CAS: 446-31-1; 4-Amino-2-Fluorobenzoic Acid

上下游产品

CAS号403-24-7 2-氟-4-硝基苯甲酸 | CAS号53312-80-4 2-氟-4-氨基苯腈 | CAS号1427-07-2 2-氟-4-硝基甲苯 | CAS号364-84-1 4-acetamido-2-f... | CAS号452-77-7 3-氟-4-甲基苯胺 | CAS号458-10-6 N-(3-氟-4-甲基苯基)乙酰胺 | CAS号210416-38-9 4-[(4-carboxy-3... | CAS号73792-08-2 4-氨基2-氟苯甲酸甲酯

3-氟-4-甲基苯胺置于盐酸,Potassium Permanganate,Magnesium Sulfate体系中,化学反应生成 4-氨基-2-氟苯甲酸
参考文献:Substituted P-Aminobenzoic Acids
标题:Substituted P-Aminobenzoic Acids
摘要:
DOI:10.1021/ja01238A006

专利信息

专利号:US-2012165520-A1
优先权日:2010-12-23
标题:Process for the synthesis of prodrugs of opioids
发明人：MCGEE PAUL; GARNETT IAN; JUAN E; MANAGE A; CARNIAUX JEAN-FRANCOIS
权利人:MCGEE PAUL; GARNETT IAN; JUAN E; MANAGE A; CARNIAUX JEAN-FRANCOIS
摘要:The present invention provides a process for the synthesis of opioid prodrugs. In particular, the present invention provides a process for the synthesis of opioid prodrugs comprising: treating an opioid, in the form of a salt or a freebase, with a carbonyl synthon to form an activated intermediate and subsequently reacting the activated intermediate with an amine, in the form of a salt or a freebase.

专利号:US-9174943-B2
优先权日:2010-02-24
标 题 :Processes for the synthesis of diarylthiohydantoin and diarylhydantoin compounds
发明人：JAIN RAJENDRA PARASMAL; ANGELAUD REMY; THOMPSON ANDREW; LAMBERSON CAROL; GREENFIELD SCOTT
权利人:JAIN RAJENDRA PARASMAL; ANGELAUD REMY; THOMPSON ANDREW; LAMBERSON CAROL; GREENFIELD SCOTT; MEDIVATION PROSTATE THERAPEUTICS INC
摘要:Processes are provided for the synthesis of diarylthiohydantoin and diarylhydantoin compounds. Medicinal products containing the same find particular use in treating prostate cancer, including castration-resistant prostate cancer and/or hormone-sensitive prostate cancer.

专利号:ES-2671343-T3
优先权日:2010-02-24
标 题 :Processes for the synthesis of diarylthiohydantoin and diarylhydantoin compounds

专利号:JP-2013520519-A
优先权日:2010-02-24
标题:Process for the synthesis of diarylthiohydantoin compounds and diarylhydantoin compounds

专利号:ES-2880354-T3
优先权日:2010-02-24
标 题 :Processes for the synthesis of diarylthiohydantoin and diarylhydantoin compounds

专利号:WO-2011106570-A1
优先权日:2010-02-24
标 题 :Processes for the synthesis of diarylthiohydantoin and diarylhydantoin compounds