CAS: 280-64-8; 9λ2-Borabicyclo[3.3.1]Nonane

上下游产品

CAS号1552-12-1 1,5-环辛二稀 | CAS号21205-91-4 9-硼双环[3,3,1]壬烷,... | CAS号13292-87-0 硼烷二甲硫醚 | CAS号70160-59-7 9-bromo-9-(dime... | CAS号70160-58-6 (1R,5S)-9-chlor... | CAS号14044-65-6 四氢呋喃硼烷络合物 | CAS号149468-33-7 9-(di-tert-buty... | CAS号16940-66-2 硼氢化钠 | CAS号1378876-25-5 | CAS号104828-34-4 methyl 11-(9-bo... | CAS号496-11-7 茚满 | CAS号38050-71-4 8-甲氧基-9-硼杂双环[3.... | CAS号74744-62-0 9,9'-Oxybis(9-b... | CAS号1354969-54-2 [(cyclopentyl)2... | CAS号54844-65-4 (Z)-6-二十一碳烯-11-酮 | CAS号23418-91-9 9-Borabicyclo[3... | CAS号23532-74-3 9-butyl-9-borab... | CAS号318290-86-7 9-pentyl-9-boro...

1,5-Cis,Cis-Cyclooctadiene置于borane N-Ethyl-N-Isopropylaniline Complex体系中,用 1,4-二氧六环 用作溶剂,以87%的收率获得9-硼双环[3.3.1]壬烷
参考文献:分子加成化合物.14.使用新的高反应性n-乙基-N-异丙基嘌呤-硼烷试剂(bach-Ei™)方便地制备代表性的二烷基硼烷试剂
标题:分子加成化合物.14.使用新的高反应性n-乙基-N-异丙基嘌呤-硼烷试剂(bach-Ei™)方便地制备代表性的二烷基硼烷试剂
摘要:使用新的高反应性n-乙基-N-异丙基苯胺-描述了在二恶烷和四氢呋喃中的硼烷试剂(bach-Ei™).
Doi:10.1016/s0040-4020(99)00272-0

专利信息

专利号:US-5849936-A
优先权日:1995-03-15
标题:Method for the synthesis of bis-tetrahydrofuranyl annonaceous acetogenins
发明人：HOYE THOMAS R; TAN LUSHI
权利人:UNIVERISTY OF MINNESOTA
摘要:A method for the synthesis of bis-tetrahydrofranyl Annonaceous acetogenins, including the natural products and analogs thereof, is provided which proceeds by the Pd-mediated coupling of a bis-tetrahydrofuranyl-subunit comprising a terminal alkyne, with a (C4)-hydroxybutenolide subunit comprising a terminal vinyl iodide, followed by selective reduction of the resulting enyne.

专利号:US-11466050-B2
优先权日:2014-09-29
标 题 :Method for peptide synthesis and apparatus for carrying out a method for solid phase synthesis of peptides
发明人：KNAUER SASCHA; ROESE TOBIAS MICHAEL LOUIS; AVRUTINA OLGA; KOLMAR HARALD; UTH CHRISTINA
权利人:SULFOTOOLS GMBH
摘要:The invention relates to a method for peptide synthesis, wherein said method comprises the steps of reacting a first amino acid or a first peptide with an α-amine protected second amino acid in a solvent selected from the group consisting of water, alcohol, and a mixture of water and alcohol, and removing the α-amine protecting group with a deprotecting solution. The invention further relates to protective agents, their use and an apparatus for carrying out a method for solid phase synthesis of peptides.

专利号:US-2019047933-A1
优先权日:2016-03-15
标 题:Process for the synthesis of (2e, 4e, 6z, 8e)-8-(3,4-dihydronaphthalen-1(2h)-ylidene)-3,7-dimethylocta-2, 4, 6-trienoic acid
发明人：ABEL ULRICH; RÉPÃ?SI JÓZSEF; Szabó András; SZÃœCSNÉ CSERÉPI STEFÃ?NIA; Bor Ã?dám
权利人:ABEL ULRICH; REPASI JOZSEF; SZABO ANDRAS; SZUECSNE CSEREPI STEFANIA; BOR ADAM; BRICKELL BIOTECH INC
摘要:This invention relates to a novel method for the synthesis of (2E,4E,6Z,8E)-8-(3,4-dihydronaphthalen-1(2H)-ylidene)-3,7-dimethylocta-2,4,6-trienoic acid. In particular, the invention relates to several improvements in several individual steps of the multi-step synthesis scheme

专利号:US-11479577-B2
优先权日:2016-05-18
标题:Intermediates for the synthesis of bile acid derivatives, in particular of obeticholic acid
发明人：WEYMOUTH-WILSON ALEXANDER; KOMSTA ZOFIA; WALLIS LAURA; EVANS TIMOTHY; DAVIES IEUAN; OTTER CARL; BATCHELOR RHYS
权利人:NZP UK LTD
摘要:The present invention relates to compounds which are intermediates in the synthesis of bile acid derivatives with pharmacological activity. The invention relates to compounds of general formula (I):wherein:, R1, R2, R3, R4, R5, R6 and Y are as defined herein.The compounds are intermediates in the synthesis of synthetic bile acids which are useful in the treatment of conditions such as liver disease. In addition, the invention relates to a method of synthesizing these intermediates and a method of preparing obeticholic acid and obeticholic acid analogues from the compounds of the invention.

专利号:US-8436206-B2
优先权日:2007-08-03
标 题:Process for the synthesis of (7-methoxy-1-naphthyl) acetonitrile and application in the synthesis of agomelatine
发明人：DUBUFFET THIERRY; LECOUVE JEAN-PIERRE; HERMET JEAN-PAUL
权利人:DUBUFFET THIERRY; LECOUVE JEAN-PIERRE; HERMET JEAN-PAUL; SERVIER LAB
摘要:Process for the industrial synthesis of the compound of formula (I) n nApplication of such process in the synthesis of agomelatine.

专利号:US-2004018598-A1
优先权日:2000-05-30
标题 :Bio-intermediates for use in the chemical synthesis of polyketides
发明人：SANTI DANIEL; ASHLEY GARY; MYLES DAVID C
摘要:The present invention relates to compounds made by a subset of modules from one or more polyketide synthase (“PKSâ€?) genes that are used as starting material in the chemical synthesis of novel molecules, particularly naturally occurring polyketides or derivatives thereof. The biologically derived intermediates (“bio-intermediatesâ€?) generally represent particularly difficult compounds to synthesize using traditional chemical approaches due to one or more stereocenters. In one aspect of the invention, an intermediate in the synthesis of epothilone is provided that feeds into the synthetic protocol of Danishefsky and co-workers. In another aspect of the invention, intermediates in the synthesis of discodermolide are provided that feed into the synthetic protocol of Smith and co-workers. By taking advantage of the inherent stereochemical specificity of biological processes, the syntheses of key intermediates and thus the overall syntheses of compounds like epothilone and discodermolide are greaty simplified.