CAS: 76822-21-4; (R)-3-(3,4-Dihydroxyphenyl)-2-Hydroxypropanoic Acid

上下游产品

(Z)-3-(3,4-dihydroxyphenyl)-2-hydroxyacrylic acid clinopodic acid C (R)-(+)-rosmarinic acid lycopic acid A(+/-)-(R)-methyl 3-(3,4-dimethoxyphenyl)-2-hydroxypropanoate (R)-(+)-rosmarinic acid (2R)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanoic acid (S)-PGME amide (2R)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanoic acid (R)-PGME amide

丹酚酸 B置于sodium Hydroxide体系中,用 乙醇 作为反应溶剂,化学反应 1.5H,反应生成 丹参素
参考文献:一种丹酚酸b转化为丹参素的方法
标题:一种丹酚酸b转化为丹参素的方法
摘要:本发明公开的一种丹酚酸b转化为丹参素的方法,其首先采用ph调节剂将丹参提取液的ph调节到7.0~12.0,然后加热回流进行转化得到丹参提取转化液,转化温度为80oc~120°C,转化时间为0.5H~4H,最后采用ph调节剂将丹参提取转化液的ph调节到2.0~6.0.本发明丹酚酸b转化为丹参素较为彻底,转化后丹酚酸b含量低于1.0Mg/ml;转化过程中不需要使用乙醇,丙酮,乙酸乙酯等有机溶媒;转化后存放其含量稳定;操作简单,不需要投入设备.

专利信息

专利号:US-12173333-B2
优先权日:2017-08-07
标 题:Variants of family a DNA polymerase and uses thereof
发明人：YBERT THOMAS; CHAMPION ELISE; VIVAR OMAR; SAID AHMED
权利人:DNA SCRIPT
摘要:The present invention relates to variant of Family A polymerases able to synthesize a nucleic acid fragment without template and to incorporate a reversible modified terminator nucleotide during the nucleic acid fragment synthesis. The present invention further relates to uses thereof for enzymatic synthesis of nucleic acid molecules.

专利号:US-2024084338-A1
优先权日:2022-11-22
标 题 :Recombinant Escherichia coli for producing rosmarinic acid and its application thereof
发明人：ZHOU JINGWEN; CHEN JIAN; WANG LIAN; ZENG WEIZHU; YU SHIQIN
权利人:UNIV JIANGNAN
摘要:The present disclosure discloses a recombinant Escherichia coli for producing rosmarinic acid and application thereof, belonging to the technical fields of genetic engineering and bioengineering. In the present disclosure, FjTA derived from Flavobacterium johnsoniae, endogenous hpaBC derived from E. coli, CbRAS derived from Coleus blumei, HPPR derived from Coleus scutellarioides, and Pc4CL1 derived from Petroselinum crispum are heterologously expressed in E. coli, realizing synthesis of rosmarinic acid. TcTAL derived from Trichosporon cutaneum and tyrC for removing feedback inhibition are introduced, further increasing synthesis throughput of caffeic acid, and PmLAAD derived from Proteus myxofaciens is heterologously expressed, realizing redistribution of L-DOPA. An endogenous gene menl is knocked out, improving the content and stability of a rosmarinic acid precursor. The recombinant strain constructed in the present disclosure can produce rosmarinic acid by fermentation at a yield of up to 511.2 mg/L, providing a new method for industrial production of rosmarinic acid.

专利号:CN-103833546-A
优先权日:2014-02-25
标 题 :Asymmetric Synthesis of Optically Pure Danshensu and Its Derivatives

专利号:CN-103833546-B
优先权日:2014-02-25
标 题:Asymmetric Synthesis of Optically Pure Danshensu and Its Derivatives

专利号:CN-102863328-B
优先权日:2012-05-15
标 题:Synthesis method of tanshinol

专利号:CN-104341481-B
优先权日:2013-08-09
标 题 :The synthesis and application of a kind of sulfonamide compounds