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CAS号153805-85-7 1-[2-(5-Benzylo... | CAS号1215-59-4 5-苄氧基吲哚 | CAS号1006-94-6 5-甲氧基吲哚 | CAS号153969-91-6 5-(prop-2-ynynl... | CAS号51145-58-5 4-苄氧基苯肼 | CAS号120-72-9 吲哚 | CAS号100-02-7 对硝基苯酚 | CAS号1145-76-2 1-苄氧基-4-硝基苯 | CAS号103404-89-3 5-羟基-DL-色氨酸乙酯盐酸盐 | CAS号3414-19-5 5-羟基吲哚-3-甲醛 | CAS号57477-39-1 3-(1-甲基-4-哌啶基)-... | CAS号31271-90-6 N-(对甲苯磺酰)吲哚 | CAS号394-31-0 5-羟基邻氨基苯甲酸 | CAS号434958-85-7 N-B°C-5-羟基吲哚 | CAS号267875-62-7 ((1H-吲哚-5-基)甲基)... | CAS号882803-11-4 5-羟基-3-(1H)吲唑甲醛 | CAS号699-02-5 2-(4-甲基苯基)乙醇 | CAS号127626-07-7 3-(1,2,3,6-四氢吡啶...合成工艺路线路线简述
- 合成目标产物 5-Hydroxyindole 主要起始原料 5-Methoxyindole
- (文献来源)合成步骤主要原料 5-Methoxyindole
4-苄氧基-1-硝基苯置于10% Palladium On Active Carbon Potassium Tert-Butylate,氢气,溶剂黄146体系中,用 乙醇,N,N-二甲基甲酰胺 用作溶剂,-20.0~25.0 °C,303.98 Kpa 条件下,反应 2.5H,反应生成5-羟基吲哚
参考文献:Makosza,Mieczyslaw; Danikiewicz,Witold; Wojciechowski,Krzysztof,Liebigs Annalen Der Chemie,1988,P. 203-208
标题:Makosza,Mieczyslaw; Danikiewicz,Witold; Wojciechowski,Krzysztof,Liebigs Annalen Der Chemie,1988,P. 203-208
海关参考信息
- 2908199090-其他酚的卤化衍生物
2908999090-其他酚的硝化衍生物
2918290000-其他含酚基羧酸
2905199090-其他饱和一元醇 - 💡 提示:海关信息按照顺序优先匹配,如需确认的海关信息,请参考相关资料。
- 详情请参考:📖 海关编码查询和海关进出口税则
专利信息
专利号:US-4602088-A
优先权日:1984-07-26
标题 :Preparation of enamines from conjugated dienes
发明人:LIN JIANG-JEN
权利人:TEXACO INC
摘要:A method for the preparation of enamines wherein a conjugated diene is reacted with a secondary amine, carbon monoxide and hydrogen (synthesis gas) in solvent solution in the presence of a rhodium catalyst. In accordance with the preferred embodiment, butadiene is reacted with a dialkylamine and synthesis gas in an organic solvent in the presence of a rhodium catalyst to provide the corresponding 1,3-pentadienyl dialkylamine in good yield and with good selectivity. This may be illustrated, for example, by the following equation: H3CCHCHCHCHNR2 + H2O
专利号:US-2003199558-A1
优先权日:2001-12-28
标 题:Hydroxamic acid and its derivatives as inhibitors of melanocyte tyrosinase for topical skin lighteners
发明人:DOOLEY THOMAS P; CHENG LIN
权利人:INTEGRIDERM INC
摘要:Methods, compounds, and formulations are provided to reduce pigmentation in mammalian skin, comprising hydroxamic acid and its derivatives, and especially benzohydroxamic acid and its derivatives. The compounds preferably inhibit pigment synthesis in melanocytes through inhibition of melanocyte tyrosinase. The methods can be used for lightening skin, and for treating uneven skin complexions, which result from hyperpigmentation-related medical conditions such as melasma, age spots, freckles, ochronosis, and lentigo. The compounds can be used medically or cosmetically, and preferably as topical formulations.
专利号:US-12336981-B2
优先权日:2010-09-03
标题 :Compounds and compositions for the inhibition of NAMPT
发明人:BAIR KENNETH W; BAUMEISTER TIMM R; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; DRAGOVICH Peter; GOSSELIN FRANCIS; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; ROTH BRUCE; SMITH CHASE C; WANG ZHONGGUO; YUEN PO-WAI; ZHENG XIAOZHANG
权利人:VALO HEALTH INC; GENENTECH INC
摘要:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:
专利号:US-6140505-A
优先权日:1995-03-10
标 题:Synthesis of benzo fused heterocyclic sulfonyl chlorides
专利号:WO-0053313-A2
优先权日:1999-03-09
标 题:Lanthanide catalysts for synthesis of compounds and combinatorial libraries
专利号:US-7723498-B2
优先权日:2004-06-04
标题:Directed evolution of recombinant monooxygenase nucleic acids and related polypeptides and methods of use
发明人:WOOD THOMAS K; VARDAR GONUL
权利人:UNIV CONNECTICUT
摘要:The present invention relates to novel monooxygenase nucleic acids and polypeptides created using mutagenesis, DNA shuffling, or both, in a single iteration or multiple iterations, and methods for their creation and use. The monooxygenase enzymes of the present disclosure have particular utility as biocatalysts in industrial chemical redox reactions, such as the oxidation of aromatic hydrocarbons, for example, toluene, benzene, or nitrobenzene, into industrially desirable products. The systems and processes of the present invention are especially useful for the coupled synthesis and recovery of catechols, methylcatechols, resorcinols, methylresorcinols, hydroquinones, methylhydroquinones, hydroxybenzenes, cresols, nitrobenzenes, and nitrohydroxyquinones.