CAS: 13679-75-9; 2-Propionylthiophene

相似化合物

33898-90-7 88-15-3 229970-94-9

上下游产品

2-乙酰基噻吩 2-Acetylthiophene 88-15-3
3-二甲基氨基-1-(2-噻吩基)-1-丙酮 3-(Dimethylamino)-1-(Thiophen-2-yl)Propan-1-One 13196-35-5
Thienyl Vinyl Ketone 13191-29-2
2-丙基噻吩 2-Propylthiophene 1551-27-5

2-Allylthiophene置于叔丁基过氧化氢,Palladium Diacetate,对甲苯磺酸体系中,用 水,乙腈 用作溶剂,化学反应 6.0H,以86%的收率获得1-(2-噻吩基)-1-丙酮
参考文献:Direct Conversion Of Allyl Arenes To Aryl Ethylketones Via A Tbhp-Mediated Palladium-Catalyzed Tandem Isomerization-wacker Oxidation Of Terminal Alkenes
标题:Direct Conversion Of Allyl Arenes To Aryl Ethylketones Via A Tbhp-Mediated Palladium-Catalyzed Tandem Isomerization-wacker Oxidation Of Terminal Alkenes
摘要:通过tbhp介导的钯催化串联异构化-Wacker氧化反应,成功开发了对末端烯烃的反应.
Doi:10.1039/c5Ob00586H

专利信息

专利号:US-4886924-A
优先权日:1988-10-17
标题:Stereospecific synthesis of [E]-alkenes from enamines via hydroboration
发明人：GORALSKI CHRISTIAN T; SINGARAM BAKTHAN; BROWN HERBERT C
权利人:DOW CHEMICAL CO
摘要:A process for the stereospecific synthesis of [E] alkenes from enamines comprising the steps of hydroborating the enamine; esterifying the organoborane so formed and oxidizing the boronic ester in the presence of hydrogen peroxide and in the absence of added base under conditions sufficient to form the [E] alkene in high yield.

专利号:US-6413957-B1
优先权日:1998-04-21
标题:Methods of inhibiting cell proliferation using indeno [1,2-c]pyrazol-4-ones
发明人：NUGIEL DAVID A; CARINI DAVID J; DI MEO SUSAN V; YUE EDDY W
权利人:BRISTOL MYERS SUIBB PHARMA COM
摘要:The present invention relates to the synthesis of a new class of indeno[1,2-c]pyrazol-4-ones of formula (I): n that are potent inhibitors of the class of enzymes known as cyclin dependent kinases, which relate to the catalytic subunits cdk1-7 and their regulatory subunits know as cyclins A-G. This invention also provides a novel method of treating cancer or other proliferative diseases by administering a therapeutically effective amount of one of these compounds or a pharmaceutically acceptable salt form thereof. Alternatively, one can treat cancer or other proliferative diseases by administering a therapeutically effective combination of one of the compounds of the present invention and one or more other known anti-cancer or anti-proliferative agents.

专利号:US-7250435-B2
优先权日:1999-10-20
标 题:Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents
发明人：NUGIEL DAVID A; CARINI DAVID J; DI MEO SUSAN V; VIDWANS ANUP P; YUE EDDY
权利人:BRISTOL MYERS SQUIBB PHARMA CO
摘要:The present invention relates to the synthesis of a new class of indeno[1,2-c]pyrazol-4-ones of formula (I): n nthat are potent inhibitors of the class of enzymes known as cyclin dependent kinases, which relate to the catalytic subunits cdk1-7 and their regulatory subunits know as cyclins A-G.n n This invention also provides a novel method of treating cancer or other proliferative diseases by administering a therapeutically effective amount of one of these compounds or a pharmaceutically acceptable salt form thereof. Alternatively, one can treat cancer or other proliferative diseases by administering a therapeutically effective combination of one of the compounds of the present invention and one or more other known anti-cancer or anti-proliferative agents.

专利号:US-6407103-B2
优先权日:1998-04-21
标 题:Indeno [1,2-c] pyrazol-4-ones and their uses
发明人：NUGIEL DAVID A; CARINI DAVID J; DI MEO SUSAN V; YUE EDDY W
权利人:BRISTOL MYERS SQUIBB PHARMA CO
摘要:The present invention relates to the synthesis of a new class of indeno[1,2-c]pyrazol-4-ones of formula (I):that are potent inhibitors of the class of enzymes known as cyclin dependent kinases, which relate to the catalytic subunits cdk1-9 and their regulatory subunits know as cyclins A-H.This invention also provides a novel method of treating cancer or other proliferative diseases by administering a therapeutically effective amount of one of these compounds or a pharmaceutically acceptable salt form thereof. Alternatively, one can treat cancer or other proliferative diseases by administering a therapeutically effective combination of one of the compounds of the present invention and one or more other known anti-cancer or anti-proliferative agents.

专利号:CN-108906124-A
优先权日:2017-03-17
标 题 :Application of Tricene Rare Earth Metal Complexes as Catalysts in the Synthesis of Ketones and Pinacol-Borane

专利号:US-6593356-B2
优先权日:1999-10-20
标 题 :Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents
发明人：NUGIEL DAVID; CARINI DAVID; DIMEO SUSAN; VIDWANS ANUP; YUE EDDY
权利人:BRISTOL MYERS SQUIBB PHARMA CO
摘要:The present invention relates to the synthesis of a new class of indeno[1,2-c]pyrazol-4-ones of formula (I):that are potent inhibitors of the class of enzymes known as cyclin dependent kinases, which relate to the catalytic subunits cdk1-7 and their regulatory subunits know as cyclins A-G.This invention also provides a novel method of treating cancer or other proliferative diseases by administering a therapeutically effective amount of one of these compounds or a pharmaceutically acceptable salt form thereof. Alternatively, one can treat cancer or other proliferative diseases by administering a therapeutically effective combination of one of the compounds of the present invention and one or more other known anti-cancer or anti-proliferative agents.