CAS: 487-89-8; Indole-3-Carboxaldehyde

上下游产品

CAS号120-72-9 吲哚 | CAS号700-06-1 3-吲哚甲醇 | CAS号50562-79-3 1-[(4-甲基苯基)磺酰]-... | CAS号87-51-4 吲哚-3-乙酸 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号57476-50-3 3-甲酰基-1H-吲哚-1-甲酸叔丁酯 | CAS号65283-32-1 1H-indol-3-ylme... | CAS号22948-94-3 N-乙酰基吲哚-3-羧甲醛 | CAS号2592-05-4 1H-吲哚-3-甲醛肟 | CAS号51597-80-9 N-((1H-indol-3-... | CAS号105949-28-8 N,N-diethyl-3-(... | CAS号105850-59-7 N-(indol-3-ylid... | CAS号112251-27-1 2-(1H-indol-3-y... | CAS号108583-08-0 4-[[(Z)-indol-3... | CAS号105748-60-5 Methoxybrassinin | CAS号108583-16-0 4-(indol-3-ylid... | CAS号58494-59-0 1-乙基-1H-吲哚-3-甲醛 | CAS号39974-94-2 5-甲氧基-1-甲基吲哚-3-甲醛 | CAS号57476-50-3 3-甲酰基-1H-吲哚-1-甲酸叔丁酯

3-甲基吲哚置于2,3-二氯-5,6-二氰基-1,4-苯醌体系中,用 四氢呋喃,水 作为反应溶剂,以68 %的收率获得产物3-吲哚甲醛
参考文献:铁催化分子内 C-H 胺化合成 N-H 咔唑和吲哚
标题:铁催化分子内 C-H 胺化合成 N-H 咔唑和吲哚
摘要:由第一排过渡金属催化的有氧氧化 C-H/n-H 交叉偶联的发展具有吸引力但具有挑战性.在这里,报道了第一个铁催化的分子内交叉脱氢偶联,用于使用空气作为氧化剂合成咔唑和吲哚.通用且高效的协议允许在绿色条件下形成 C-N 键,具有出色的官能团相容性,以非常好的收率提供范围广泛的 N-H 咔唑和吲哚.令人印象深刻的是,所有咔唑都是由 2-环己烯基氨基芳烃通过c-H 胺化和芳构化过程失去 6H 制备的.此外,它还适用于 C-o 键的形成.
DOI:10.1039/d3Gc00518F

专利信息

专利号:WO-9312076-A1
优先权日:1991-12-13
标题:Reagents for automated synthesis of peptide analogs
发明人：WEBB THOMAS ROY
权利人:CORVAS INT INC
摘要:Reagents suitable for synthesis of peptide analogs using automated peptide synthesis and procedures for synthesis of peptide analogs are provided.

专利号:US-2016031800-A1
优先权日:2013-03-14
标 题:Synthesis of chiral kynurenine compounds and intermediates
发明人：TRETYAKOV ALEXANDER; DROUET KEITH E; SANDERS WILLIAM
权利人:VISTAGEN THERAPEUTICS INC
摘要:Provided are methods for the synthesis of compounds including chiral kynurenine compounds, intermediates useful for the synthesis thereof, and related compounds. For example, methods are provided for the synthesis of L-4-chlorokynurenine.

专利号:US-5283293-A
优先权日:1990-12-14
标 题:Reagents for automated synthesis of peptide analogs
发明人：WEBB THOMAS R
权利人:CORVAS INC
摘要:Reagents suitable for synthesis of peptide analogs using automated peptide synthesis and procedures for synthesis of peptide analogs are provided.

专利号:US-7714063-B2
优先权日:2007-11-15
标 题 :Solid support for Fmoc-solid phase synthesis of peptides
发明人：SRIVASTAVA KRIPA SHANKER; DAVIS MATTHEW RYAN
权利人:MALLINCKRODT INC
摘要:The present invention provides compositions and processes for the solid phase synthesis of polypeptides. In particular, the present invention provides solid supports and processes for preparing solid supports for the synthesis of polypeptides.

专利号:US-11427530-B2
优先权日:2018-02-09
标 题 :Synthesis of 4-chlorokynurenines and intermediates
发明人：LEVIN DANIEL; LEEMING PETER; EISENREICH EMERICH; LIU XUEJUN KARL
权利人:VISTAGEN THERAPEUTICS INC
摘要:The invention relates to an overall enantio-specific synthesis of 4-chlorokynurenine compounds, in particular L-4-chlorokynurenine, with improved yields. Large-scale syntheses are disclosed. The invention also relates to novel intermediates in the synthesis of L-4-chlorokynurenine.

专利号:US-5367072-A
优先权日:1990-12-14
标 题 :Reagents for automated synthesis of peptide analogs
发明人：WEBB THOMAS R
权利人:CORVAS INT INC
摘要:Reagents suitable for synthesis of peptide analogs using automated peptide synthesis and procedures for synthesis of peptide analogs are provided.