CAS: 16019-31-1; 5-Allyl-4,6-Dichloropyrimidine

相似化合物

16019-33-3 89938-06-7 85826-33-1

上下游产品

CAS号1193-21-1 4,6-二氯嘧啶 | CAS号106-95-6 烯丙基溴 | CAS号16019-30-0 5-烯丙基嘧啶-4,6-二醇 | CAS号2049-80-1 烯丙基丙二酸二乙酯 | CAS号1001397-19-8 4-chloro-7-(2-f... | CAS号14052-82-5 4,6-二氯-5-(2,2-二... | CAS号16019-33-3 4,6-二氯嘧啶-5-乙醛

烯丙基丙二酸二乙酯置于乙醇,Sodium,三氯氧磷体系中,化学反应 27.0H,反应生成5-烯丙基-4,6-二氯嘧啶
参考文献: Cyclolic Hydrazine Derivatives As Hiv Attachment Inhibitors[fr] Dérivés D'Hydrazine Cycliques En Tant Qu'Inhibiteurs De Fixation Du Vih
标题: Cyclolic Hydrazine Derivatives As Hiv Attachment Inhibitors[fr] Dérivés D'Hydrazine Cycliques En Tant Qu'Inhibiteurs De Fixation Du Vih
摘要:提供了公式i的化合物,包括其药用可接受的盐:其中a选自以下组:其中z选自以下组:这些化合物可用作hiv附着抑制剂.

专利信息

专利号:US-9278939-B2
优先权日:2013-09-18
标 题:Methods for preparation of (4,6-dihalo-pyrimidin-5-yl)-acetaldehydes
发明人：LU SHAOPO; LI ZHUOCAI
权利人:SUZHOU JONATHAN NEW MATERIAL TECHNOLOGY CO LTD
摘要:This invention relates to the synthesis of chemical compounds and particularly to methods for the preparation of (4,6-dihalo-pyrimidin-5-yl)-acetaldehydes. The methods involve preparing a compound of the following general formula V from a compound of the following general formula IV through hydrolysis under the action of mercury dichloride and calcium carbonate, according to the following equation: n nwherein X is Cl or Br. The methods offer the benefits of use of highly available materials, high step yields, moderate reaction conditions, simply post-processing and purification, and suitability to industrialized production.