CAS: 135459-87-9; 2,2'-((5-Carboxy-4-(Carboxymethyl)-3-Cyanothiophen-2-yl)Azanediyl)Diacetic Acid, Distrontium Salt

专利信息

专利号:US-7462714-B2
优先权日:2002-09-24
标题 :Process for the industrial synthesis of the methyl diester of 5-amino-3-carboxymethyl-4-cyano-2-thiophenecarboxylic acid, and application to the synthesis of bivalent salts of ranelic acid and their hydrates
发明人：VAYSSE-LUDOT LUCILE; LECOUVE JEAN-PIERRE; LANGLOIS PASCAL
权利人:SERVIER LAB
摘要:Process for the industrial synthesis of the compound of formula (I): n nApplication to the synthesis of bivalent salts of ranelic acid and more especially strontium ranelate and its hydrates.

专利号:US-7091364-B2
优先权日:2002-09-24
标题:Process for the industrial synthesis of tetraesters of 5-[bis(carboxymethyl)amino]-3-carboxymethyl-4-cyano-2-thiophenecarboxylic acid, and application to the synthesis of bivalent salts of ranelic acid and their hydrates
发明人：VAYSSE-LUDOT LUCILE; LECOUVE JEAN-PIERRE; LANGLOIS PASCAL
权利人:SERVIER LAB
摘要:The process for the industrial synthesis of compounds of formula (I): n nwherein R and R′, which are the same or different, each represent linear or branched (C 1 –C 6 )alkyl.n n Application to the synthesis of bivalent salts of ranelic acid and more especially strontium ranelate and its hydrates.

专利号:US-7214805-B2
优先权日:2002-09-24
标题:Process for the industrial synthesis of strontium ranelate and its hydrates
发明人：VAYSSE-LUDOT LUCILE; LECOUVE JEAN-PIERRE; LANGLOIS PASCAL
权利人:SERVIER LAB
摘要:The process for the industrial The synthesis of strontium ranelate of formula (I): n nand its hydrates.

专利号:US-8063100-B2
优先权日:2007-09-26
标 题 :Process for the synthesis of strontium ranelate and its hydrates
发明人：VAYSSE-LUDOT LUCILE; LECOUVE JEAN-PIERRE; LANGLOIS PASCAL
权利人:VAYSSE-LUDOT LUCILE; LECOUVE JEAN-PIERRE; LANGLOIS PASCAL; SERVIER LAB
摘要:A process for the industrial synthesis of strontium ranelate of formula (I): n nand its hydrates.

专利号:US-2012123131-A1
优先权日:2008-08-22
标 题 :Process for the preparation of strontium ranelate
发明人：PRABAHAR KOILPILLAI JOSEPH; KULKARNI PRAVIN BHALCHANDRA; PATIL PRASHANT BHASKARRAO; HIRE KAPIL RAMESH
权利人:PRABAHAR KOILPILLAI JOSEPH; KULKARNI PRAVIN BHALCHANDRA; PATIL PRASHANT BHASKARRAO; HIRE KAPIL RAMESH
摘要:The present invention relates to an improved process for the synthesis of strontium ranelate or hydrates thereof. More particularly, the present invention relates to an effective process for the preparation of a compound of formula III, which is a useful intermediate in the synthesis of strontium ranelate. n n n n n n n n n n wherein R 1 and R 2 represents substituted or unsubstituted linear or branched C 1 -C 6 alkyl group or C 3 -C 12 cyclic group.

专利号:WO-2020225044-A1
优先权日:2019-05-06
标题 :Novel catalyzed synthesis of biodegradable polyesters
发明人：WINDHAB NORBERT; BINDL MARTIN; KARAU ANDREAS; SEIBEL MANUEL; ENDRES THOMAS; SCHUBERT ULRICH SIGMAR; WEBER CHRISTINE; BANDELLI DAMIANO
权利人:EVONIK OPERATIONS GMBH
摘要:The invention relates to a catalytic process for preparing polyester by ring-opening polymerization of at least one substituted glycolide of formula (I) or copolymerization of at least one substituted glycolide of formula (I) with trimethyl carbonate and/or at least one lactone of formula (II), wherein a strontium(II) alkoxide Sr(OR 3 ) 2 , is used as a catalyst.