CAS: 485799-04-0; 4-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Pyridin-2-yl)Morpholine

相似化合物

904326-93-8 1356068-62-6 1684430-48-5

上下游产品

CAS号73183-34-3 双戊酰二硼 | CAS号200064-11-5 5-溴-2-吗啉吡啶

5-溴-2-氯吡啶置于1,1'-双(二苯膦基)二茂铁二氯化钯(II)二氯甲烷复合物,Potassium Acetate,Caesium Carbonate体系中,用 1,4-二氧六环,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 14.0H,反应生成 6-(吗啉-4-基)吡啶-3-硼酸频哪醇酯
参考文献:Wo2020081636A5
标题:Wo2020081636A5

专利信息

专利号:US-7638633-B2
优先权日:2005-02-21
标题 :Process for synthesis of proton pump inhibitors
发明人：PATHI SRINIVAS LAXMINARAYAN; KANKAN RAJENDRA NARAYANRAO; RAO DHARMARAJ RAMACHANDRA
权利人:CIPLA LTD
摘要:A process for preparation of rabeprazole sodium comprising oxidation of wet or dry rabeprazole sulphide with sodium hypohalite in water or a mixture of water and water miscible solvent using alkali metal hydroxide and catalyst is disclosed herein. The present invention also discloses process for preparation of rabeprazole sulphide.

专利号:EP-2354120-A1
优先权日:2003-08-20
标题 :Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
发明人：GALLOP MARK A; YAO FENMEI; LUDWIKOW MARIA J; PHAN THU; PENG GE
权利人:XENOPORT INC
摘要:The present invention relates to acyloxyalkyl carbamate prodrugs of (±)-4-amino-3-(4-fluorophenyl)butanoic acid and analogs thereof, pharmaceutical compositions thereof, methods of making prodrugs of (±)-4-amino-3-(4-fluorophenyl)butanoic acid and analogs thereof, methods of using prodrugs of (±)-4-amino-3-(4-tluorophenyl)butanoic acid and analogs thereof, and pharmaceutical compositions thereof for treating or preventing common diseases and/or disorders such as spasticity and/or acid reflux disease. The present invention also relates to acyloxyalkyl carbamate prodrugs of (±)-4-amino-3-(4-fluorophenyl)butanoic acid and analogs thereof which are suitable for oral administration and to sustained release oral dosage forms thereof.

专利号:AT-E473222-T1
优先权日:2005-02-21
标 题:NEW METHOD FOR SYNTHESIS OF PROTON PUMP INHIBITORS

专利号:US-7935686-B2
优先权日:2004-11-03
标 题 :Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use
发明人：GALLOP MARK A
权利人:XENOPORT INC
摘要:Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphonous acid, 3-aminopropylphosphinic acid, and analogs thereof, pharmaceutical compositions comprising acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphonous acid, 3-aminopropylphosphinic acid, and analogs thereof, methods of making prodrugs of 3-aminopropylphosphonous acid, 3-aminopropylphosphinic acid, and analogs thereof, methods of using prodrugs of 3-aminopropylphosphonous acid, 3-aminopropylphosphinic acid, and analogs thereof and pharmaceutical compositions thereof for treating or preventing diseases or disorders such as spasticity or gastroesophageal reflux disease are disclosed. Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphonous acid, 3-aminopropylphosphinic acid, and analogs thereof and sustained release oral dosage forms thereof, which are suitable for oral administration, are also disclosed.

专利号:US-2008161579-A1
优先权日:2005-02-21
标题 :Process for Synthesis of Proton Pump Inhibitors

专利号:US-7566738-B2
优先权日:2004-11-03
标题 :Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
发明人：GALLOP MARK A
权利人:XENOPORT INC
摘要:Acyloxyalkyl carbamate prodrugs of 3-aminopropylsulfinic acid and analogs thereof, pharmaceutical compositions of 3-aminopropylsulfinic acid and analogs thereof, methods of making prodrugs of 3-aminopropylsulfinic acid and analogs thereof, methods of using prodrugs of 3-aminopropylsulfinic acid and analogs thereof, and pharmaceutical compositions thereof for treating or preventing diseases or disorders such as spasticity or gastroesophageal reflux disease are disclosed. Acyloxyalkyl carbamate prodrugs of 3-aminopropylsulfinic acid and analogs thereof and sustained release oral dosage forms thereof, which are suitable for oral administration, are also disclosed.