CAS: 768-33-2; Chlorodimethyl(Phenyl)Silane

上下游产品

CAS号766-77-8 二甲基苯烷 | CAS号108-86-1 溴苯 | CAS号75-78-5 二甲基二氯硅烷 | CAS号107-05-1 氯丙烯 | CAS号1825-58-7 苯基二甲基乙氧基硅 | CAS号1145-98-8 二苯基四甲基二硅烷 | CAS号37865-47-7 dimethyl-phenyl... | CAS号4342-61-4 二氯四甲基二硅烷 | CAS号98-88-4 苯甲酰氯 | CAS号852064-26-7 (E)-1-dimethyl(... | CAS号1145-98-8 二苯基四甲基二硅烷 | CAS号10536-53-5 bis[[dimethyl(p... | CAS号35583-33-6 rac-4-phenyl°Ct... | CAS号100103-32-0 4-[dimethyl(phe... | CAS号454-57-9 二甲基苯基氟硅烷 | CAS号3449-26-1 1,3-联苯基四甲基二硅氮烷 | CAS号98-85-1 苏合香醇 | CAS号146758-90-9 (1-but-1-ynylcy... | CAS号14311-78-5 (4-methoxypheny... | CAS号17156-64-8 (二甲基苯基甲硅烷基)乙酰亚基

苯基二甲基乙氧基硅置于cobalt(Ii,Iii) Oxide,氯甲基乙醚体系中,用 氯仿 作为反应溶剂,化学反应 4.0H,以82%的收率获得产物苯基二甲基氯硅烷
参考文献:ハロシランの製造方法
标题:ハロシランの製造方法
摘要:这是一段关于制造卤代硅烷的方法的专利描述.

专利信息

专利号:US-8293930-B1
优先权日:2004-06-25
标题 :One pot synthesis of taxane derivatives and their conversion to paclitaxel and docetaxel
发明人：NAIDU RAGINA
权利人:NAIDU RAGINA; CHATHAM BIOTEC LTD
摘要:A process is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis of protected taxane intermediate in a one pot reaction of protecting the C-7 and C-10 positions and attaching a side chain at the C-13 position and subsequently deprotecting the group to form paclitaxel or docetaxel, and taxane intermediates.

专利号:US-7893283-B2
优先权日:2004-06-04
标题:Semi-synthesis of taxane intermediates and their conversion to paclitaxel and docetaxel
发明人：NAIDU RAGINA
权利人:CHATHAM BIOTEC LTD
摘要:A process is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis of protected taxane intermediates.

专利号:US-9688644-B2
优先权日:2009-04-30
标 题 :Synthesis of Tetracyclines and intermediates thereto
发明人：MYERS ANDREW G; KUMMER DAVID A; LI DERUN; HECKER EVAN; DION AMELIE; WRIGHT PETER M
权利人:HARVARD COLLEGE
摘要:The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The recent development of a modular synthesis of tetracycline analogs through a chiral enone intermediate has allowed for the efficient synthesis of novel tetracycline analogs never prepared before. The present invention provides more efficient routes for preparing the enone intermediate and allows for substituents at positions 4a, 5, 5a, and 12a of the tetracycline ring system.

专利号:WO-2008032104-A1
优先权日:2006-09-15
标题:One pot synthesis of taxane derivatives and their conversion to paclitaxel and docetaxel
发明人：WALKER ROSS THOMSON; NAIDU RAGINA
权利人:CHATHAM BIOTEC LTD; WALKER ROSS THOMSON; NAIDU RAGINA
摘要:A process is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis of protected taxane intermediate in a one pot reaction, of protecting the C-10 and attaching a side chain at C-13 position and subsequently deprotecting the group to form paclitaxel or docetaxel, and intermediates used therein.

专利号:US-7202370-B2
优先权日:2003-10-27
标 题 :Semi-synthesis of taxane intermediates from 9-dihydro-13-acetylbaccatin III
发明人：NAIDU RAGINA
权利人:CONOR MEDSYSTEMS INC
摘要:A method is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel from 9-dihydro-13-acetylbaccatin III. The preparation of a suitably protected baccatin III backbone from 9-dihydro-13-acetylbaccatin III, and the insertion of the phenylisoserine side chain onto the protected baccatin III from 9-dihydro-13-acetylbaccatin III to form the taxane derivatives, paclitaxel and docetaxel is disclosed.

专利号:US-7838694-B2
优先权日:2004-04-23
标题 :Semi-synthesis and isolation of taxane intermediates from a mixture of taxanes
发明人：NAIDU RAGINA; FOO SAMUEL SIANG KIANG
权利人:CHATHAM BIOTEC LTD
摘要:A process is provided for the semi-synthesis and isolation of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis and isolation of 10-deacetylbaccatin III, the semi-synthesis of a mixture of 10-deacetylbaccatin III and baccatin III, and protected derivatives thereof, from a mixture of taxanes.