成工艺路线路线简述

    1,2-二溴-3-硝基苯置于乙醇,氨体系中,化学反应生成 2-溴-6-硝基苯胺
    参考文献:Koerner; Contardi,Atti Della Accademia Nazionale Dei Lincei,Classe Di Scienze Fisiche,Matematiche E Naturali,Rendiconti,1906,Vol. <5> 15 I,P. 526
    标题:Koerner; Contardi,Atti Della Accademia Nazionale Dei Lincei,Classe Di Scienze Fisiche,Matematiche E Naturali,Rendiconti,1906,Vol. <5> 15 I,P. 526

    专利信息


    专利号:US-7332505-B2
    优先权日:1999-02-26
    标 题 :Nitrosated and nitrosylated proton pump inhibitors, compositions and methods of use
    发明人:GARVEY DAVID S; LETTS L GORDON; RICHARDSON STEWART K; TAM SANG WILLIAM; WANG TIANSHENG
    权利人:NITROMED INC
    摘要:The present invention describes novel nitrosated and/or nitrosylated proton pump inhibitor compounds, and novel compositions comprising at least one proton pump inhibitor compound that is optionally substituted with at least one NO and/or NO 2 group, and, optionally, at least one compound that donates, transfers, or releases nitric oxide, induces the production of endogenous nitric oxide or endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase, and/or at least one nonsteroidal antiinflammatory drug, selective COX-2 inhibitor, antacid, bismuth-containing reagent, acid-degradable antibacterial compound, and mixtures thereof. The present invention also provides methods for treating and/or preventing gastrointestinal disorders; facilitating ulcer healing; decreasing the recurrence of ulcers; improving gastroprotective properties, anti- Helicobacter pylon properties or antacid properties of proton pump inhibitors; decreasing or reducing the gastrointestinal toxicity associated with the use of nonsteroidal antiinflammatory compounds; treating Helicobacter pylori and viral infections. The compounds and/or compositions of the present invention can also be provided in the form of a pharmaceutical kit.

    专利号:RU-2186055-C2
    优先权日:1995-05-24
    标 题 :Method of synthesis of derivatives 3-carboxy-4-hydroxybenzaldehyde, method of synthesis of 4-hydroxybenzaldehyde, methods of synthesis of vanillin and ethylvanillin

    专利号:US-5639987-A
    优先权日:1994-11-29
    标题:Compositions modifying ballistic properties and propellants containing such compositions
    发明人:BERTELEAU GERARD; FONBLANC GILLES; LONGEVIALLE YVES; RAT MAURICETTE
    权利人:POUDRES & EXPLOSIFS STE NALE
    摘要:The present invention lies in the field of compositions which modify the ballistic properties of solid propellants and in that of the double-base solid propellants containing these compositions. Various lead compounds are known to be effective in this function, but these compounds are toxic; the problem which is solved by the present invention is to replace these lead compounds with nontoxic compounds which furthermore do not impair other properties and the performance values of the propellants. The modifying compounds are chosen from the group consisting of beta -resorcylates and gamma -resorcylates. The invention also relates to processes for the synthesis of some of these products. Finally, it relates to double-base solid propellants containing these compounds.

    专利号:RU-2164911-C2
    优先权日:1995-02-20
    标 题:Method of synthesis of substituted 4-hydroxybenzaldehyde

    专利号:TW-201215582-A
    优先权日:2010-10-07
    标 题 :The synthesis of single-phase BiFeO3 ceramics and the method to enhance ferroelectric and ferromagnetic properties

    专利号:CN-103073598-A
    优先权日:2012-10-12
    标题 :Synthesis of Mono(Multi)nuclear Complexes of Wallenschiff Base and Bismuth
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    合成参考文献


    参考文献:10.1055/s-0031-1289620
    摘要:Narender N, Kandepi V. Ecofriendly Oxidative Nuclear Halogenation of Aromatic Compounds Using Potassium and Ammonium Halides. Synthesis. 2011 Nov 24;44(01):15–26. doi: 10.1055/s-0031-1289620.
    参考文献:10.1107/s2053229618013608
    摘要:Marek PH, Urban M, Madura ID. The study of interactions with a halogen atom: influence of NH2 group insertion on the crystal structures of meta-bromonitrobenzene derivatives. Acta Crystallogr C Struct Chem. 2018 Nov 01;74(Pt 11):1509–17. doi: 10.1107/s2053229618013608.
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