CAS: 40596-44-9; 4-Iodobutyl Acetate

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上下游产品

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1,4-丁二醇二乙酸酯置于吡啶,Ph 6.9 Buffer,对甲苯磺酰氯,Sodium Iodide体系中,化学反应生成 乙酸 4-碘丁酯
参考文献:单保护二醇的非常简单的方法
标题:单保护二醇的非常简单的方法
摘要:已显示来自猪胰腺的脂肪酶(ppl)选择性催化将1,N-二醇双乙酸烷酯水解为相应的单乙酸酯.
DOI:10.1016/0040-4039(95)02273-2

专利信息

专利号:US-4518602-A
优先权日:1982-10-07
标题 :Vinyl carboxylic acid derivatives, their production and use as inhibitors of thromboxane synthetase
发明人：TERAO SHINJI; NISHIKAWA KOHEI
权利人:TAKEDA CHEMICAL INDUSTRIES LTD
摘要:Novel compound of the formula: wherein R1 is a pyridyl group; R2 is a phenyl, thienyl, furyl, naphthyl, benzothienyl or pyridyl group which may have as a substituent a lower alkoxy, a lower alkyl, a halogen, trifluoromethyl, a lower alkenyl or methylenedioxy; R3 is hydrogen, benzyl or a lower alkyl; one of R4 and R5 is hydrogen or a lower alkyl, and the other is an aryloxy, or lower aliphatic hydrocarbon, an alicyclic hydrocarbon having not more than 6 carbon atoms or an aromatic group which may have a substituent, or a group represented by the formula, -S(O)m-R6 (in which R6 is phenyl or a lower alkyl group; m is an integer of 0 to 2), or R4 and R5 each combine with the other to represent one alkylene group; n is an integer of 2 to 6, or a pharmaceutically acceptable salt thereof has a selective inhibitory action on bio-synthesis of thromboxane A2(TXA2) and an effect of enhancing the production of prostaglandin I2(PGI2), and can be used in mammals for to prevention and treatment of arterial thrombosis caused by platelet aggregation or ischemic diseases caused by vasospasms in cardiac, cerebral and peripheral circulatory system (e.g. cardian infarction, apoplexy, infarct of blood vessels in kidney, lung and other organs, pectic ulcer, etc.).