CAS: 576-23-8; 2,3-Dimethylbromobenzene

上下游产品

CAS号87-59-2 2,3-二甲基苯胺 | CAS号526-75-0 2,3-二甲苯酚 | CAS号95-47-6 邻二甲苯 | CAS号7397-06-0 4-叔丁基邻二甲苯 | CAS号92-52-4 联苯 | CAS号61024-97-3 1-bromo-5-tert-... | CAS号22364-25-6 4-溴-2,3-二甲基苯胺 | CAS号593-53-3 氟甲烷 | CAS号95-46-5 2-溴甲苯 | CAS号105694-44-8 7-溴异苯并呋喃-1(3H)-酮 | CAS号95-65-8 3,4-二甲酚 | CAS号526-75-0 2,3-二甲苯酚 | CAS号923590-95-8 4-溴异吲哚啉盐酸盐 | CAS号923590-78-7 2-苄基-4-溴异吲哚啉 | CAS号1963-30-0 2,3-DIMETHYLCIN... | CAS号86347-15-1 盐酸美托咪啶 | CAS号21900-46-9 2,3-二甲基苯甲酰氯 | CAS号86347-14-0 美托咪定 | CAS号933-98-2 1,2-二甲基-3-乙基苯

2,3-二甲基苯胺置于硫酸,Sodium Nitrite,Potassium Bromide体系中,用 二氯甲烷,水 作为反应溶剂,化学反应 4.0H,以85.5%的收率获得产物2,3-二甲基溴苯
参考文献:一种合成α-Bpda的方法
标题:一种合成α-Bpda的方法
摘要:本发明公开了一种合成α‑bpda的方法,以2,3‑甲基溴苯和n‑甲基‑4‑氯代邻苯二甲酰亚胺为原料,将2,3‑甲基苯胺溶解于二氯甲烷中,采用硫酸成盐,进行重氮化反应,经水洗,浓缩,重结晶后得到2,3‑甲基溴苯,采用mg/硼酸三丁酯体系制备得到2,3‑甲基苯硼酸,再与n‑甲基‑4‑氯代邻苯二甲酰亚胺进行铃木偶联反应,得到5‑(2,3‑二甲基苯基)‑2‑甲基异吲哚‑1,3‑二酮,再通过氢氧化钠和高锰酸钾体系,碱解,氧化制备2,3,3',4'‑联苯四羧酸,最后在邻二甲苯体系中成酐,得到高纯度α‑bpda.该合成方法避免了传统方法中产物均为三种异构混合物,收率低,造成环境污染的问题.

专利信息

专利号:US-10053420-B2
优先权日:2015-01-30
标 题 :Processes for the preparation of compounds, such as 3-arylbutanals, useful in the synthesis of medetomidine
发明人：EKLUND LARS; EEK MARGUS; EKAMBARAM RAMESH; MAASALU ANTS
权利人:CAMBREX KARLSKOGA AB
摘要:There is provided a process for the preparation of a compound of formula (I) as defined herein, wherein said process comprises reacting a compound of formula (II) as defined s herein with one or more suitable Vilsmeier reagent.

专利号:US-9932423-B2
优先权日:2015-09-24
标题:Hydrogenation of annulated cyclopentadienyl metal complexes and metallocene catalysts comprising such
发明人：MCCULLOUGH LAUGHLIN G
权利人:EXXONMOBIL CHEMICAL PATENTS INC
摘要:Disclosed are methods for making partially hydrogenated annulated cyclopentadienyl complexes which can provide efficient synthesis of metallocene catalysts desired for olefin polymerization.

专利号:US-2022145179-A1
优先权日:2020-11-12
标题 :Synthesis of aryl 1-(methoxymethyl) vinyl ketones and their use as inhibitors of mild steel corrosion
发明人：MAZUMDER MOHAMMAD ABU JAFAR; ALI SHAIKH ASROF; ODEWUNMI NURUDEEN; ALHARBI BADER; ALJEABAN NORAH; CHEN TAO; BALHARTH SALEM
权利人:SAUDI ARABIAN OIL CO; UNIV KING FAHD PET & MINERALS
摘要:Methods for preparing alkenylphenone corrosion inhibiting compositions may include providing an arylacetone and reacting the arylacetone with formaldehyde in the presence of a strong base catalyst. Corrosion inhibiting compositions may include an alkenylphenone, which may be prepared by a method including providing an arylacetone and reacting the arylacetone with formaldehyde in the presence of a strong base catalyst. Methods of inhibiting corrosion of a steel surface of an oilfield equipment component may include contacting the steel surface with an aqueous solution comprising a corrosion inhibitor. The corrosion inhibitor may include a composition containing an alkenylphenone prepared by reacting an arylacetone with formaldehyde in the presence of a strong base catalyst.

专利号:US-6828466-B2
优先权日:2002-07-19
标题:Process for the synthesis of phenols from arenes
发明人：MALECZKA JR ROBERT E; SMITH III MILTON R; HOLMES DANIEL; SHI FENG
权利人:UNIV MICHIGAN STATE
摘要:A process to synthesize substituted phenols such as those of the general formula RR'R''Ar(OH) wherein R, R', and R'' are each independently hydrogen or any group which does not interfere in the process for synthesizing the substituted phenol including, but not limited to, halo, alkyl, alkoxy, carboxylic ester, amine, amide; and Ar is any variety of aryl or hetroaryl by means of oxidation of substituted arylboronic esters is described. In particular, a metal-catalyzed C-H activation/borylation reaction is described, which when followed by direct oxidation in a single or separate reaction vessel affords phenols without the need for any intermediate manipulations. More particularly, a process wherein Ir-catalyzed borylation of arenes using pinacolborane (HBPin) followed by oxidation of the intermediate arylboronic ester by OXONE is described.

专利号:US-6620824-B2
优先权日:2001-04-11
标 题:Process for the synthesis of gonadotropin releasing hormone antagonists
发明人：CHUNG JOHN Y L; FARR ROGER N; HUMPHREY GUY R
权利人:MERCK & CO INC
摘要:The present invention relates to a process for preparing a compound of gonadotropin releasing hormone antagonists having a Formula I, n in an efficient way, which involves preparation of key intermediates: 2-arylindole core; a chiral aziridine, in particular chiral nosyl aziridine; and an amine salt. The key process involves the coupling reaction of 2-arylindole and nosyl aziridine under boron trifluoride catalysis, which provides the final compound with unprecedented regioselectivity and enantioselectivity.

专利号:US-6657068-B2
优先权日:2002-03-22
标题:Liquid phase oxidation of halogenated ortho-xylenes
发明人：COLBORN ROBERT EDGAR; HALL DAVID BRUCE; KOCH PETER; OECKEL GERALD
权利人:GEN ELECTRIC
摘要:A method for the manufacture of halophthalic acid by liquid phase oxidation of halo-ortho-xylene is disclosed. The halophthalic acid may be dehydrated to form halophthalic anhydride which is useful in the synthesis of polyetherimide.