专利号:US-4375544-A 优先权日:1978-01-28 标 题:Fused pyridines 发明人:METH-COHN OTTO; NARINE BRAHMA 权利人:CRODA SYNTHETIC CHEM LTD 摘要:PCT No. PCT/GB79/00017 Sec. 371 Date Jun. 8, 1979 Sec. 102(e) Date Jun. 8, 1979 PCT Filed Jan. 24, 1979 PCT Pub. No. WO79/00540 PCT Pub. Date Aug. 9, 1979.Aromatic- alpha -halo-{b} fused pyridines are made by reacting an aromatic acetamide, acid halide and amide in particular proportions, with the acid halide always in excess. The process permits the production of compounds having a wide range of substituents, that are new compounds, and that are of value as intermediates in the synthesis of, for instance, pharmaceutical compounds.