CAS: 100-38-9; 2-(Diethylamino)Ethanethiol

该化合物是一种具有分子式C6H15NS的硫醇功能化矿化合物,其结构具有二乙基氨基化合物和终端硫醇混合物的特点,使其成为有机合成和协调化学的多种试剂.该化合物由于通过硫磺原子紧密结合,对金属复合体特别有用,有利于催化和材料科学的应用.此外,其双重功能允许对聚合物化学和表面功能化进行修改.该硫醇混合物还有利于生物化学应用中的同质化.该化合物由于对氧化的敏感性,通常在不热的条件下处理.

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CAS号100-35-6 N,N-二乙基氯乙胺 | CAS号420-12-2 环硫乙烷 | CAS号816-43-3 二乙氨基锂 | CAS号109-89-7 二乙胺 | CAS号100-37-8 二乙氨基乙醇 | CAS号55847-36-4 S-(2-chloroethy... | CAS号5842-22-8 thi°Carbonic ac... | CAS号5978-05-2 Butylcarbamidsa... | CAS号64-17-5 乙醇 | CAS号14441-55-5 Benzenecarbothi... | CAS号4358-87-6 DL-扁桃酸甲酯 | CAS号23713-11-3 Phosphorodithio... | CAS号589-32-2 四乙基胱胺-13C4 | CAS号15904-54-8 2-(diethylamino... | CAS号115986-18-0 N,N-diethyl-2-(... | CAS号7708-55-6 2-benzylsulfany... | CAS号78-53-5 胺吸磷 | CAS号82-99-5 S-[2-(diethylam... | CAS号88873-85-2 3-[2-(diethylam...

合成工艺路线路线简述

  • 合成目标产物 2-Diethylaminoethanethiol 主要起始原料 Diethylaminoethanol
  • (文献来源)合成步骤主要原料 Diethylaminoethanol
N,N-二乙基氯乙胺置于乙醇,Alkali Hydrogensulfide体系中,化学反应生成2-二乙氨基乙硫醇
参考文献:M Easurement Of P Ediatric I Llness S Everity U Sing S Imple P Retransport V Ariables
标题:M Easurement Of P Ediatric I Llness S Everity U Sing S Imple P Retransport V Ariables
摘要:Objective: To Test The Hypothesis That Pretransport Variables Can Predict In-Hospital Mortality That Will Correlate With Major Interventions And Unplanned Events During Interfacility Transport. Methods: A Cohort Of Children (N = 2,253) Transported By A Specialized Pediatric Team To A Children'S Hospital Were Studied. At The Time Of Referral,Data Collected Included Age (Months),Heart Rate,Systolic Blood Pressure,Respiratory Rate,Retractions,Stridor Or Wheezing,Seizures,Skin Perfusion,Oxygen Requirement,And Mental Status. Using Univariate And Stepwise Logistic Regression,Variables Predictive Of In-Hospital Mortality Were Selected From A Training Set (N = 1,111) And Assigned Integers Based On Their Computed Coefficients. Probability Of In-Hospital Mortality Was Calculated Using The Total Integer Score And Age. The Risk Of Mortality Derived From The Training Set Was Validated In The Remaining Patients (N = 1,142) By Comparing The Observed And Predicted Mortalities. Major Interventions Performed And Unplanned Events Were Determined For Each Of Five Predetermined Mortality Risk Groups. Results: Variables (Integers) Predicting In-Hospital Mortality Included Systolic Blood Pressure (11),Respiratory Rate (6),Oxygen Requirement (11),And Altered Mental Status (11). Observed Mortality Was Similar To Predicted Mortality In All Risk Categories For The Validation Sample. As Risk Of Mortality Increased,So Did The Performance Of Major Interventions And The occurrence Of Unplanned Events. Conclusion: Four Pretransport Variables Predicted In-Hospital Mortality. Risk Of Mortality Correlated With The Incidence Of Major Patient Interventions,And The occurrence Of Unplanned Events Increased As Well. This Model Might Be Useful In Comparing Different Transport Systems Using Severity-Adjusted Assessment Of Children Requiring Interfacility Transport.
Doi:10.1080/10903120190939986

专利信息


专利号:US-2008242877-A1
优先权日:2007-02-26
标题 :Intermediates and processes for the synthesis of Ramelteon
发明人:KANSAL VINOD KUMAR; MISTRY DHIRENKUMAR N; VASOYA SANJAY L
权利人:KANSAL VINOD KUMAR; MISTRY DHIRENKUMAR N; VASOYA SANJAY L
摘要:Provided are intermediates and processes for preparation of Ramelteon.

专利号:US-2018208555-A1
优先权日:2013-11-18
标题 :Method of synthesis of an ionizable cationic lipid

专利号:US-10781169-B2
优先权日:2013-11-18
标 题:Method of synthesis of an ionizable cationic lipid

专利号:US-2021002217-A1
优先权日:2013-11-18
标题:Method of synthesis of an ionizable cationic lipid

专利号:WO-2023113033-A1
优先权日:2021-12-16
标题 :Gas diffusion electrode
发明人:KONDO SHOICHI; MAEDA SHINICHI; SHIGA NORIHITO
权利人:NISSAN CHEMICAL CORP
摘要:[Problem] The present invention addresses the problem of increasing the rate of reaction by controlling ammonium ions, which are generated by ammonia as the objective of the electrolytic synthesis of ammonia and protons that are supplied to the cathode, by means of the cathode and the cathode catalyst layer. [Solution] The present invention provides a gas diffusion electrode which is integrated with a catalyst layer that uses a material selected from the group consisting of cathode catalyst layer materials. Examples of the cathode catalyst layer materials include a fired body and an ionic liquid.

专利号:US-2020140380-A9
优先权日:2013-11-18
标 题 :Method of synthesis of an ionizable cationic lipid
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✅ COA系统入驻 | 共享模式

主要参考文献


1: CURZON G, SCHNIEDEN H. THE EFFECT OF COPPER SULPHATE ON THE LD-50 OF CYSTEAMINE AND NN-DIETHYLCYSTEAMINE AND ON TREMOR INDUCED BY THESE COMPOUNDS. Biochem Pharmacol. 1965 Mar;14:289-94. doi: 10.1016/0006-2952(65)90193-0.

合成参考文献


摘要:Biochemical Pharmacology., 14(289), 1965 []
参考文献:10.1007/s00216-006-0531-1
摘要:Shulga OV, Palmer C. Detection of V-type nerve agent degradation products at electrodes modified by PPy/PQQ using CaCl2 as supporting electrolyte. Analytical and Bioanalytical Chemistry. 2006 Jun 13;385(6):1116–23. doi: 10.1007/s00216-006-0531-1.
参考文献:10.1021/ac049658b
摘要:Wang J, Zima J, Lawrence NS, Chatrathi MP, Mulchandani A, Collins GE. Microchip capillary electrophoresis with electrochemical detection of thiol-containing degradation products of V-type nerve agents. Anal Chem. 2004 Aug 15;76(16):4721–6. doi: 10.1021/ac049658b.
参考文献:10.1021/jo0611059
摘要:Magano J, Chen MH, Clark JD, Nussbaumer T. 2-(Diethylamino)ethanethiol, a new reagent for the odorless deprotection of aromatic methyl ethers. J Org Chem. 2006 Sep 01;71(18):7103–5. doi: 10.1021/jo0611059.
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